1. Enhance infant’s intelligence and also memory
N-Acetylneuraminic Acid is a vital element of brain gangliosides. The material of sialic acid in the afferent neuron membrane is 20 times that of other cells. Because the transmission of mind details as well as the conduction of nerve impulses have to be recognized through synapses, as well as sialic acid is a mind nutrient that acts upon brain cell membranes as well as synapses, so sialic acid can promote The advancement of memory and also knowledge. Research studies have actually located that enhancing the content of sialic acid in the breastfeeding diet will raise the web content of sialic acid in the infant’s mind, and the expression level of genetics related to finding out will certainly additionally raise, therefore improving its learning as well as memory capabilities. In infants, the web content of sialic acid is only 25% of that in breast milk. Considering That N-Acetylneuraminic Acid is synthesized in the liver, in very early youth development, the brain creates quickly, while the liver develops extremely gradually. The sialic acid synthesized by the liver It is tough to meet the requirements of brain advancement, therefore, infants specifically require to supplement sialic acid. Infants fed by mommies who consumed bird’s nest throughout breastfeeding were smarter than other infants of the same age.
2. Anti-senile dementia
N-Acetylneuraminic Acid has safety as well as stabilizing impacts on afferent neuron. After the protease situated on the surface of afferent neuron membrane is combined with sialic acid, it can not be deteriorated by extracellular protease. In some neurological diseases, such as very early senile dementia and also schizophrenia, the web content of sialic acid in the blood or mind will reduce, and also after healing from drug therapy, the content of N-Acetylneuraminic Acid will certainly go back to typical, which reveals that sialic acid is associated with the growth of nerve cells. metabolic procedure.
Between molecules as well as cells, in between cells and also cells, and in between cells as well as the outside world, the N-Acetylneuraminic Acid at the end of the sugar chain can work as an acknowledgment site or mask the acknowledgment website. The sialic acid connected to the end of the glycosides through glycosidic bonds can efficiently avoid some important antigenic sites as well as recognition marks on the cell surface, thereby safeguarding these saccharides from being acknowledged as well as weakened by the surrounding body immune system.
4. Antibacterial, antiviral, antitumor
Due to the special framework of the 9-carbon amino sugar of the N-Acetylneuraminic Acid particle, there is no enzyme that deteriorates this material in the digestive tract system. Consequently, the polypeptide conjugate developed by it will certainly not be deteriorated by the enzymes in the digestive tract when it passes through the gastrointestinal system, and after that right into the intestine. In the digestive system, details sialic acid-polypeptide conjugates can develop competitive binding with pathogenic bacteria, toxic substances, and virions going into the digestive tract, therefore preventing digestive tract toxic substances, pathogenic germs, as well as virions from binding to intestinal tract mucosal cells. It can be seen that adding sialic acid to food can boost the anti-bacterial, detoxing and antiviral capacities of the intestine.
5. Hinder leukocyte attachment and anti-inflammation
When cells is inflamed or harmed, white blood cells collect around the swollen cells to apply anti-bacterial and anti-inflammatory results. In the 1990s, scientists in the United States discovered that the gathering of leukocytes is related to the process of cell attachment, as well as the process of cell adhesion is related to E-selection (E-Selection) of epidermal cells including sialyl tetrasaccharide nuclei externally of leukocytes. When swelling occurs, endothelial cells are stimulated by cytokines to generate E-selection, which can acknowledge tetrasaccharides externally of leukocytes and combine with them, making leukocytes abide by the vascular endothelium, and then reach the inflammatory tissue via the vascular endothelium. Therefore, synthesizing some sialic acid by-products with less complex frameworks and also even more effective than tetrasaccharides as sticky drugs to treat swelling will become a research hotspot.
6. Improve human immunity
N-Acetylneuraminic Acid will certainly not be weakened by digestive enzymes in the digestion system, and also can go into the intestinal system to stop pathogenic microbes from adsorbing on intestinal cells, and also contribute in withstanding numerous pathogenic bacteria. Free sialic acid in body fluids can protect against the adsorption of chilly viruses on the cell surface, as well as based upon this system, anti-cold drugs based upon sialic acid derivatives have actually been developed.
7. Boost intestinal tract absorption of nutrients
N-Acetylneuraminic Acid has a solid adverse charge as well as is usually located at the end of the glycoprotein or glycolipid externally of the cell membrane, which is the main resource of adverse charge on the cell membrane. The unfavorable charge of sialic acid makes red cell and also other cells drive away each other, staying clear of meaningless cell interactions in the blood flow. According to the concept that the contrary sex brings in each other, the favorably billed minerals as well as some vitamins (such as vitamin B12 consisted of in food and trace quantities) that go into the intestinal tract are quickly incorporated with sialic acid with a solid negative cost. As a result, sialic acid can improve the absorption capacity of the intestines for minerals and also vitamins, as well as supplementing sialic acid can enhance the body’s absorption of nutrients.
With the raising understanding and also expedition of the organic functions of N-Acetylneuraminic Acid, the exploration of biologically active substances led by sialic acid has come to be a new research study area. Sialic acid and its by-products are commonly utilized in food and health items. and medical applications are progressively extensive. It can be seen that sialic acid has a high health worth to the human body. In view of this, bird’s nest is considered as the front runner food for health care by increasingly more individuals.