Zhishang Chemical

Welcome to Zhishang Chemical      +86-176 5311 3209     Simon@sdzschem.com

Zhishang Chemical

Neohesperidin CAS 13241-33-3

Molecular Formula: C28H34O15

Formula Weight: 610.56

ZSpharmac: Neohesperidin Supplier

Facebook
Twitter
LinkedIn
Pinterest
WhatsApp
Email
Product Name: Neohesperidin
CAS No: 13241-33-3
Purity: 99%

Navigation Bar

Basic Info

Product Name:Neohesperidin
Other Names:Neohesperidin HPLC 96% Min
CAS:13241-33-3
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Neat
EINECS No.:236-216-9
Storage:Sealed in Dry,2-8°C
Provide:Neohesperidin MSDS;
Neohesperidin COA

What is Neohesperidin?

Neohesperidin is a flavanone glycoside discovered in citrus fruits. Its aglycone type is called hesperetin.

Neohesperidin Property

Melting point 239-243°C
Boiling point 933.7±65.0 °C(Predicted)
density 1.65±0.1 g/cm3(Predicted)
vapor pressure 0Pa at 20℃
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly), Pyridine (Slightly)
pka7.14±0.40(Predicted)
form neat
color White to Off-White
Water Solubility 3.98mg/L at 20℃

 

Neohesperidin Uses

  1. Neohesperidin is a brand-new all-natural dietary sugar drawn out from Citrus aurantium.ruit juice, fruit a glass of a glass of wine, beverage, bread as well as pharmaceutical formula, especially appropriate as food for diabetic clients.

Neohesperidin in Vitro Studies

Neohesperidin, a flavonoid glycoside located in citrus fruits, is an anti-oxidant. In the 1,1-diphenyl-2-picryldydrazyl (DPPH) totally free extreme scavenging test, Neohesperidin serves as an antioxidant with an IC50 of 22.31 μg/ ml. Neohesperidin (50 mg/kg) dramatically inhibits HCl/ethanol-induced stomach damages and boosts mucus content. In pylorus-ligated rats, neohesperidin (50 mg/kg) substantially reduced stomach secretions as well as additionally stomach acid production, along with increased pH. Moreover, Neohesperidin hinders the growth of Caco-2, CEM/ADR5000 as well as additionally CCRF-CEM leukemia cells with IC50 worths of 0.17, 0.17 and also 0.12 mM, specifically.

Various Research Progress of Neohesperidin

Hesperetin 7-O-neohesperidoside, a well-known flavanone glycoside widely found in citrus fruits, possesses various biological activities and has potential applications ranging from food ingredients to therapeutics. The aim of this manuscript is to provide a comprehensive overview of the chemical, biosynthetic, and pharmacokinetic profiles of neohesperidin, as well as its therapeutic effects and mechanisms on underlying diseases. This literature review covers the wide range of pharmacological responses elicited by neohesperidin, including neuroprotective, anti-inflammatory, antidiabetic, antibacterial, and anticancer activities, with a focus on the mechanisms of these pharmacological responses. In addition, compounds osteoporosis, anti-ulcer, cardioprotective and hepatoprotective actions were outlined. This review includes a detailed description of the biosynthesis, biopharmacokinetics, toxicology, and controlled release of neohesperidin. Neohesperidin exhibits broad therapeutic and biological activities in the treatment of various complex diseases, including neurodegenerative diseases, hepatic heart diseases, cancer, diabetes, obesity, infectious diseases, allergic diseases, and inflammatory diseases. Neohesperidin is a promising therapeutic candidate for the treatment of various diseases with complex etiology. However, further in vivo and in vitro mechanistic studies are needed to confirm the safety, bioavailability, and toxicity profile of neohesperidin before clinical trials. This review includes a detailed description of the biosynthesis, biopharmacokinetics, toxicology, and controlled release of neohesperidin. Neohesperidin exhibits broad therapeutic and biological activities in the treatment of various complex diseases, including neurodegenerative diseases, hepatic heart diseases, cancer, diabetes, obesity, infectious diseases, allergic diseases, and inflammatory diseases. Neohesperidin is a promising therapeutic candidate for the treatment of various diseases with complex etiology. However, further in vivo and in vitro mechanistic studies are needed to confirm the safety, bioavailability, and toxicity profile of neohesperidin before clinical trials. This review includes a detailed description of the biosynthesis, biopharmacokinetics, toxicology, and controlled release of neohesperidin. Neohesperidin exhibits broad therapeutic and biological activities in the treatment of various complex diseases, including neurodegenerative diseases, hepatic heart diseases, cancer, diabetes, obesity, infectious diseases, allergic diseases, and inflammatory diseases. Neohesperidin is a promising therapeutic candidate for the treatment of various diseases with complex etiology. However, further in vivo and in vitro mechanistic studies are needed to confirm the safety, bioavailability, and toxicity profile of neohesperidin before clinical trials. Neohesperidin exhibits broad therapeutic and biological activities in the treatment of various complex diseases, including neurodegenerative diseases, hepatic heart diseases, cancer, diabetes, obesity, infectious diseases, allergic diseases, and inflammatory diseases. Neohesperidin is a promising therapeutic candidate for the treatment of various diseases with complex etiology. However, further in vivo and in vitro mechanistic studies are needed to confirm the safety, bioavailability, and toxicity profile of neohesperidin before clinical trials. Neohesperidin exhibits broad therapeutic and biological activities in the treatment of various complex diseases, including neurodegenerative diseases, hepatic heart diseases, cancer, diabetes, obesity, infectious diseases, allergic diseases, and inflammatory diseases. Neohesperidin is a promising therapeutic candidate for the treatment of various diseases with complex etiology. However, further in vivo and in vitro mechanistic studies are needed to confirm the safety, bioavailability, and toxicity profile of neohesperidin before clinical trials. Neohesperidin is a promising therapeutic candidate for the treatment of various diseases with complex etiology. However, further in vivo and in vitro mechanistic studies are needed to confirm the safety, bioavailability, and toxicity profile of neohesperidin before clinical trials. Neohesperidin is a promising therapeutic candidate for the treatment of various diseases with complex etiology. However, further in vivo and in vitro mechanistic studies are needed to confirm the safety, bioavailability, and toxicity profile of neohesperidin before clinical trials.

About Products:
If you need Neohesperidin, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Neohesperidin manufacturer and supplier, ZSpharmac will provide Neohesperidin raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Neohesperidin Quotation