Zhishang Chemical

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Zhishang Chemical

Natural Tocopherols CAS 1406-18-4

Molecular Formula: C29H50O2

Formula Weight: 430.71

ZSpharmac: Natural Tocopherols Supplement

Product Name: Natural Tocopherols
CAS No: 1406-18-4
Purity: 99%

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Basic Info

Product Name:Natural Tocopherols
Other Names:Tocopherol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Yellow Viscous Liquid
EINECS No.:215-798-8
Provide:Natural Tocopherols MSDS;
Natural Tocopherols COA

What is Natural Tocopherols?

Natural Tocopherols are also known as vitamin E. In natural vitamin E, it is known that there are 7 isomers, and there are 4 common ones, namely α-, β-, γ-, δ-, commonly referred to as vitamin E refers to α-type. The α-type has the highest activity and the δ-type has the lowest activity.
The α-form has three optical isomers. The synthetic product is the dl-body. Light yellow viscous oily transparent liquid. Naturally present in vegetable oils. The relative molecular mass is 430.69. Relative density 0.950 (25 ℃). Melting point 2 ~ 3 ℃. Boiling point 350°C (decomposition), 140°C (0.800×103Pa~1.333×103Pa). Refractive index 1.5045 (25°C). Insoluble in water, soluble in ethanol, ether, acetone, chloroform and oil. In the absence of air, it is stable to heat and alkali. It has no effect with acid below 100 °C, but is easily oxidized. It can be oxidized to quinone in the air, light or chemical reagents. This effect will be accelerated in the presence of iron salts and silver salts. Oral LD5010000mg/kg for rats.
Natural Tocopherols is a solid anti-oxidant that can effectively avoid the rancidity of fats in food as well as digestive system tract, as well as protect cells from unsafe compounds generated by the oxidation of unsaturated fats. Vitamin E is a superb totally free radical scavenger that protects biofilms from free extreme assault as well as is a reliable anti-aging nutrient. This item can boost body resistance; maintain the integrity of red cell and advertise the biosynthesis of red blood cells; it is a vital marketer of cellular respiration, which can shield lung cells from air contamination; avoid cardiovascular disease.

Natural Tocopherols Property

Melting point 292 °C
storage temp. 0-6°C


Natural Tocopherols Uses

Natural Tocopherols vitamin E consists of two sorts of tocopherols and also tocotrienols, a total amount of 8 substances, namely alpha, beta, gamma, delta tocopherols as well as alpha, beta, gamma, delta tocotrienols.

Vitamin E is used as medicine and has good medical value in preventing arteriosclerosis, anemia, liver disease, cancer, etc.; as an animal feed additive, it can improve reproductive capacity; in food, it is used as an anti-inflammatory agent for instant noodles, margarine, milk powder, oil, etc. Oxidant, can also be used in conjunction with vitamin A, vitamin A fatty acid ester, etc.

Natural Tocopherols Physiological Function

1. anti-oxidation
Natural Tocopherols is an important antioxidant in the non-enzymatic antioxidant system, which can scavenge free radicals in the body and block the chain reaction caused by them, preventing polyunsaturated fatty acids, cytoskeleton and lipoproteins in biofilms (including cell membranes, organelle membranes) and lipoproteins. The sulfhydryl groups of other proteins are attacked by free radicals and oxidants.

Vitamin E, vitamin C and β-carotene have synergistic and complementary effects of antioxidants. When the oxygen partial pressure is low, β-carotene can restore the vitamin E combined with free radicals; when the oxygen partial pressure is high, the tocopherol free radicals react with vitamin C on the surface of the biofilm to make the tocopherol Free radicals can be reduced to tocopherols. Vitamin E is mainly localized in cell membranes. Selenium and vitamin E also have synergistic antioxidant effects.

2. anti-atherosclerosis
Sufficient Natural Tocopherols can inhibit the peroxidation of cell membrane lipids, increase the antioxidant capacity of LDL-C, reduce the production of Ox-LDL, and protect LDL-C from oxidation. Vitamin E also inhibits platelet aggregation on the surface of blood vessels and protects the vascular endothelium, so it is considered to have the effect of preventing atherosclerosis and cardiovascular diseases.

3. Effects on immune function
Natural Tocopherols are important for maintaining normal immune function, especially the function of T lymphocytes. Supplementation of vitamin E in the elderly can increase the positive rate of delayed allergic skin test and enhance the activity of lymphocyte transformation test.

4. Effects on embryonic development and reproduction
No evidence has been found for Natural Tocopherols on human reproduction. However, during pregnancy, the requirement of vitamin E increases with the increase of gestational months; it is also found that when the pregnancy is abnormal, the plasma concentration of tocopherol in the corresponding gestational month is lower than that of normal pregnant women. Therefore, pregnant women can supplement small doses (50mg/d) of vitamin E.

5. Protective effects on nervous system and skeletal muscle
Vitamin E protects the nervous system, skeletal muscle, and retina from oxidative damage. Adequate Natural Tocopherols are required for normal development of the human neuromuscular system and maintenance of retinal function. Vitamin E is necessary in protecting mitochondria and axonal membranes of the nervous system from free radical damage.

Vitamin E = Natural Tocopherols?

The reason that they are called “All-natural Tocopherols” is related to the exploration of vitamin E. In 1922, Evans and Bishop of the College of California in the USA initially uncovered a fat-soluble compound in the study. The lack of this substance in male mice will lower fertility; if the absence of this substance in women computer mice, it will trigger the inability to conceive such as uterine atrophy. losing the unborn baby, so it was called “All-natural Tocopherols”.

Vitamin E is soluble in natural solvents such as fat and ethanol, insoluble in water, secure to warmth and acid, unstable to antacids, conscious oxygen, and also aloof to warm, but the activity of vitamin E is dramatically lowered throughout frying.

As a fat-soluble anti-oxidant and also free radical scavenger, vitamin E mostly battles against free radicals produced by lipid peroxidation on biological membrane layers and safeguards the structure as well as feature of organic membrane layers. Vitamin E is an important nutrient in the reproductive procedure and the most standard anti-oxidant in the reproductive system.

Vitamin E can be used in the adjuvant treatment of cardio and also cerebrovascular conditions, habitual abortion, the inability to conceive, and so on. It can additionally be utilized in the adjuvant therapy of anti-aging, exudative or inflammatory skin diseases, liver disease, liver cirrhosis, etc. It is extensively utilized in Clinical, pharmaceutical, food, feed, health care items as well as cosmetics sectors.

Lots of research studies have actually discovered that vitamin E supplements can boost the concentration, mobility and also portion of typical sperm in guys, therefore increasing the natural maternity price. As a result, the combined use of vitamin E in male infertility therapy can treat oligoasthenospermia, teratozoospermia, sperm DNA damage, etc.

About Products:
If you need Natural Tocopherols, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Natural Tocopherols manufacturer and supplier, ZSpharmac will provide Natural Tocopherols raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Natural Tocopherols Quotation