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Oleamide CAS 301-02-0

Molecular Formula: C18H35NO

Formula Weight: 281.48

ZSpharmac: Oleamide Supplier

Product Name: Oleamide
CAS No: 301-02-0
Purity: 99%

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Basic Info

Product Name:Oleamide
Other Names:Oleic Acid Amide
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to off-White Neat
EINECS No.:206-103-9
Provide:Oleamide MSDS;
Oleamide COA

What is Oleamide?

Oleamide is a non-ionic surfactant, additionally called 9-octadecanoic acid amide, oleamide, white powder or flake at area temperature level, secure, insoluble in water, soluble in comfortable ethanol, ether and likewise many various other natural solvent. Improved from vegetable oil, it has special interior and also outdoors lubrication and also is relatively constant to warmth, oxygen, as well as also ultraviolet rays. It has the features of anti-adhesion, level of smoothness, smoothing, proceeding, water immune, moisture-proof, anti-sedimentation, anti-fouling, anti-static, as well as additionally diffusion. Mostly made use of as high-pressure polyethylene (LDPE) movie and its composite movie, multi-layer co-extruded film, air bag, ultra-thin movie, as well as polyvinyl chloride (PVC) calendered movie, polypropylene (PP), cast polypropylene (Slip representative, opening up representative and also antistatic agent for CPP) movie; ethylene-vinyl acetate copolymer (EVA), polyoxymethylene (POM), polycarbonate (COMPUTER), polyethylene terephthalate (PET), Polyamide () and also other material lubricating substances and release agents; PU surface therapy representative and fiber masterbatch smooth, antistatic agent; plastic surface printing (composite) ink and PE thermoplastic dipping powder anti-adhesive agent And also leveling representative, smooth brightener; Toner, color paste, lube and also dispersant of shade masterbatch; Functional opening, exceptional additive vital for smooth masterbatch: it can also be utilized as steel defense rib representative as well as Lubricants for polyolefin sheets, etc.

Oleamide Property

Melting point 70°C
Boiling point 433.3±24.0 °C(Predicted)
density 0.94 g/cm3
storage temp. -20°C
solubility Soluble in chloroform (50 mg/ml), ethanol (100 mM), DMSO (~14 mg/ml), and DMF (~14 mg/ml)
form neat
color White to off-white
Water Solubility Insoluble in water.


Oleamide Uses

1. Chemical ingredients that must be contributed to low-density polyethylene (LDPE) movie materials.
2. It is likewise a modifier of plastic ink.
3. Oleamide is additionally made use of as polypropylene (PP); polystyrene (GPPS); phenolic (PF) resin and other lubricants; antistatic representative; anti-caking additive.
4. Oleamide can be used as a lubricant for polyethylene, polypropylene, synthetic fiber as well as other focused shade masterbatches as well as cable (insulation) materials; film release representative.
5. Oleamide is used as polypropylene (securing gasket) pushing sheet; additive for high-efficiency heat-sealing sheets and sealing products.
6. In addition to metal safety representative; stabilizer for melamine formaldehyde tableware items; antifreeze additive for brake lubricating oil; lubricant for paint and also diffusion stabilizer for aluminized paint; oil drilling help.

Synthesis of Oleamide

图1 油酸酰胺的合成路线[2]。

Approach 1: Oleic acid (25g, 74% pureness) was billed right into a 250ml round base flask, and also strong urea beads (22g) were billed into the exact same flask together with tetrabutyl titanate (0.25 g). The blend was stirred for one minute with a magnetic stirrer in a 900W microwave dental caries. The heating program raised the temperature from ambient to 190 ° C within 5 min and also held at 190 ° C for an extra 25 min. During home heating, urea will certainly melt above 135 ° C and begin to decompose at 150 ° C launching NH3 and carbon dioxide. The acid variety of the response item was identified to be around 10, as well as the conversion of oleic acid to the reaction product was about 95% based on the acid number. The cooled down reaction product from Instance 1 was blended with chloroform as well as any type of unreacted urea was filtered from the reaction product. The chloroform fraction was then evaporated on a rotating evaporator to manage Oleamide. The yield of Oleamide is 92%, melting point 74 ° C. The artificial course is shown in Figure 1.

Technique 2: Consider 25 grams of reactant (Z)-octadecenoic acid. Place it right into a 500mL four-port response vessel. The mixture was dried out at 280 ° C for 16 hrs. Include 350 mL of dichloroethylene (CH2Cl2) to the reaction combination. Stirring was continued for thirty minutes and the blend was cooled to 0-5 ° C. Twenty-two milliliters of oxalyl chloride was added in small amounts to the reaction blend. Raise the temperature over 5 ° C. The reaction combination was reacted at area temperature level for 4 hrs. Full the reaction. Location the combination under vacuum cleaner. Excess CH2Cl2 and also oxalyl chloride were vaporized. The reaction vessel was restored with fresh CH2Cl2 (250 mL). Refrigerate the option to 0-5 ° C. A stream of ammonia [NH3(g)] was contributed to the response vessel for 1 hour. The mixture was evaporated in vacuo to completely eliminate excess CH2Cl2. Ethyl acetate (500 mL) was added to dissolve the deposit. After rinsing the remedy with 300 mL of distilled water, the ethyl acetate layer was separated. Laundry the ethyl acetate layer with 200 mL of saturated sodium bicarbonate (NaHCO3) solution and adequate distilled water to get a neutral pH. The remedy was dehydrated with sufficient anhydrous magnesium sulfate. Filter the service. The filtrate was vaporized in vacuo to completely remove ethyl acetate. The crude item was detoxified on a C-18 column chromatography (i.d.x l=1.5 x 24 centimeters) utilizing a mixed mobile phase (acetonitrile/HO=80:20) operating at 3 mL/min to obtain the highly pure substance Oleamide. The artificial path is displayed in Figure 1.

Oleamide Slip Agent

At present, the common types of slip agents in China include amides (Oleamide and erucamide), soaps (calcium stearate, etc.) and organic silicon (silicone). Organosilicon is liquid, it is inconvenient to add and use, and the price is expensive. There is no professional manufacturer in China, so it is difficult to popularize and apply. Although soap products are cheap, the effect is not ideal, and the addition amount is large, so it cannot be used basically in medium and high-end products. Oleic acid amide and erucic acid amide are two kinds of slippery agents, moderate price, obvious effect, very little added amount (0.05% ~ 0.3%), non-toxic (approved by FDA), wide range of use, and have a wide range of promotion and application prospects .
Adding 0.05% to 0.3% Oleamide to the low-density polyethylene film material can not only improve the antistatic and lubricating properties, but also improve the moisture-proof performance, significantly reduce the friction coefficient and adhesion resistance, and significantly improve the blown film (extrusion) It can effectively prevent the bonding between the films and the agglomeration between the pellets, increase the smoothness of the film surface, prevent the accumulation of dust on the surface of the product, and produce a very smooth plastic product.
Adding Oleamide (0.05%) to polyolefin cable materials and all-plastic communication cable materials can reduce the friction coefficient from 0.70 to 0.16. At the same time, it can also change its coloring and carbon black dispersion, and realize high-speed cable pellets. Extruded to improve the smoothness of the inner wall of the cable jacket tube.
Adding 2-5 oleic acid amide to polyamide plastic ink can improve printing performance and ink lubricity, enhance water resistance, enhance scratch resistance, and anti-fouling (fouling caused by wet ink) , Wear resistance. In addition, it can also improve the extension and adhesion of the ink on the surface of the printed matter, making the imprint clear and bright in color.

About Products:
If you need Oleamide as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Oleamide manufacturer and supplier, ZSpharmac will provide Oleamide raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Oleamide Quotation