Zhishang Chemical

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Zhishang Chemical

Osthole Supplements CAS 484-12-8

Molecular Formula: C15H16O3

Formula Weight: 244.29

ZSpharmac: Osthole Supplements Supplier

Product Name: Osthole Supplements
CAS No: 484-12-8
Purity: 99%

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Basic Info

Product Name:Osthole Supplements
Other Names:Osthole
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:1532714-185-1
Storage:Sealed in dry,2-8°C
Provide:Osthole Supplements MSDS;
Osthole Supplements COA

What is Osthole Supplements?

Osthole Supplements is a material extracted from the fruit of the yearly natural herb Cnidium chinensis of the Umbelliferae family members. Its look is yellow-green to white crystalline powder, insoluble in water and chilly petroleum ether, and quickly soluble in acetone, methanol, ethanol, chloroform, Chloroform, ethyl acetate, soluble in boiling petroleum ether, have antispasmodic, hypotensive, antiarrhythmic, immune feature enhancing as well as broad-spectrum antibacterial results. Clinically, it is mainly used to treat male impotence, scrotum moist itching, women genital irritation, cold womb inability to conceive, rheumatic arthralgia, scabies and eczema, as well as trichomonal vaginitis. Osthole Supplements can additionally be made use of as field pesticides and also fungicides. The contact action is the primary action, and the belly poisoning activity is supplemented. It passes away from exhaustion, as well as has excellent contact murder result on different parasites such as cabbage caterpillar, tea looper, cotton bollworm, beetroot armyworm and also various aphids.

Osthole Supplements Property

Melting point 83-84°C
Boiling point 347.2°C (rough estimate)
density 1.1263 (rough estimate)
refractive index 1.5570 (estimate)
storage temp. Sealed in dry,2-8°C
solubility methanol: soluble10mg/mL, clear, colorless
form powder
color white
Water Solubility 12mg/L(25 ºC)


Osthole Supplements Uses

  1. Osthole Supplements have a wide range of biological activities and are widely used in cosmetics, medicine, agriculture and other fields.
  2. Osthole Supplements have antispasmodic,
  3. Osthole Supplements has a pesticide active gene-isopentene structure, which exhibits unique insecticidal and antibacterial activities. Studies have shown that osthole not only has an effect on pests such as cabbage worms, diamondback moths, aphids, and noctuid eggs, but also has effects on plant pathogenic fungi such as cucumber powdery mildew, grape downy mildew, capsicum phytophthora, wheat scab, etc. Significant inhibitory effect.
  4. The characteristics of Osthole Supplements as botanical pesticides: safe and environmentally friendly, organic and green, with broad-spectrum, high efficiency, low toxicity, and no residue. At the same time, it also has the function of keeping green and prolonging the functional period of leaves. hypotensive, antiarrhythmic, immune function enhancing and broad-spectrum antibacterial effects.

Osthole Supplements Botanical Insecticides

Osthole Supplements is a class of natural coumarin compounds firstly extracted and isolated from Umbelliferae plants. The dry and mature fruit of Umbelliferae Cnidifolia (Fructuscnidii) has a high content, hence the name. Relevant studies have shown that Osthole Supplements also exist in a variety of other plants, mainly including Umbelliferae such as Angelica, Gudangia, and Cnidium, as well as Rutaceae such as Citrus, Champagne, Citrus, and Rutacea. In addition, it is also distributed in a few species of Asteraceae and Fabaceae.
Osthole Supplements, also known as methoxy parsvelol or parsley phenol methyl ether (osthole, Ost), its chemical name is 7-methoxy-8-prenyl coumarin, the core structure consists of benzene ring and pyran Ketone ring composition. As a member of coumarin compounds, Osthole Supplements has not only the core structure of coumarin, but also an isopentene structure, and the isopentene structure compound plays an important role in disease resistance as a plant protection element.
Osthole is a botanical insecticide. Its mode of action is mainly contact action, supplemented by stomach poisoning. died of exhaustion. The indoor activity and toxicity test shows that it has high activity against cabbage caterpillar (LD50 is 6.2258mg/kg). The field efficacy test shows that it has good control effect on cruciferous vegetable cabbage caterpillar and tea tree geometrid. The dosage for preventing and controlling cruciferous vegetable cabbage caterpillar is 4.8~7.2g/h㎡ of active ingredient (converted into 0.4% Osthole Supplements EC, the commercial volume is 80~120mL per mu); the dosage for preventing and controlling tea tree gnat is 6~7.2g of active ingredient /h㎡ (converted into 0.4% osthole emulsifiable oil and use 100~120mL per mu of land). Generally, the amount of drug solution per mu is 50~75kg, and it is sprayed evenly; the duration of effect is about 7 days. It is safe to crops within the dosage range, and no phytotoxicity has been seen.

Chemical Composition of Osthole Supplements

The main chemical components of Fructus Cnidii are coumarins and volatile oils, as well as compounds such as triterpenoids, glycosides, sugars, etc. Among them, coumarins are the main components of Fructus Cnidii to exert pharmacological effects, and have been extracted from Fructus Cnidii A total of 48 coumarins were isolated and identified, including 22 simple coumarins and 9 linear furanocoumarins. Among them, the content is relatively high, and there are 6 kinds of coumarin compounds commonly used in chemical detection and identification, namely Osthole Supplements (Osthole), imperatorin (Imperatorin), isopimpinellin (Isopimpinellin), xanthotoxin ( Xishhotoxin), Bergaptene and Isoimperatorin.
Studies have shown that Osthole Supplements, a coumarin compound in Fructus Cnidii, have a variety of biological activities, including antibacterial, anti-inflammatory, anti-tumor, anti-osteoporosis, etc., and can also be used as biological pesticides. We use osthole as an active ingredient for quality control.

About That Product:
If you need Osthole Supplements this cosmetic raw material, please contact our service personnel directly, we will provide you with high-quality products at the best price.
As an experienced Osthole Supplements manufacturer and supplier, ZSpharmac will provide Osthole Supplements raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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