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Octadecyltrimethylammonium Chloride CAS 112-03-8

Molecular Formula: C21H46ClN

Formula Weight: 348.06

ZSpharmac: Octadecyltrimethylammonium Chloride Supplier

Product Name: Octadecyltrimethylammonium Chloride
CAS No: 112-03-8
Purity: 99%

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Basic Info

Product Name:Octadecyltrimethylammonium Chloride
Other Names:Trimethylstearylammonium Chloride
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder to Crystal
EINECS No.:203-929-1
Storage:Inert Atmosphere,Room Temperature
Provide:Octadecyltrimethylammonium Chloride MSDS;
Octadecyltrimethylammonium Chloride COA

What is Octadecyltrimethylammonium Chloride?

Octadecyltrimethylammonium chloride has excellent compatibility with cationic, nonionic as well as amphoteric surfactants, has superb penetration, gentleness, emulsification, antistatic, biodegradability and bactericidal residential properties, as well as excellent chemical stability. Commonly used in hair conditioner, fabric softener, fiber antistatic representative, silicone oil emulsifier, asphalt emulsifier, natural bentonite modifier, anti-bacterial, biopharmaceutical industry protein flocculant as well as water therapy flocculant, and so on.

Octadecyltrimethylammonium Chloride Property

Boiling point 249℃[at 101 325 Pa]
density 0.91[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. Inert atmosphere,Room Temperature
form powder to crystal
color White
PH5.5-8.5 (20℃, 0.05% in H2O)
Water Solubility Soluble in water 1.759 mg/L @ 25°C.


Octadecyltrimethylammonium Chloride Uses

  1. Octadecyltrimethylammonium chloride is made use of as antistatic representative for fabric fibers, hair conditioner, emulsifier for asphalt, rubber as well as silicone oil. And also commonly used in disinfectant.
  2. Octadecyltrimethylammonium chloride is made use of as a fabric softener to make fibers bulky and also soft to the touch. It is also made use of as a raw material for asphalt emulsification as well as hair conditioner.
  3. Octadecyltrimethylammonium chloride is used as a cationic surfactant, widely utilized in asphalt emulsification as well as water resistant layer emulsification, silicone oil emulsification, hair conditioner cosmetic emulsification conditioning, soft and antistatic textile fibers, natural bentonite alteration, biopharmaceuticals Industrial protein flocculation and water therapy flocculation, glass fiber soft handling, anti-burn treatment representative for nylon parachute surface area, as well as bactericide as well as disinfectant, etc.

Preparation of Octadecyltrimethylammonium Chloride

A kind of preparation technology of high stability octadecyl trimethyl ammonium chloride comprises the steps:

S1. Add dimethyloctadecylamine, deionized water and ethanol to the reaction kettle in sequence, raise the temperature of the reaction kettle to 55°C, stir evenly, the stirring speed is 300 rpm, and the stirring time is 25 minutes;

S2. Slowly add methyl chloride to the reaction kettle, the mass ratio of dimethyl octadecyl amine, deionized water, ethanol and methyl chloride is 4:1:1:1, stir evenly after adding, adjust the reaction The temperature of the kettle is 60°C, the pressure is less than 0.2MPa, and the stirring is continued, the stirring speed is 400 rpm, and the stirring time is 1.5h;

S3. When the pressure in the reaction kettle is reduced to 0.03 MPa, the reaction is over, vacuumize, and add liquid caustic soda, ethanol and hydrogen peroxide in sequence, the mass ratio of liquid caustic soda, ethanol and hydrogen peroxide is 8:4:1, stir for 20 minutes and then take samples for detection;

S4. According to the test results, if the color is darker, add 0.5kg hydrogen peroxide to the reactor; if the content of free amine and ammonium salt is greater than 1.5%, add methyl chloride; if the pH is lower than 6.5, add 1.8Kg liquid Alkali and 1.8Kg ethanol;

S5. After the temperature of the reaction kettle is lowered to below 60°C, the product is taken out and filled.

Improved Ready Biodegradability Test of Aliphatic Amine Derivatives

This research study assessed the biodegradation potential of different fatty amine by-products checked according to OECD biodegradability guidelines. In these trials, various strategies were utilized to lower poisoning and also boost the bioavailability of fatty amine by-products. Alkyl 1,3-diaminopropane as well as octadecyltrimethylammonium chloride are toxic to microorganisms at focus utilized in OECD prepared biodegradability tests. The focus of these fatty amine by-products in the aqueous phase can be decreased by reacting humic acid or lignosulfonic acid with the by-products or by including silica gel to the examination container. Making use of these non-biodegradable substances, tallow-1,3-diaminopropane and octadecyltrimethylammonium chloride, examination results for ready biodegradation were acquired. Because of the restricted bioavailability of this substance, it is virtually difficult to demonstrate the fast biodegradability of water-insoluble dioctadecylamine under recommended typical problems. However, easily offered biodegradability results can be acquired by utilizing very reduced first test substance focus and introducing natural phases. The materials of the bottles utilized to analyze the biodegradability of dioctadecylamine were constantly combined. The false unfavorable biodegradability results gotten with the fatty amine derivatives studied were the outcome of poisonous impacts and/or restricted bioavailability. Hence, the investigated accessories enhance off-the-shelf biodegradability examinations. Ready-to-use biodegradability outcomes are gotten by utilizing really low first test substance focus as well as introducing the natural phase. The components of the bottles made use of to examine the biodegradability of dioctadecylamine were constantly combined. The false adverse biodegradability results acquired with the fatty amine by-products studied were the outcome of poisonous results and/or limited bioavailability. Hence, the explored accessories boost off-the-shelf biodegradability tests. Ready-to-use biodegradability results are obtained by utilizing very reduced first test substance concentrations and presenting the organic phase. The components of the bottles made use of to analyze the biodegradability of dioctadecylamine were constantly mixed. The incorrect unfavorable biodegradability outcomes obtained with the fatty amine derivatives studied were the result of toxic results and/or restricted bioavailability. Hence, the examined auxiliaries enhance off-the-shelf biodegradability examinations.

About Products:
If you need Octadecyltrimethylammonium Chloride, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Octadecyltrimethylammonium Chloride manufacturer and supplier, ZSpharmac will provide Octadecyltrimethylammonium Chloride raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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