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P-Methoxyacetophenone CAS 100-06-1

Molecular Formula: C9H10O2

Formula Weight: 150.17

ZSpharmac: P-Methoxyacetophenone Raw Material Supplier

Product Name: P-Methoxyacetophenone
CAS No: 100-06-1
Purity: 99%

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Basic Info

Product Name:P-Methoxyacetophenone
Other Names:4′-Methoxyacetophenone
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystals or Crystalline Powder
EINECS No.:202-815-9
Storage:Room Temperature
Provide:P-Methoxyacetophenone MSDS;
P-Methoxyacetophenone  COA

What is P-Methoxyacetophenone?

p-Methoxyacetophenone is an organic compound, its chemical name is 4-methoxyacetophenone or 4′-methoxyacetophenone, and its English name is 4-Methoxyacetophenone. Its chemical formula is C9H10O2, its molecular weight is 150.17 g/mol, and its CAS registration number is 100-06-1.

From a chemical structure point of view, it is a derivative in which one hydrogen atom on the benzene ring is replaced by an ethyl ketone group (-COCH3), and another position of the benzene ring is substituted by a methoxy group (-OCH3). This compound appears in a crystalline form and has a strong hay aroma, coumarin-like notes, and floral and hawthorn notes.

P-Methoxyacetophenone Property

Melting point 

36-38 °C (lit.)

Boiling point 

152-154 °C/26 mmHg (lit.)



vapor pressure 

0.42Pa at 20℃

refractive index 

1.5470 (estimate)


>230 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature


H2O: soluble2.474g/L at 20°C


Crystals or Crystalline Powder




at 100.00 %. sweet hawthorn anisic powdery balsamic acacia

Odor Type


Water Solubility 



Uses of P-methoxyacetophenone

Flavors and fragrances industry:
In daily chemical fragrance formulas, p-methoxyacetophenone, with its unique hawthorn flower and anisaldehyde-like fragrance, is widely used in the fragrance formulations of soaps, synthetic detergents and other personal care products to enhance the aroma of the products. quality.
As a basic raw material for cosmetic flavors, especially for the preparation of high-end cosmetics and soap flavors, it can give products a soft and long-lasting aromatic character.

Food additives:
As a food-grade flavor ingredient, p-methoxyacetophenone is often used to prepare flavors for fruit foods and certain sweets, such as candies, pastries, beverages, etc., which can simulate the taste of natural fruits or specific vanilla.

Pharmaceutical intermediates:
Although not explicitly mentioned in the direct use description, it may serve as a synthetic intermediate in the pharmaceutical industry and participate in the synthesis of certain drugs or active ingredients.

Material science:
Although not its mainstream use, p-methoxyacetophenone has been mentioned in some literature as a liquid crystal raw material, indicating that it may play a role in the fields of display technology and optical materials.

Dyes and Pigments:
For some special types of dyes or pigments, p-methoxyacetophenone may exist as a precursor or auxiliary raw material, but this needs to be confirmed by specific application scenarios.

Characteristics of P-Methoxyacetophenone

Distinctive aroma characteristics:
Paramethoxyacetophenone has a strong, persistent and distinctive aroma, often described as hay, coumarin, floral, hawthorn and fruit, as well as notes similar to vanilla, nuts, butter and even caramel. , making it an important fragrance raw material, widely used in various fragrance formulas, giving products rich aroma levels.

Excellent stability:
In alkaline media, p-methoxyacetophenone shows good stability, which makes it suitable for use in the manufacture of daily chemical fragrances in alkaline environments such as soaps and synthetic detergents, ensuring that the fragrance remains in the final product. Durable release in .

Not only limited to daily chemical products, p-methoxyacetophenone is also an important component of food flavors and can be used in the production of food flavors with various flavors such as butter, nuts, chocolate, tobacco candies, fresh fruits, nuts, and vanilla beans. , increase the taste and flavor of food.

Synthetic convenience:
The compound can be synthesized through a relatively simple chemical reaction pathway, such as from anisole and acetyl chloride through Friedel-Crafts reaction. The sources of raw materials are relatively wide and the reaction conditions are controllable, making industrial production feasible.

Good solubility:
It can be well dissolved in organic solvents such as ethanol, making it easy to mix evenly with other flavors and raw materials, thus facilitating the preparation process of flavors.

Safety and regulatory compliance:
p-Methoxyacetophenone is approved by the state as a food flavoring and has no special restrictions in the International Flavors and Fragrances Association (IFRA) standards.

Organic synthesis value:
In addition to being a fragrance, p-methoxyacetophenone can also be used as an important intermediate in organic synthesis, such as in the production of p-methoxyphenylacetic acid.


Chan WS, Ma C, Kwok WM, Phillips DL. Time-resolved resonance Raman and density functional theory study of hydrogen-bonding effects on the triplet state of p-methoxyacetophenone. J Phys Chem A. 2005 Apr 21;109(15):3454-69. doi: 10.1021/jp044546+. PMID: 16833683.

About Products:
If you need P-Methoxyacetophenone, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced P-Methoxyacetophenone manufacturer and supplier, our company, ZSpharmac will provide P-Methoxyacetophenone raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get P-Methoxyacetophenone Quotation