Zhishang Chemical

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Zhishang Chemical

Oleyl Alcohol CAS 143-28-2

Molecular Formula: C18H36O

Formula Weight: 268.48

ZSpharmac: Oleyl Alcohol Supplier

Product Name: Oleyl Alcohol
CAS No: 143-28-2
Purity: 99%

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Basic Info

Product Name:Oleyl Alcohol
Other Names:9-Octadecen-1-ol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Almost Colorless to Yellow Viscous Liquid
EINECS No.:205-597-3
Provide:Oleyl Alcohol MSDS;
Oleyl Alcohol COA

What is Oleyl Alcohol?

Oleyl Alcohol is a long-chain fatty alcohol that is octadecyl alcohol (Z isomer) with a double bond at position 9. It acts as a nonionic surfactant and metabolite

Oleyl Alcohol Propertyz

Melting point 

0-5.0 °C (lit.)

Boiling point 

207 °C/13 mmHg (lit.)


0.849 g/mL at 25 °C (lit.)

vapor pressure 

10.64 hPa (195 °C)

refractive index 

n20/D 1.46(lit.)


>230 °F

storage temp. 



Soluble in ethanol (95%), and ether; practically insoluble in water.


Viscous Liquid




Clear almost colorless to yellow

Water Solubility 

Miscible with alcohol and ether. Slightly miscible with carbon tetrachloride. Immiscible with water.



Oleyl Alcohol Uses

  1. Oleyl Alcohol is an unsaturated fatty alcohol used as a nonionic surfactant, emulsifier, emollient and thickener in skin creams, lotions and many other cosmetic products.
  2. Oleyl Alcohol is used in the manufacture of detergents, wetting agents, defoamers, lubricants for metal cutting, plasticizers and fabric softeners. It is also used as a raw material for organic synthesis and special surfactants, and can be used to produce oil additives, cold-resistant auxiliary plasticizers, lubricants and solvents, etc.

Ecological Information for Oleyl Alcohol

Using oleyl alcohol as a chemical intermediate, vehicle lubricating substance, defoamer, co-solvent as well as likewise printing ink plasticizer, and likewise as an aesthetic moisturizer may lead to its launch to the environment with countless waste streams. Oleyl alcohol is an all-natural product in fish oil. If released to air, the estimated vapor stress at 25 ° C is 9.3X10-5 mmHg, revealing that oleyl alcohol will definitely exist in both the vapor along with bit phases of the environment. Vapor-phase oleyl alcohol breaks down in the ambience by action with photochemically produced hydroxyl radicals; this feedback has actually an estimated half-life of 4.9 hrs in air as well as 2.1 hours for radicals in the ozone air. Bit stage oleyl alcohol will be removed from the environment by wet or dry deposition. If introduced to dirt, oleyl alcohol is not anticipated to trigger based upon an approximated Koc of 1.3 X10 +4. Volatilization from wet dust surface areas is expected to be a significant destiny treatment based on an approximated Henry’s regulation constant of 4.6X10-4 atm-cu m/mole. However, adsorption to dirt is expected to undermine volatilization. A microbial study making use of pure cultures recommended that biodegradation may be a vital destiny treatment for oleyl alcohol in soil as well as water, yet no cost data were provided. If released to water, oleyl alcohol is expected to adsorb to suspended solids as well as particles based upon the estimated Koc. Volatilization from the water surface is anticipated to be a crucial destiny treatment based on the estimated Henry’s regulation constant for this material. The approximated volatilization half-lives were 8 hrs along with 7.4 days for the design river in addition to variation lake, specifically. Nevertheless, volatilization from the water surface area is anticipated to weaken the column by adsorption to put on hold solids and likewise particles in the water. The estimated volatilization half-life for the design cell is 163 days if adsorption is taken into account. An estimated BCF of 420 recommends a high bioconcentration capacity in water microbes. Hydrolysis is not anticipated to be a crucial environmental fate procedure because the substance does not have practical groups that hydrolyze under ambient problems. In work environments where oleyl alcohol is produced or used, work-related direct exposure to oleyl alcohol may develop from inhalation of vapors or contact with this substance through eyes and also skin. The general public could be revealed to oleyl alcohol through skin get in touch with throughout using aesthetic products consisting of oleyl alcohol as a visual emollient in addition to in the intake of fish.

A Novel pH-Sensitive Liposome Formulation Containing Oleyl Alcohol

The pH-sensitive liposomes are made for acid-triggered destabilization. First-generation pH-sensitive liposomes based upon the cone-shaped lipid dioleoylphosphatidylethanolamine (DOPE) have actually been shown to shed fusogenicity in the visibility of cream. Right here, we report based on egg phosphatidylcholine (PC), cholesteryl hemisuccinate (CHEMS), oleyl alcohol (OAlc) as well as additionally Tween-80 (T-80). When filled with the fluorescent probe calcein, These liposomes showed superb safety at pH 7.4 as well as also were quickly undercuted upon acidification, as revealed by calcein dequenching as well as also fragment measurement rise. Adjusting the molar percents of T-80 in addition to OAlc in the formula can tune the stability as well as pH sensitivity of these liposomes. Liposomes with better T-80 product presented higher stability but were much less at risk to acid-induced destabilization. At the same time, formulas with greater OAlc product showed better internet content launch in feedback to reduced pH. pH-triggered liposome destabilization did not create membrane layer fusion as recognized by octadecylrhodamine B chloride (R( 18 )) lipid blending. Contrasted to DOPE-based pH-sensitive liposomes, the above solutions disclosed far better retention of pH-sensitive homes in the visibility of 10% item. These liposomes were then examined for intracellular distribution of entrapped cytosine-β-D-arabinofuranoside (araC) in KB human oral cancer cells with elevated folate receptor (FR) expression. FRs boosted in numerous sorts of human swellings have been revealed to mediate the internalization of folate-derived liposomes right into acidic intracellular areas. FR-targeting OAlc-based pH-sensitive liposomes videotaping 200 mM araC revealed about 17-fold much better FR-dependent cytotoxicity in KB cells contrasted to araC supplied by FR-targeting non-pH-sensitive liposomes. These information suggest that OAlc-based pH-sensitive liposomes incorporated with FR-mediated targeting are appealing distribution autos for membrane-impermeable rehabilitations FR-targeting OAlc-based pH-sensitive liposomes taping 200 mM araC showed around 17-fold much better FR-dependent cytotoxicity in KB cells contrasted to araC supplied by FR-targeting non-pH-sensitive liposomes. These information recommend that OAlc-based pH-sensitive liposomes incorporated with FR-mediated targeting are appealing distribution vehicles for membrane-impermeable treatments. FR-targeting OAlc-based pH-sensitive liposomes capturing 200 mM araC showed about 17-fold higher FR-dependent cytotoxicity in KB cells compared to araC offered by FR-targeting non-pH-sensitive liposomes. These info suggest that OAlc-based pH-sensitive liposomes incorporated with FR-mediated targeting are encouraging delivery cars for membrane-impermeable rehabs.

About Products:
If you need Oleyl Alcohol as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
Our company as an experienced Oleyl Alcohol manufacturer and supplier,
ZSpharmac will provide Oleyl Alcohol raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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