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Methyl Sulfone CAS 67-71-0

Molecular Formula: C2H6O2S

Formula Weight: 94.13

ZSpharmac: Methyl Sulfone Cosmetic Raw Material Suppliers

Product Name: Methyl Sulfone
CAS No: 67-71-0
Purity: 99%

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Basic Info

Product Name:Methyl Sulfone
Other Names:Dimethyl Sulfone
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystals or Crystalline Powder
EINECS No.:200-665-9
Storage:Store Below +30°C.
Provide:Methyl Sulfone MSDS;
Methyl Sulfone COA

What is Methyl Sulfone?

Methyl Sulfone, also known as Dimethyl Sulfone (MSM), is an organic sulfur compound with a molecular formula of C2H6O2S and a molecular weight of 94.13 g/mol. It is a colorless, odorless, water-soluble solid that is highly bioavailable. Dimethylsulfone is used industrially and commercially as a solvent, food supplement, and ingredient in cosmetic and personal care products.

In the health and medical fields, dimethyl sulfone is well-known as a dietary supplement and is considered beneficial to maintaining joint health and can relieve joint pain and inflammation, although its specific mechanism and effect are still under scientific research. Additionally, it is used in skin care products because of its transdermal absorption capabilities and possible antioxidant properties, which are thought to help improve skin health and appearance.

Dimethyl sulfone also has applications in the chemical industry, such as as an intermediate in polymer manufacturing, a solvent, and a reagent in some chemical synthesis processes. Due to its relatively high safety profile, it is considered an ideal substance in a variety of applications.

Methyl Sulfone Property

Melting point 107-109 °C (lit.)
Boiling point 238 °C (lit.)
density 1,16 g/cm3
refractive index 1.4226
Fp 290 °F
storage temp. Store below +30°C.
solubility 150g/l
pka28(at 25℃)
form Crystals or Crystalline Powder
color White
Odorat 1.00?%. sulfurous burnt
Water Solubility 150 g/L (20 ºC)


Methyl Sulfone Uses

Joint Health: The most well-known application of dimethyl sulfone in the nutraceutical market is as a joint health supplement. It is widely believed to help reduce pain and inflammation and improve joint mobility in people with osteoarthritis. While its exact mechanism of action is still being studied, it is believed that it may support the repair of cartilage, ligaments, and muscles by increasing the availability of sulfur in tissues.

Antioxidant and Immune Support: Dimethylsulfone has also shown some antioxidant properties, fighting free radicals and reducing oxidative stress, which may benefit skin health and overall immune function.

Skin Care: In personal care products, dimethyl sulfone is used as an effective delivery vehicle due to its transdermal absorption capabilities, helping other active ingredients to better penetrate the skin. It is also thought to improve the skin’s ability to retain moisture, reduce dryness and roughness of the skin, and help treat acne, scars, and hyperpigmentation.

Hair care: In hair care products, dimethyl sulfone can strengthen hair, reduce breakage, and improve shine, in part because it helps repair damaged hair protein structure.

Polymers and Plastics: As a chemical intermediate, dimethyl sulfone can be used to synthesize certain types of polymers and plastics, improving their physical properties such as transparency, heat resistance, and toughness.

Solvents: Due to its solubility properties, dimethyl sulfone can be used as a solvent for certain chemical reactions, especially in those environments where non-polar and friendly to sensitive substances is required.

Agriculture: In agriculture, a small amount of research suggests that dimethyl sulfone may be used as a plant growth regulator to improve crop health and yield, although this application is not yet widespread.

Papermaking and textiles: In the papermaking and textile industries, dimethyl sulfone can be used as a processing aid to improve the color tone and physical properties of paper and fibers.

In some cases, dimethyl sulfone is also used as part of the mercury-containing sewage treatment agent to help remove harmful mercury ions through chemical reactions, reflecting its potential application value in environmental protection technology.

Prominent Applications of Methyl Sulfone in Makeup

Enhanced permeability: As an organic sulfur compound, Methyl Sulfone has good transdermal absorption ability due to its molecular structure characteristics. In cosmetic formulations, it can be used as a penetration enhancer to help other active ingredients penetrate the stratum corneum more effectively and reach the deeper layers of the skin, thereby enhancing the overall efficacy of the product, such as promoting the absorption of nutrients.

Antioxidant and anti-inflammatory effects: Although the direct antioxidant properties of Methyl Sulfone may not be as good as some classic antioxidants, it is speculated to indirectly participate in the antioxidant process by supporting the body’s own antioxidant system to fight free radical damage and reduce inflammation. reaction. This is helpful in slowing down the aging process of the skin and reducing damage to the skin from the external environment (such as inflammation caused by ultraviolet rays).

Skin health and repair: Sulfur (sulfur) is one of the important ingredients in skin, nails and hair. Methyl Sulfone can provide sulfur element to the skin, participate in skin metabolism, collagen synthesis and stratum corneum maintenance, helping to restore skin health. It has certain positive effects on improving skin texture and promoting wound healing.

Moisturizing and soothing: Although it is not a typical moisturizing ingredient, Methyl Sulfone indirectly helps the skin maintain moisture balance by improving the skin barrier function and reducing transepidermal water loss. It can provide certain soothing and moisturizing effects for sensitive or dry skin.

Formula compatibility: Due to its good chemical stability and relative mildness, Methyl Sulfone is easy to compound with other cosmetic raw materials and is suitable for use in many types of cosmetic formulas, including but not limited to facial creams, essences, anti-aging products, and after-sun repair. products etc.

Methyl Sulfone Features and Advantages

Good bioavailability: Methyl Sulfone has high bioavailability, which means it can effectively penetrate cell membranes, enter the blood circulation and be distributed to all parts of the body, which is essential for ingredients that need to function in the body.

Excellent solubility: It is soluble in both water and lipids. This characteristic allows Methyl Sulfone to be used in a wide range of formulation systems, whether it is water-based or oil-based cosmetics, pharmaceuticals or other chemicals. dispersion.

Antioxidant and anti-inflammatory potential: Although its direct antioxidant capacity is limited, Methyl Sulfone is believed to be able to indirectly exert antioxidant and anti-inflammatory effects by regulating redox balance and reducing inflammatory reactions, which is beneficial to skin health and anti-aging.

Improves nutrient absorption: As a penetration enhancer, Methyl Sulfone helps other active ingredients penetrate the skin or digestive tract wall, increasing their bioavailability and thus enhancing the effectiveness of the overall formula.

Participate in the biosynthetic process: Methyl Sulfone containing sulfur has the potential to promote the synthesis of biological macromolecules such as collagen and keratin in the skin, helping to maintain skin structure and elasticity.

Skin barrier improvement: It can help repair and strengthen the skin barrier, reduce water loss, improve dry and rough skin conditions, and is suitable for use in care products for sensitive and problematic skin.


Muizzuddin N, Benjamin R. Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing. Int J Vitam Nutr Res. 2022 Jul;92(3-4):182-191. doi: 10.1024/0300-9831/a000643. Epub 2020 Feb 21. PMID: 32083522.

As a company specializing in the production and supply of Methyl Sulfone raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the Methyl Sulfone raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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