Zhishang Chemical

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Zhishang Chemical

Octyl P-Methoxycinnamate CAS 5466-77-3

Molecular Formula: C18H26O3

Formula Weight: 290.4

ZSpharmac: Octyl P-Methoxycinnamate Cosmetic Raw Material Suppliers

Product Name: Octyl P-Methoxycinnamate
CAS No: 5466-77-3
Purity: 99%

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Basic Info

Product Name:Octyl P-Methoxycinnamate
Other Names:Octyl Methoxycinnamate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless to Yellow Liquid
EINECS No.:226-775-7
Provide:Octyl P-Methoxycinnamate MSDS;
Octyl P-Methoxycinnamate COA

What is Octyl P-Methoxycinnamate?

Octyl p-methoxycinnamate is a frequently utilized sun block, anti-aging representative and UV absorber. According to appropriate research studies, p-octyl methoxycinnamate has mutagenic, teratogenic and developing poisoning to the body, and has possible persistent health and wellness impacts.

Octyl P-Methoxycinnamate Property

Melting point <-25℃
Boiling point 198-200°C
density 1.009
refractive index 1.543-1.547
Fp 193°C
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Liquid
color Clear colorless to yellow
Water Solubility <0.1 g/100 mL at 27 ºC


Octyl P-Methoxycinnamate Applications

Application 1.
CN201910955854.8 discloses a pediatric injury spray and a prep work technique thereof. The pediatric trauma spray is made up of 5-chloro-7-(3-hydroxy-propoxy)-3-nitromethyl-3H-benzo [c] [1,2] oxaborole -Made from 1-alcohol, borneol, Octyl P-Methoxycinnamate, isopropyl alcohol, methyl ethyl ketone, Tween 80, disodium edetate and cleansed water. It is in the form of a remedy and has excellent stimulating impact on pediatric distressing wounds, specifically It is the feature of recovery wounds from hemorrhagic injury.

Application 2.
CN201210507572.X reveals an emulsifier-free sun block. The sun block representative of today innovation includes octocrylene, Octyl P-Methoxycinnamate, avobenzone and original film loose ester to create a UV defense basic system, and is supplemented with isododecane/polydimethylsiloxane/vinyl polydiethylene Methyl silicone cross-linked compound, grapefruit crucial oil, benzyl alcohol, silica silylate, inca fruit oil, argan tree kernel oil and various other inactive active ingredients are prepared in proportions to prepare a new sun block formula. The UV protection fundamental system is included in other cosmetic preparation service providers to give UV power resistance. This sun block does not include emulsifiers and has little skin irritability. It can not just efficiently obstruct the damage of ultraviolet rays to the skin, but likewise has water resistant impact. It has good compatibility with structure and other facial skin care products, and has a silky texture. Refreshing, non-greasy, all-natural looking finish. Sun block products with SPF30 ~ SPF50 are preferable for Asian individuals and have wide market leads.

Application 3.
CN201510735753.1 divulges a preparation approach of sun block consisting of microcapsules with post-sun fixing function. Initially, maltodextrin, periodontal arabic, hydroxyethyl cellulose, coconut oil, sea buckthorn oil, jojoba wax, squalane, vitamins E. Witch hazel alcohol remove, purslane alcohol essence, paeoniflorin, eco-friendly tea alcohol extract, L-cysteine and Span 80 are used as raw materials to prepare microcapsules with post-sun repair work feature; and afterwards the microcapsules are With coconut oil, lanolin, ethanol, zinc oxide, titanium dioxide, Octyl P-Methoxycinnamate, butylmethoxydibenzoylmethane, isooctyl 2-cyano-3,3-diphenylacrylate, vitamin E, deionized Water, xanthan gum tissue and Period 20 are used with each other as resources to prepare the sun block. The present creation utilizes microcapsule innovation to install post-sun repair work ingredients and include them to the sun block, to ensure that the sunscreen can exert twin effects of sunlight security and post-sun repair service, effectively preventing undesirable cross-competition brought on by the conjunction of both.

Octyl P-Methoxycinnamate Detection Method

An approach for identifying Octyl P-Methoxycinnamate in textiles, including the complying with actions:
The very first step is to take a sample from the textile: use stainless-steel scissors to cut the sample into tiny rectangular items with a diagonal length of no greater than 5mm.

In the second step, evaluate 1.0 g of the chopped sample and area it in a 40mL container (reaction tube in this example), then add 10mL methanol to the container, position the container in an ultrasonic cleaner for ultrasonic extraction for thirty minutes. The ultrasonic frequency is 50kHz, the ultrasonic temperature is 25 ° C, and the removal liquid is gotten;

In the third step, filter the removal remedy obtained in the second action to obtain the test service. Especially, utilize a 0.45 μm organic filter membrane layer to filter 1 mL of the removal solution into an example bottle;

The 4th step is to examine the examination option acquired in the 3rd action using ultra-high efficiency fluid chromatography tandem mass spectrometry (UPLC-MSMS). Among them, the model of the ultra-high performance fluid chromatography tandem mass spectrometer is Seas Acquity H Course+Xevo TQD, the version of the chromatographic column is Waters BEH C18 column, and the spec of the chromatographic column is 50mm × 2.1 mm × 1.7 μm (the column length is 50mm, the fragment dimension of the filler is 1.7 μm, and the inner size of the column is 2.1 mm).

The examination problems of the ultra-high efficiency liquid chromatography tandem mass spectrometer are: the injection quantity is 5 microliters; the circulation price is 0.2 mL/min; the elution process takes on the gradient elution program; the procurement mode is the favorable ion MRM mode; the capillary voltage is 0.5 KV; the desolvent gas flow rate is 900L/h; the desolvent gas temperature level is 400 ° C; the forerunner ion is 291.1, the cone voltage is 15V, the quantifier ion is 179.1, the crash power is 8V; the qualifier ion is 161.1, the accident power is 15V; measurable ion shift 291.1 → 179.1, qualitative ion change 291.1 → 161.1.

Synthesis Method of Octyl P-Methoxycinnamate

In a three-necked flask furnished with a stirrer, thermostat and reflux condenser, include 12.1 mL (0.1 mol) of p-methoxybenzaldehyde, 12.4 g of malonic acid and 11.3 mL of pyridine, warmth and mix to entirely liquify the solid. After stopping the reaction, put the action selection right into a small beaker, permit it stand and allow it elegant normally, crystals will speed up, recrystallize, neat, filter and completely dry to obtain p-methoxycinnamic acid.

Include 8.9 g (0.05 mol) of p-methoxycinnamic acid to a four-necked flask equipped with a stirrer, thermostat, reflux condenser and water separator, and gradually include 13.0 mL of isooctyl alcohol and 30.0 mL of benzene while blending. Warm over reduced warm and mix to liquify the solids. After the solid is liquified, gradually include 0.2 mL of focused sulfuric acid dropwise in collections, slowly raise the temperature, and protect constant mixing till the color of the liquid begins to turn yellow. When the temperature degree reaches 85 ° C, begin refluxing and preserve reflux for 5 hours. After the product in the bottle is clarified, keep reflux for one more 1 hour up until say goodbye to water is produced and the response finishes. Afterwards outstanding to room temperature level, contain an appropriate amount of NaHCO3 saturated selection to lower the results of, let it stand to split the natural layer, add anhydrous calcium chloride to dry the all-natural layer, separate the liquids, and boil down under decreased stress to obtain a light yellow fluid of the 250 ° C (0.009 1 MPa) fraction, which is It is isooctyl p-methoxycinnamate.

About Products:
If you need the cosmetic raw material Octyl P-Methoxycinnamate, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Octyl P-Methoxycinnamate manufacturer and supplier, our company, ZSpharmac will provide Octyl P-Methoxycinnamate raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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