Zhishang Chemical

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Zhishang Chemical

P-Methoxybenzoic Acid CAS 100-09-4

Molecular Formula: C8H8O3

Formula Weight: 152.15

ZSpharmac: P-Methoxybenzoic Acid Raw Material Supplier

Product Name: P-Methoxybenzoic Acid
CAS No: 100-09-4
Purity: 99%

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Basic Info

Product Name:P-Methoxybenzoic Acid
Other Names:4-Methoxybenzoic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Slightly Gray-Beige Powder
EINECS No.:202-818-5
Storage:Store Below +30°C
Provide:P-Methoxybenzoic Acid MSDS;
P-Methoxybenzoic Acid COA

What is P-Methoxybenzoic Acid?

Methoxybenzoic acid, additionally called p-anisic acid, 4-anisic acid, and anisic acid, is colorless needle-shaped crystals at space temperature level. It is soluble in ethanol, ether, and Chemicalbook chloroform, and is somewhat soluble in hot water. It is tough to Soluble in cold water. The intermediate p-methoxybenzoyl chloride of amiodarone is prepared by chlorination with thionyl chloride. It is made use of as a pharmaceutical intermediate of Solaracetam, and can also be made use of as a flavor and preservative.

P-Methoxybenzoic Acid Property

Melting point 

182-185 °C(lit.)

Boiling point 

275 °C



vapor pressure 

0.001Pa at 25℃

refractive index 



185 °C

storage temp. 

Store below +30°C.


H2O: soluble2500 parts


4.50(at 25℃)




White to slightly gray-beige


3-4 (0.3g/l, H2O, 20℃)


at 10.00 % in dipropylene glycol. faint putrid sweet cadaverous

Odor Type


Water Solubility 

Soluble in water at 20°C 0.3g/L. Soluble in alcohol, ethyl acetate and ether.


P-Methoxybenzoic Acid Uses

  1. The major use P-Methoxybenzoic Acid in the scent market is to different anishole as a starting factor for the preparation of anisaldehyde, anisyl alcohol, anisic acid (p-methoxybenzoic acid) and its esters Basic material, it is likewise utilized in food tastes, tooth paste, tooth powder, alcohol, candy, beverages and cigarette, and a percent is utilized in day-to-day tastes.
  2. P-Methoxybenzoic Acid is a generally utilized flavoring spice. It has medical impacts such as tasty, reducing qi, warming up the kidneys and spreading out trendy. Fennel oil is made use of medicinally as the major raw material for the synthesis of the unfavorable hormonal agent hexabestrol.

Production Method of P-Methoxybenzoic Acid

The commercial manufacturing technique of p-methoxybenzoic acid is to utilize dimethyl sulfate to methylate p-hydroxybenzoic acid under alkaline conditions. Since p-hydroxybenzoic acid has a carboxyl group, more methylation is taken in. Alkali requires to be acidified with acid after the reaction, and p-hydroxybenzoic acid is also much more costly, therefore increasing the price. Meng Xiangjun, Zhang Baofa, and Ge Xin once reported using p-cresol as basic material to prepare p-methoxybenzoic acid through methylation and oxygen oxidation. Nonetheless, dimethyl sulfate is also made use of throughout methylation in this procedure, which additionally takes in a great deal of alkali and needs two steps to finish; in the process of oxygen oxidation, steel salts such as CoBr2 and MnBr2 likewise need to be made use of as drivers. While triggering heavy metal air pollution, it additionally boosts the expense of the procedure.

CN103848736A gives a synthesis approach of p-methoxybenzoic acid, which is identified in that it includes the complying with actions:
a. Add (4-methoxybenzyl) trimethylsilane right into the activator, include anhydrous solvent, and afterwards include the catalyst;

b. Connect the oxygen-filled bladder to the quartz activator and remove the air in the system so that the reaction continues under the oxidation of pure oxygen; or link the round condenser tube to the quartz reactor to permit the reaction to continue under the oxidation of air conduct;

c. Area the connected reactor under the irradiation of a xenon light (300W) to react; after the reaction item is identified by TLC and high performance fluid chromatography (4-methoxybenzyl)trimethylsilane to have entirely responded, vacuum rotating evaporation, Column chromatography separation and purification.

Contact Us

About Products:
If you need the cosmetic raw material P-Methoxybenzoic Acid, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced P-Methoxybenzoic Acid manufacturer and supplier, our company, ZSpharmac will provide P-Methoxybenzoic Acid raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get P-Methoxybenzoic Acid Quotation