Zhishang Chemical

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Zhishang Chemical

Nerol CAS 106-25-2

Molecular Formula: C10H18O

Formula Weight: 154.25

ZSpharmac: Nerol Supplement

Product Name: Nerol
CAS No: 106-25-2
Purity: 99%

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Basic Info

Product Name:Nerol
Other Names:Nerol, 97%
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Colorless to Almost Colorless Liquid
EINECS No.:203-378-7
Provide:Nerol MSDS;
Nerol COA

What is Nerol?

Naturally present in neroli oil, rose oil, etc., it can also be obtained by the action of geraniol and hydroiodic acid. Nerol and geraniol are isomers, all essential oils containing geraniol often contain nerol at the same time, but the ratio is different. The ratios of Nerol and Geraniol in Nerol produced by different companies are different, so the aroma is also different.

Nerol is a monoterpene alcohol. The trans isomer of geraniol. Colorless liquid. Has aromas of rose and orange blossom, softer and more graceful than geraniol. Density 0.877-0.891. The melting point is lower than -1.5°C. Boiling point 226-227℃. Refractive index 1.462. Exist in neroli oil, rose oil, etc.

Nerol Property

Melting point 

<-15 °C

Boiling point 

103-105 °C/9 mmHg (lit.)


0.876 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.474(lit.)


226 °F

storage temp. 



absolute ethanol: soluble(lit.)


Nerol Uses

  1. Nerol is an edible spice that is permitted to be utilized in GB 2760-1996. Mostly used to prepare raspberry, strawberry and also citrus and other fruit flavors.
  2. Nerol is the primary flavor in the prep work of orange bloom, climbed as well as magnolia essences. It is also typically utilized in hyacinth, gardenia osmanthus, acacia and also various other taste solutions. Its rubus-strawberry fragrance effect is generally used in food tastes.
  3. Nerol is an edible flavor regulated by GB2760-86 in my nation. The item is likewise utilized to formulate day-to-day cosmetic significances, such as violet, orange bloom, jasmine, lily of the valley, magnolia, clove and also various other floral cosmetic significances.
  4. Nerol is widely used in orange blossom, climbed, jasmine, tuberose and other flower-flavored day-to-day chemical flavors and raspberry, grass mold and mildew flavored edible flavors, as well as can also be made into ester flavors.

Made by Nerol

1. Make geraniol react with hydroiodic acid, remove excess hydroiodic acid with alkali, obtain nerol mixed with geraniol, and then carry out steam distillation or vacuum distillation to obtain the finished product of nerol.

2. Using neroli oil as raw material, first fractionate to remove terpenes and linalool, take the primary alcohol fraction to esterify into phthalates, purify and saponify to obtain a mixture of geraniol and nerol, add lead chloride Geraniol was removed, and the residue was separated by the above method to obtain nerol.

3. It is obtained by reducing citral in aluminum isopropoxide-isopropanol solution and then separating it.

4. Heating esterification with linalool in the presence of acetic anhydride-sodium acetate, and saponification to obtain a mixture of geraniol and nerol, which is separated by the above method.

The Effect of Nerol on Acetaminophen

Nerol is a monoterpene that evidently has several organic activities, consisting of anti-oxidant, antimicrobial, antispasmodic, anthelmintic, as well as antiarrhythmic. This study intended to evaluate its hepatoprotective impact on paracetamol-induced hepatotoxicity in a rat version. Five teams of rats (n = 7) were orally (daily) with 0.05% Tween 80 (lorry), paracetamol 640 mg/kg (unfavorable control), 50 mg/kg silymarin (positive control) liquified in 0.9% NaCl remedy ), or nerol (50 and 100 mg/kg) for 14 days, complied with by paracetamol (PCM) to generate hepatotoxicity. Blood examples and livers from animals were gathered for biochemical as well as tiny analysis. Histological searchings for recommended that acetaminophen generated lymphocytic infiltration as well as significant necrosis, whereas upkeep of regular liver framework was observed in the silymarin and nerol-pretreated teams. Rats pretreated with nerol significantly as well as dose-dependently minimized the animals’ pens of hepatotoxicity. 100 mg/kg nerol significantly turned around acetaminophen-induced changes including liver enzymes, plasma proteins, antioxidant enzymes and also product bilirubin, lipid peroxidation (LPO) and also cholesterol [eg, total cholesterol] (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c)] degrees of pets. To conclude, nerol put in substantial hepatoprotective activity in rats in a dose-dependent way.

Ecological Information of Nerol

The production as well as use of nerol as a flavoring component, an intermediate in the synthesis of various other flavor chemicals, as well as a flavor compound in food may cause its launch right into the atmosphere with numerous waste streams. Its usage as a scent active ingredient in perfumes and family items will cause its direct release right into the atmosphere. Nerol has been determined as an element of cigarette smoke. Nerol exists in small amounts in several essential oils and also is constantly accompanied by geraniol. Nerol has been spotted in a variety of plants and varieties. If released right into air, an extrapolated vapour pressure of 0.03 mm Hg at 25 ° C indicates that nerol will just exist in the ambience as a vapour. Gas-phase nerol is weakened in the environment by reaction with photochemically generated hydroxyl radicals; the half-life of this response in air is approximated to be 2.1 hrs. Nerol is likewise degraded in the environment by reaction with ozone and nitrate. The half-lives for the response with ozone and nitrate are approximated to be 19 mins and also 4 mins, respectively. Nitrate_Free radicals are the dominant atmospheric oxidants at night in a lot of atmospheric atmospheres, therefore, nighttime degradation seems the leading fate process for nerol. If launched into dirt, nerol is anticipated to have actually high wheelchair based upon an approximated Koc of 94. Based upon the approximated Henry’s Law constant of 1.2X10-5 atm-cu m/, volatilization from damp soil surface areas is anticipated to be a vital destiny process mole. Also at conventional temperature level and stress, the ambient vapor stress is low, however the odor can still be smelled; for that reason, nerol might vaporize from completely dry dirt. 2 evaluating tests located the mix of nerol as well as geraniol to be easily eco-friendly after 28 days as well as 15 days, based upon 100% degradation. If launched into water, nerol is not expected to adsorb right into suspended solids as well as debris based on the approximated Koc. Utilizing the OECD 301D examination with river water inoculum, 80% academic body was achieved within 4 weeks, indicating that biodegradation is a vital ecological destiny process. Dissipation from the water surface is anticipated according to the estimated Henry’s legislation constant for the substance. The estimated volatilization half-lives for the version river as well as version lake are 4.1 days and also 34 days, respectively. An estimated BCF of 90 shows a modest potential for bioconcentration in water microorganisms. Hydrolysis is not expected to be a vital ecological destiny process due to the fact that this compound does not have functional teams to hydrolyze under ambient conditions. Photooxidation may happen in surface water subjected to sunshine. Occupational exposure to nerol can happen through breathing and also facial direct exposure to this substance in workplaces where nerol is created or utilized. Monitoring and use information suggest that the basic populace may be subjected to this nerol-containing customer item with inhalation of ambient air, consumption of food, as well as skin.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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