Naringin CAS 10236-47-2

Molecular Formula: C27H32O14

Formula Weight: 580.53

ZSpharmac: Naringin Supplier

Product Name: Naringin

CAS No: 10236-47-2

Purity: 99%

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Basic Info

Product Name:	Naringin
Other Names:	Naringina
CAS:	10236-47-2
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	Off-White Crystalline
EINECS No.:	233-566-4
Storage:	2-8°C
Provide:	Naringin MSDS； Naringin COA

What is Naringin?

Naringin is a flavonoid compound. Because there is no conjugation between ring An as well as ring B, there is a solid ultraviolet absorption peak at 282nm, which enables naringin to present numerous biological activities as well as medicinal results. Naringin can substantially improve neighborhood microcirculation and nutrient supply, Efficiently withstands dark circles and also exposes brilliant eyes. As well as studies have revealed that naringin has a repressive effect on the expansion as well as migration of melanocytes, so regarding deal with versus pigmented dark circles caused by coloring.

The extracted as well as detoxified naringin is a white to light yellow crystalline powder with an exceptionally bitter taste. After hydrolysis and also hydrogenation, naringin dihydrochalcone, which is 150 times sweeter than sucrose, is acquired. The solubility of naringin in normal temperature water is only 0.1%, and also the solubility can be increased to 10% at 75 ° C. It is quickly soluble in methanol, ethanol, acetone, hot acetic acid, dilute alkali remedy, and also formamide, and also insoluble in oil ether, benzene, as well as ether. as well as non-polar solvents such as chloroform.

Naringin Property

Melting point	166 °C
alpha	-91 º (c=1, C2H5OH)
Boiling point	559.35°C (rough estimate)
density	1.3285 (rough estimate)
vapor pressure	2.25Pa at 20℃
refractive index	-84 ° (C=2, EtOH)
storage temp.	2-8°C
form	crystalline
pka	7.17±0.40(Predicted)
color	off-white
optical activity	[α]20/D 80±10°, c = 1% in ethanol
Water Solubility	Soluble in water, alcohol, acetone and warm acetic acid.

The Efficacy and Role of Naringin

1. antibacterial, antiviral

Naringin and also hesperetin can prevent the development of Staphylococcus aureus, Escherichia coli, Shigella and typhoid bacillus in examination tubes, naringin can prevent yeast and also fungis, as well as stop virus-infected computer mice Safety results. Naringin and also hesperidin in grapefruit resemble various other flavonoids and also have anti-inflammatory properties.

2. lower blood sugar

In fresh grapefruit juice, it consists of insulin-like active ingredients, which can decrease blood sugar, and is a good food treatment for patients with diabetes and excessive weight.

3. Antispasmodic as well as enhances the result of vitamin C

The naringenin contained in grapefruit has noticeable antispasmodic effect. And also pomelo peel and hesperidin can improve the blood cell aggregation in the conjunctival vessels of the eyes and the reduction of capillary resistance in mice caused by lack of vitamin C.

4. expectorant and also antitussive

The external peel of pomelo is the typically made use of traditional Chinese medication orange red. The limonene and also pyrene consisted of in it can make the respiratory system secretions more and also thinner after inhalation, which is conducive to the discharge of sputum, as well as has an excellent expectorant and also antitussive effect.

Naringin can inhibit the damages of oxidative tension to the body’s interior organs, thus enhancing the body’s immunity and enhancing the body’s resistance to conditions. The antioxidant feature of naringin has a lot to do with its 2 active phenolic hydroxyl teams. Phenolic hydroxyl groups can increase the degrees of superoxide dismutase (TURF), glutathione peroxidase (GPx) and also catalase (CAT) by integrating with free radicals, energetic oxygen molecules and specific shift steel ions in the body. and also other tasks, play an antioxidant role.

Application of Naringin in Livestock and Poultry Production

Naringin has many advantageous biological functions mentioned over, and has the attributes of non-toxic (low poisoning), eco-friendly as well as environmental management, and also appropriates for application in animal husbandry as a feed additive or animal health and wellness medication. Today, the variety of studies on the application of naringin in animals and chicken production is reasonably little and also relatively single, and most research studies focus on the regulation of naringin on lipid metabolic rate, meat high quality and body resistance in livestock and also fowl.

Manage fat metabolic rate

In some monogastric animal experiments, naringin supplementation can considerably affect the fat metabolism of animals and also poultry, which appears as reducing lipid synthesis in animal blood, fat, liver and also other tissues, and also advertising fat decay.

1– Hager et al. fed Ross308 griddle hens from 11 days to 42 days with naringin-containing diet plans of 0.75 and also 1.5 g/kg completely dry issue (DM). The outcomes showed that compared to the control group, naringin The content of palmitic acid in the breast muscle mass of griddles in the glycoside team had a tendency to reduce, the material of polyunsaturated fatty acids (PUFA) often tended to enhance, and also the weight of abdominal fat decreased significantly. In addition, naringin likewise dramatically down-regulated the mRNA expression of fatty acid synthase (FASN) in griddle liver, but had no result on adiponectin, peroxisome proliferator-activated receptor γ (PPAR-γ) and FASN expression had no substantial effect.

2– Cho et al. used diets including 0, 30, 60, as well as 120 mg/kg DM naringin to feed rats for 6 weeks, and discovered that triglycerides in plasma and liver of the 3 naringin-treated teams (TG) and also cholesterol web content, as well as TG web content in parauterine fat decreased to differing degrees, but just the 120 mg/kg team reached a considerable degree. He believes that naringin can up-regulate peroxisome proliferator-activated receptor α (PPAR-α) and downstream target genes palmitoyltransferase 1 (CPT-1) and uncoupling protein 2 (UCP2) in rat liver expression, therefore decreasing the TG and also cholesterol levels in plasma and also liver.

3– Adil et al. additionally discovered that naringin can dramatically decrease the levels of TG and also cholesterol in rat plasma. Rotimi et al. provided naringin (50, 100, as well as 200 mg/kg body weight) to rats with kind diabetic issues for 21 successive days, and located that the materials of complimentary fats and TG in rat plasma reduced substantially, and also the rate of decline boosted with the quantity of naringin included. and the expression levels of lipase (LIPL) and also lecithin cholesterol acyltransferase (LCAT) in rat liver were impacted by naringin.

Biological Functions of Naringin

Boost meat quality

Including naringin to livestock and also chicken feed can enhance the antioxidant capability of meat, prolong the storage space duration of meat as well as enhance the color of meat, making animal meat more preferred with customers.

Boost the body’s immunity

Naringin can prevent the damage of oxidative tension to the body’s inner body organs, thereby enhancing the body’s resistance and improving the body’s resistance to conditions. The antioxidant feature of naringin has a lot to do with its 2 energetic phenolic hydroxyl groups. Phenolic hydroxyl groups can boost the levels of superoxide dismutase (TURF), glutathione peroxidase (GPx) as well as catalase (FELINE) by combining with free radicals, energetic oxygen molecules as well as specific shift metal ions in the body. as well as other tasks, play an antioxidant role.

Some researches in the last few years have actually revealed that naringin can enhance the immune feedback of livestock and also poultry under heat anxiety atmosphere and also reduce warmth tension feedback. Alhidary et al. provided 1 g as well as 2 g of naringin each week to 4-month-old Awasi lamb under heat problems (ordinary space temperature level: 38.3 ° C). After 60 days, the plasma healthy protein focus of the lamb in the 1 g treatment team approached that in the control group. Proportion of naringin enhanced dramatically, and also had better day-to-day gain (increase of 5.2%) and higher feed conversion efficiency (boost of 17.1%); 14 g, it was found that the total concentration of main antibodies in product of sheep was substantially boosted, the development rate was even more improved, and the activities of SOD as well as GPx in plasma also enhanced to varying degrees.

About That Product:
If you need Naringin, the cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Naringin manufacturer and supplier, ZSpharmac will provide Naringin raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.