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Zhishang Chemical

Oleuropein Solgar CAS 32619-42-4

Molecular Formula: C25H32O13

Formula Weight: 540.52

ZSpharmac: Oleuropein Solgar Supplier

Product Name: Oleuropein Solgar
CAS No: 32619-42-4
Purity: 99%

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Basic Info

Product Name:Oleuropein Solgar
Other Names:Oleuropein
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Light Beige to Dark Brown Liquid
EINECS No.:251-129-6
Storage:Inert Atmosphere,2-8°C
Provide:Oleuropein Solgar MSDS;
Oleuropein Solgar COA

What is Oleuropein Solgar?

Oleuropein Solgar, additionally called oleuropein, is a natural plant essence generally originated from the leaves of the olive tree, which comes from the evergreen tree of the family Oleaceae. High edible value, rich in top notch edible vegetable oil – olive oil, is a famous subtropical fruit tree as well as an important financial tree. Olive is broad-leaved, single-leaf opposite, with white top blossoms, 4-lobed corolla, 2 male and female, 2-chambered ovary, 2 ovules in each chamber, as well as the berry is oily and oblong. There are as numerous as 500 selections of olives, as well as concerning 140 are widely planted. China is the home town of olives and the nation with the most olives in the world. The district with the biggest circulation of olives in my nation is Fujian, and also Guangdong, Guangxi, Zhejiang, Sichuan, Taiwan and also other provinces are also grown. Nations worldwide that grow olives consist of Thailand, Vietnam, Myanmar, Laos, the Philippines, India and Malaysia. Olive has solid development capacity, dry spell resistance, as well as light-loving. It is mainly dispersed in countries along the Mediterranean Sea in Europe and California in the USA. Greece, Italy, Tunisia, as well as Spain are focused manufacturing areas. All nations on the planet are currently introduced and grown. In the 1950s, a small amount was presented into my nation, as well as it was introduced as well as grown in Gansu, Shaanxi, Sichuan, Chongqing, Fujian, Guangxi, Guangdong, Hunan and also other provinces as well as cities in the west as well as northwest of China. Initial wild olives can still be seen in the hills of Sichuan, Guizhou, and Hunan in my nation.
Olive fallen leaves mainly have Oleuropein Solgar as well as its glycosides, flavonoids and their glycosides, biflavones and their glycosides, low-molecular tannins as well as various other active ingredients, and secoiridoids are the major active components. Oleuropein is a safe secoiridoid glycoside polyphenolic substance. Secoiridoids are a class of compounds in cyclopentane monoterpene derivatives, which are created by splitting rings of iridoids and also represent only a little part of iridoids. Oleuropein Solgar is a vital phenolic secoiridoid glycoside, which widely exists in Oleaceae, Syringa, Ligustrum category, Melilotus genus and also Jasmine category and also various other plants in the family Oleaceae. Researches have actually revealed that oleuropein has antioxidant, anti-inflammatory, anti-bacterial, antiviral, anticancer, antitumor and hypoglycemic impacts, and is progressively made use of in medicine, health food, cosmetics and other sectors with wide application prospects.

Oleuropein Solgar Property

Melting point 89-90°C
alpha D20 -147° (H2O, alcohol, or acetone); D20 -127°
Boiling point 772.9±60.0 °C(Predicted)
density 1.50±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form neat
color Light Beige to Dark Brown


Pharmacological Action and Extraction Method of Oleuropein Solgar

Pharmacological Action:

According to study, Oleuropein Solgar has antiviral, antitumor, antioxidative, anti-bacterial, hypoglycemic, antihypertensive, stop coronary heart problem and atherosclerosis results. The application of oleuropein is also extensively made use of with the discovery of numerous medicinal activities. High material is mostly used in skin care items, which can protect skin cells from ultraviolet rays, efficiently preserve skin inflammation as well as elasticity, and accomplish skin care, Skin rejuvenation impact. Microherb’s 80% high-content Oleuropein Solgar is specifically developed for skin care products. It has high active components and light shade, which is very ideal for aesthetic formula layout.

Extraction Method:

Currently typically made use of Oleuropein Solgar removal approaches consist of leaching, ultrasonic-assisted extraction, microwave-assisted removal, supercritical carbon dioxide extraction, dispersion liquid-liquid micro-extraction, superheated fluid removal, low-temperature vacuum steaming purification removal, etc. Xie Pujun et al. carried out a comprehensive evaluation as well as comparison of different approaches, and also thought that the mix of ultrasonic wave and low-temperature decompression is an extraction approach appropriate for industrial manufacturing, with basic procedure, high performance, and also reduced energy consumption; Advanced analysis methods such as HPLC, GC-MS and other tools are directly utilized to understand internet analysis and also detection, which can not just boost the speed of evaluation and discovery, however likewise manage the quality of products. This is also an advancement pattern in the future research on the extraction as well as separation of natural products.

Oleuropein Solgar Nanoliposome Oral Care Application

Anti-inflammatory result
Swelling is the body’s protection reaction to stimulations. Under normal conditions, a slight inflammatory reaction is beneficial to the body. Without an inflammatory feedback, the infection can not be regulated and also the injury can not be recovered. However, severe inflammatory responses can intimidate the person’s life, and anti-inflammatory medicines need to be used to subdue the inflammatory response.
Oleuropein Solgar can properly minimize the number of leukocyte, minimize the expression of inflammatory elements, as well as advantage tissue regrowth and also repair service.
Anti-bacterial impact
Oleuropein Solgar is bactericidal against a broad range of Gram-positive and Gram-negative bacteria.
After 3 duplicated examinations, the outcomes revealed that compared to the toothpaste without oleuropein, the toothpaste consisting of oleuropein had dramatically improved antibacterial effect on Yeast albicans as well as Staphylococcus aureus.
Deal with oral disease
The average OMAS (Oral Mucositis Evaluation Range) results for various days showed that Oleuropein Solgar Nanoliposomes had the lowest standard.
Compared to the use of pure water, making use of oleuropein nanoliposomes can substantially reduce the plaque index.

Oleuropein Solgar Purification Method and Determination Method

Test Methods:

1. Dang Jianzhang as well as others identified the Oleuropein Solgar in olive leaves, and also established an HPLC content determination technique: the chromatographic column is ZORBAX Eclipse XDB-C18 (4.6 mm * 250mm, 5um), and also the mobile stage is 0.01mol.L-1 phosphoric acid solution-acetonitrile (79:21), the flow price is 0.8ml.min-1, and also the detection wavelength is 254nm.
2. Zheng Yuanyuan established a technique that makes use of the difference in the absorption residential or commercial properties of overall flavonoids and also Oleuropein Solgar in the two shade growth systems. While gauging the complete flavonoid content, the UV-VIS subtraction approach was used to indirectly gauge the Oleuropein Solgar in olive fallen leave remove. Compared to the HPLC method for determining the material of oleifera in olive leaves, it is discovered that this method has high accuracy and reliability. It is believed that this approach can change the existing HPLC approach, and this method is fast and also simple., inexpensive.

Purification Method:

1. Ye Jianzhong obtained the crude remove of Oleuropein Solgar by the warm reflux extraction process, as well as purified the AB-8 resin after testing. The optimal conditions for AB-8 material purification are: the mass concentration of the sample is 2g/L, After elution with 70% ethanol-water, the circulation rate was 3mL/min, and also the quantity of eluent was 3BV. The last pureness of oleuropein got to 47.90%, the flavonoid material was 16.4%, and also the return was 6.43%.
2. Fu Shan et al. explored the adsorption of 6 different macroporous materials to Oleuropein Solgar, as well as screened D101 macroporous adsorption material with great adsorption selectivity. Using D101 material as the adsorption product, the best adsorption problems were obtained: sample filling mass concentration 41.06 mg/mL, flow price 5mL/min, 50% ethanol option elution, eluent dose 260mL, the resin can be used continuously. After being enriched by macroporous material, the pureness of oleuropein can get to greater than 55%, and also after filtration by Sephadex gel, it can reach more than 76%.

About That Product:
If you need Oleuropein this cosmetic raw material, please contact our service personnel directly, we will provide you with high-quality products at the best price.
As an experienced Oleuropein manufacturer and supplier, ZSpharmac will provide Oleuropein raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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