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Musk Ketone CAS 81-14-1

Molecular Formula: C14H18N2O5

Formula Weight: 294.3

ZSpharmac: Musk Ketone Supplier 

Product Name: Musk Ketone
CAS No: 81-14-1
Purity: 99%

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Basic Info

Product Name:Musk Ketone
Other Names:Ketone Moschus
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Light Yellow Powder
EINECS No.:201-328-9
Provide:Musk Ketone MSDS;
Musk Ketone COA

What is Musk Ketone?

The history of muskone dates back to 1888, when German chemist Albert Baur stumbled upon it while trying to find a better way to create the eruptive TNT. In the fragrance market, muscone is known as a fixative since it can support volatility and also increase the persistence of perfume aroma.

Musk Ketone Property

Melting point 134-137 °C
Boiling point 436.08°C (rough estimate)
density 1.2051 (rough estimate)
vapor pressure 0.001Pa at 25℃
refractive index 1.5110 (estimate)
Fp 2 °C
storage temp. 2-8°C
solubility DMSO : 250 mg/mL (849.47 mM; Need ultrasonic)
Odorat 10.00 % in benzyl benzoate. fatty musk soapy dry floral powdery
Odor Typemusk
Water Solubility Insoluble (<0.1 g/100 mL at 20 ºC)


Musk Ketone Uses

  1. Musk Ketone is among the all-important finest nitro musks and also is an excellent fixative. It is commonly utilized in scent formulas, and can be used in those that need musk scent, specifically in wonderful, asian and hefty fragrance fragrances. When shown methyl ionone, cinnamon alcohol, benzyl salicylate, etc, it can create fine-grained scent. It can be used in soap significance in a proper quantity, as well as the dose is normally 1%-5%.
  2. Musk Ketone has an aroma comparable to natural musk. The fragrance is sensational and also sensible. Used as a fixative for cosmetic fragrances and also seasonal fragrances.

Production Method of Musk Ketone

From m-xylene by tert-butylation, acetylation along with nitration responses in the system. When isobutanol is used as the alkylating representative for tert-butylation, the reaction temperature degree is 50-54 ° C. It is almost useful to utilize isobutene for alkylation. In this situation, aluminum trichloride is utilized as a driver, and likewise the created 1,3-dimethyl-5-tert-butylbenzene is purified by vacuum cleaner purification (boiling point 85-90 ℃/ 0.0016-0.0019 MPa). Acetylation utilizes light weight aluminum trichloride as a chauffeur, and likewise the reaction temperature level is 58-60 ° C. Iron trichloride or zinc chloride can also be utilized, as well as the feedback temperature is 90-95 ° C. Throughout the nitration response, originally cool down the nitric acid to -8 -10 ° C, after that consist of 2,6-dimethyl-4-tert-butyl acetophenone, as well as respond at -5 -8 ° C. The nitrated item was cleaned with water, in addition to the resulting crude thing was recrystallized from ethanol.

About Products:
If you need Musk Ketone, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Musk Ketone manufacturer and supplier, ZSpharmac will provide Musk Ketone raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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