p-Methoxyacetophenone is a food flavoring allowed by nationwide laws and is sensitive to light. Soluble in ethanol, somewhat soluble in water. It has a strong hawthorn fragrance and is an important resources for mimosa, hawthorn and various other scents. It is suitable for fragrances such as hawthorn blossom, acacia, mimosa, acacia, great smelling myrtle, orchid, brand-new trimming turf, clover and various other scents. It has high security in soap and is commonly made use of in premium cosmetics and cosmetics with herbal fragrance and woody scent. In soap scent; likewise used in the production of sun block, p-methoxyphenylacetic acid (puerarin intermediate), p-methoxystyrene and fluid crystal monomer.
Application 1. CN201210268091.8 connects to the preparation approach of 4-tert-butyl-4″-methoxydibenzoylmethane, which belongs to the field of fine chemical technology. It consists of the following steps: (1) Mix p-methoxyacetophenone and solvent evenly; (2) Mix p-tert-butyl methyl benzoate and solvent equally, and include 60%~ of the mass of p-methoxyacetophenone. 100% sodium methoxide or salt ethoxide, heat up to 40 ℃ ~ 100 ℃ and after that include p-methoxyacetophenone service dropwise until the mass ratio of p-methoxyacetophenone and p-tert-butyl methyl benzoate is 0.6 ~ 2.0, the dropwise enhancement is finished, and the insulation reaction proceeds; (3) After the reaction is total, the unrefined product is acquired, adjust the pH of the unrefined product to ≤ 5, liquify it after stirring, and wash it with water to different layers; (4) After the water-washed product is eliminated from the solvent, include methanol to liquify, after that decolorize with turned on carbon, repetitively add methanol, and fine-tune once again to acquire the product. The reaction molar yield of the development is high, the response conditions are light, and the reaction technique appropriates for commercial production.
Application 2. CN201810391635.7 divulges a preparation technique of avobenzone, in which a changed ZSM-5 zeolite solid acid stimulant is used to remove acetic acid, an unstable by-product, under reduced pressure without presenting a solvent. Get p-methoxyacetophenone; at the same time, usage p-toluenesulfonic acid as the driver instead of typical focused sulfuric acid to execute an esterification reaction to get p-tert-butyl benzoic acid methyl ester; after that p-methoxyacetophenone and p-tert-butyl Avobenzone is gotten from the reaction of methyl benzoate, developing a new sort of avobenzone prep work procedure.