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Zhishang Chemical

Mogroside V CAS 88901-36-4

Molecular Formula: C60H102O29

Formula Weight: 1287.43

ZSpharmac: Mogroside V Supplier

Product Name: Mogroside V
CAS No: 88901-36-4
Purity: 99%

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Basic Info

Product Name:Mogroside V
Other Names:Momordica Grosvenori
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Solid
EINECS No.:695-005-3
Provide:Mogroside V MSDS;
Mogroside V COA

What is Mogroside V?

Luo Han Guo [Siraitiagrosvenorii (Swingle) C. Jeffery] is a creeping plant of Cucurbitacease (Cucurbitacease), primarily produced in Guilin, Guangxi, as well as also dispersed in Yunnan, Guizhou, Guangdong, Hunan as well as various other areas. Ripe Luo Han Guo fruit tastes really sweet as well as is generally rich in cucurbitane-type tetracyclic triterpene saponins, of which mogroside V (mogroside V) is the main pleasant part, with a dry weight material of as much as 1.6%. Today, Mogroside V removed from Luo Han Guo fruit has been extensively utilized in beverage and also artificial additive industries as a perfect low-calorie all-natural sweetener.

Mogroside V Property

Melting point 197~201℃
density 1.51
storage temp. 2-8°C
solubility Methanol (Slightly, Sonicated), Pyrindine (Slightly), Water (Slightly)
form Solid
color White to Off-White


Mogroside V Uses

  1. Mogroside V has the impact of decreasing blood sugar level and can be made use of as a supporting treatment for diabetes mellitus; it is rich in vitamin C and has anti-aging, anti-cancer as well as skin-beautifying effects; it has the result of decreasing blood fat and weight loss, and can assist in the treatment of hyperlipidemia and improve obesity picture of. It can be widely made use of in nutrition and also health items, infant food, blown food, flavoring, middle-aged and also senior food, strong beverage, bread, cold food, fast food, immediate food, and so on.
  2. Mogroside V has the results of clearing away warm and nourishing the lungs, smoothing the intestines and also laxative. Modern pharmacological research studies have shown that Luo Han Guo has the functions of alleviating coughing as well as eliminating phlegm, purging and also securing the liver, and also improving resistance. Mogroside is the primary energetic ingredient of Luo Han Guo, and the monomer task after separation and also filtration is more powerful than that of the total water decoction. The antispasmodic result of mogroside on separated tracheal as well as digestive tract convulsions might be among the product bases of the standard Chinese medicine Luo Han Guo in treating respiratory system and gastrointestinal diseases.

Mogroside V Control

Report one
A method for preparing mogroside V by molecular distillation, comprising the steps of:

1) After crushing the Luo Han Guo, pass through a 40-60 mesh sieve to obtain the Luo Han Guo powder. Weigh 60 g of Momordica grosvenori powder into a 1000 mL round bottom flask, add 500 mL of ethanol with a volume concentration of 80% to the round bottom flask, put the round bottom flask into an ultrasonic cleaner, and ultrasonically soak it under the condition of 200 KHz for 30 min;

2) After ultrasonic immersion, heat the round-bottomed flask with an electric heating mantle, and conduct reflux extraction for 5 h. After reflux extraction, suction filter and collect the filtrate. The filtrate is concentrated under reduced pressure to remove most of the solvent to obtain Luo Han Guo extract (this extract is a viscous fluid paste), and the yield of Luo Han Guo extract is 30.12%;

3) The Luo Han Guo extract was subjected to the first molecular distillation under the conditions of scraper rotation speed of 140 rad/min, distillation temperature of 40 °C, distillation pressure of 0.1 Pa, and feed rate of 0.3 mL/min to obtain the light The yield of fraction 1#, heavy fraction 2#, and Luo Han Guo heavy fraction 2# was 36.51%;

4) Heavy component 2# was subjected to the second molecular distillation under the conditions of scraper rotation speed of 70 rad/min, distillation temperature of 60°C, distillation pressure of 0.1 Pa, and feed rate of 0.5 mL/min to obtain mogroside-containing Light component 3# of V (the yield of light component 3# of Luo Han Guo extract is 3.63%),

Light fraction 3# containing mogroside V was freeze-dried for 24 h in a freeze dryer to obtain white powder crystals, which was the finished product of mogroside V.

Report two,
A method utilizing subcritical and molecular distillation to jointly prepare mogroside V, comprising the steps of:

1) Grind the Luo Han Guo with a mortar and pass through a 40-60 mesh screen to obtain the Luo Han Guo powder;

2) Take 200 g of Luo Han Guo powder and place it in a subcritical extraction kettle, add 1200 mL of n-butane and dimethyl ether with a volume ratio of 1:1 into the subcritical extraction kettle as the extraction agent, and extract at the extraction temperature of 10 °C and the extraction pressure Extract for 3 hours under the condition of 2.0 MPa to obtain Luo Han Guo extract;

3) The Luo Han Guo extract was concentrated under reduced pressure to remove 60% of the extractant, and then the distillation temperature was 50°C, the distillation pressure was 0.01 Pa, the scraper speed was 50 rad/min, and the feed rate was 0.1 mL/min. Mogroside V was obtained by molecular distillation at low temperature to obtain light components containing mogroside V, which were then freeze-dried for 24 h in a freeze dryer to obtain white powdery crystals, which was the finished product of mogroside V, with a yield of 13.65%.

The finished product of mogroside V prepared above was subjected to high performance liquid phase detection, and the detection results showed that the purity was 96.95%.

Determination Method of Mogroside V

To establish a RP-HPLC approach for the decision of the web content of Luo Han Guo saponin V in Luo Han Guo medical materials. Technique: Use lAiltma-C: (4.6 mmx250mm, 5um) chromatographic column, acetonitrile-water (23:77) as mobile stage, flow rate 1. omL · min-‘, detection wavelength 203nm, column temperature level 32 ℃. Outcomes: The straight variety of V of Luo Han Guo soap was 0.17 ~ 4.2 ug, and also the typical healing was 99.05% (RSD=0.78%, n=9). Verdict: The established technique has secure outcomes as well as excellent healing, which can be utilized to identify the web content of Luo Han Guo saponin V in Luo Han Guo.

About Products:
If you need Mogroside V, the cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Mogroside V manufacturer and supplier, ZSpharmac will provide Mogroside V raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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