Zhishang Chemical

Welcome to Zhishang Chemical      +86-176 5311 3209     Simon@sdzschem.com

Zhishang Chemical
Close this search box.

Methyl Sulfone CAS 67-71-0

Molecular Formula: C2H6O2S

Formula Weight: 94.13

ZSpharmac: Methyl Sulfone Cosmetic Raw Material Suppliers

Product Name: Methyl Sulfone
CAS No: 67-71-0
Purity: 99%

Navigation Bar

Basic Info

Product Name:Methyl Sulfone
Other Names:Dimethyl Sulfone
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystals or Crystalline Powder
EINECS No.:200-665-9
Storage:Store Below +30°C.
Provide:Methyl Sulfone MSDS;
Methyl Sulfone COA

What is Methyl Sulfone?

Dimethyl sulfone is a natural sulfide that boosts the capacity of the body to produce insulin as well as also promotes the metabolic rate of carbohydrates. It is a critical substance for the synthesis of collagen in the body. It can market injury healing, and also can also add in the synthesis along with activation of vitamin B, vitamin C, in addition to biotin needed for metabolic price as well as nerve wellness as well as health. It is called “all-natural enhancing carbon compound”. Contained in the skin, hair, nails, bones, muscles as well as additionally numerous body organs of the body, it mainly exists in the ocean and additionally dirt in nature, in addition to is soaked up as a nutrient throughout plant growth. Humans can get it from veggies, fruits, fish, meat, Intake from foods such as eggs as well as additionally milk. When doing not have, it will certainly set off wellness and also wellness issues or conditions. It is the major substance for the human body to keep the equilibrium of organic sulfur parts. It has restorative worth as well as healthcare features for human disease, as well as also is a vital medicine for human survival in addition to wellness and wellness protection., it is frequently made use of abroad as a dietary item as crucial as vitamins. my nation’s application study on dimethyl sulfone has not yet been well created, so currently all items are exported.

Methyl Sulfone Property

Melting point 107-109 °C (lit.)
Boiling point 238 °C (lit.)
density 1,16 g/cm3
refractive index 1.4226
Fp 290 °F
storage temp. Store below +30°C.
solubility 150g/l
pka28(at 25℃)
form Crystals or Crystalline Powder
color White
Odorat 1.00?%. sulfurous burnt
Water Solubility 150 g/L (20 ºC)


Applications of Methyl Sulfone

Sulfur is one of the most abundant element in the human body after carbon, oxygen, nitrogen, and hydrogen. Sulfur shortage will generate matching diseases Consequently, as early as 1985, someone proposed a license for the application of Methyl Sulfone in food and medication. Later, study on dimethyl sulfone in food and medicine was together reported. Research shows that dimethyl sulfone, as a dietary nutritional supplement, has a good supporting effect on lots of diseases. Human food originally contains significant quantities of dimethyl sulfone. Nevertheless, dimethyl sulfone will certainly be lost during transport as well as storage space of several foods (veggies, fruits, meat, eggs, milk, fish and shellfish, and so on).

A lot more significantly, individuals do thermal processing (steaming, boiling, frying, frying, stir-frying, roasting, etc) when eating, causing a big loss of Methyl Sulfone. Therefore, many people are incapable to acquire the metabolically required quantities of DMSO from their diet, creating certain health problems. The United States, Canada and other countries have actually provided nutritional supplements based upon dimethyl sulfone to supplement the deficiency of dimethyl sulfone in the diet plan. Research study shows that as a supplement, DMSO has far better results on the adhering to wellness concerns.

Routine supplementation of Methyl Sulfone in the diet plan has a good result on the avoidance as well as treatment of stomach diseases.

1) Many individuals have no intestinal abnormalities in the place where they live, but when taking a trip to various other places, they will certainly suffer from “acclimatized” looseness of the bowels, which is in some cases challenging to deal with despite having antibiotics. Research studies have actually revealed that 40 mg/ml dimethyl sulfone can quickly kill microorganisms. Usage 300 mg of dimethyl sulfone on a daily basis to deal with unclean water in travel locations to stop “adapted” looseness of the bowels.

2) People with hyperacidity generally take metal hydroxide or histamine 1-1-2 antibodies. Nevertheless, after long-lasting usage, its result slowly lowers or perhaps becomes inefficient. Supplementing 500mg of dimethyl sulfone with your diet plan every morning as well as evening can improve the efficacy.

3) Looseness of the bowels and also constipation are two opposite symptoms. If you take 500 ~ 750mg of dimethyl sulfone in your day-to-day diet plan, as well as if essential, take 1000mg of vitamin C at the same time, irregular bowel movements or diarrhea can be addressed.

4) The collaborating formula of Methyl Sulfone and dimethyl sulfoxide or dimethyl sulfone, dimethyl sulfoxide and also oxidized purinol (or allopurinol) has a very apparent effect on the prevention and therapy of gastrointestinal cancer cells.

This license utilizes mice for experiments, infusing 10 mg/Kg of the health hazard dimethylhydrazine. The blank team consumes a regular diet regimen, as well as the examination team beverages 10% dimethyl sulfone and also 10% dimethyl sulfoxide day-to-day or beverages 10% dimethyl sulfone and also 10% purinol (or allopurinol). After 28 weeks, all the empty groups were cancer causing, while no cancer was discovered in the test group, verifying that it has a solid capacity to prevent carcinogenesis. People with gastrointestinal cancer were provided 5 ml of 10% dimethyl sulfone as well as 10% dimethyl sulfoxide solution 4 times a day on the 5th day after surgical treatment. After two years, 46% more people in the therapy group survived than the control team.

The survivors remained to take the above option by mouth. After 4 years, 20% of the people in the treatment team were still alive, while less than 3% of the people in the control team were alive. Scientists think that the intestinal system of people with gastric cancer is attacked by oxygen totally free radicals created by metabolic process, bring about cell loss and damage and the spread of cancer cells. Dimethyl sulfone and dimethyl sulfoxide improve each other and get rid of oxygen cost-free radicals produced by stomach cancer, therefore improving survival rate.

Rheumatoid Arthritis, Rheumatoid Arthritis, and so on bring inconvenience and also pain to patients (particularly in the early morning or when the weather condition adjustments). For a very long time, people have actually used aspirin, non-steroidal analgesics, and so on to aid patients soothe pain. These medications are made use of for a very long time, and also some impacts progressively lower, and also some produce negative effects such as bloating and belly pain. In the study of joint inflammation individuals, it was located that the sulfur web content of cartilage in people is just 1/3 of the sulfur web content in typical cartilage material. Supplementing cystine can minimi

ze the joint fluid to be thicker as well as extra viscous, thus reinforcing the protective feature of the periosteum, minimizing the rubbing of bones and joints, and also lowering discomfort.

A compound composed of Methyl Sulfone, Glucosamine Sulfate, and Active Dried Bone Powder, which has a significant impact on rheumatoid arthritis. Generally, a capsule including 800 mg of dimethyl sulfone, 1200 mg of glucosamine sulfate, and also 1200 mg of active dry combined bone powder is taken daily. The discomfort is alleviated after 7 days, and also the discomfort disappears after 2 weeks, and the initial adaptability is recovered. Arthritis patients commonly experience stomach bloating and headaches when taking painkillers, however this side effect can be gotten rid of by adding dimethyl sulfone to the diet. Dietary supplements made up of dimethyl sulfone, glucosamine sulfate and also chondroitin sulfate already exist out there of the United States, Canada and also other nations.

Although its function is not indicated, basic details states that chondroitin belongs of cartilage. The combination of these three parts need to have synergistic impacts, and also each part can be utilized as a supporting food for arthritis treatment. Therefore, the three elements are effective medication as well as organic food for dealing with arthritis.

Some people have noticeable allergies to foreign objects, such as many plant pollen, plastic products, etc, and develop regular allergies: rash, watery eyes, drippy nose as well as mucous, eye as well as nose inflammation, sneezing, hoarseness as well as itchiness, etc. Individuals take antiallergic drugs, the majority of can deviate for the better. However the result gradually deteriorates or has side effects. And also some people take antiallergic medications without obvious result. For instance, when taking anti-allergic medicines, add 250 to 1000 mg of dimethyl sulfone to their diet each day. After a week, severe allergic signs will certainly be dramatically reduced. The anti-allergic drugs can be progressively reduced, and also the allergy can even be controlled.

Some people experience gastric “hay fever” allergic reactions. Although they utilize anti-allergic medicines and also anti-allergy sprays to manage their symptoms, their effects slowly damage with long-term usage. For instance, supplementing 500mg of dimethyl sulfone in the everyday diet can gradually minimize the frequency of spraying anti-allergic medicines, as well as even make the symptoms go away. Lots of people have allergic reactions to fish and shellfish (fish, shrimp, kelp, shellfish, etc) and also medicines (penicillin, aspirin, and so on), and also a couple of people have specific degrees of allergies to particular foods (such as cereals, milk, etc) response. Researches have revealed that by adding 100-1000 mg of dimethyl sulfone to the everyday diet regimen according to the level of allergic reaction, the allergic reaction can be gotten rid of or lowered.

Methyl Sulfone is the source of glutathione antioxidant sulfur, so it plays an extremely vital role in getting rid of oxygen totally free radicals created by the human body, consequently enhancing the body’s immune guideline. Research studies have actually revealed that either dimethyl sulfone or vitamin C alone is much less immunomodulatory than the combination of both. If the substance of dimethyl sulfone as well as vitamin C contains a percentage of β-1,3- glucan, its laid over immunomodulatory feature will certainly be much better. The very best composition supplied by the patent is: dimethyl sulfone 1500mg, vitamin C 2000mg, β-1,3- glucan 2-3 mg.

Methyl Sulfone is used to prepare housewives’ skin protection lotion, skin cream, exterior ointment for the therapy of dermatitis, skin cancer cells, and so on. It is made from 5g of dimethyl sulfone, 4g of (deposited) sulfur, 2g of salicylic acid, 1g of menthol, as well as cetyl alcohol included in 100g to make a paste for housewives to shield as well as boost their skin. In order to maintain the skin moist and also not fractured, you can utilize 5g of dimethyl sulfone, 2 g of cysteine hydrochloride, 1g of taken shape menthol, and include 100g of cetyl glycol to make a skin moisturizing ointment. For dermatitis, skin cancer, as well as mucocutaneous cancer cells, 5g of dimethyl sulfone, 1g of oxidized purinol (or allopurinol), 1g of menthol, 100,000 devices of vitamin A, as well as 1g of vitamin E can be mixed with cetyl alcohol to 100g. into a restorative lotion.

According to the data, Methyl Sulfone has other features in medication. In some people with emphysema, it might be caused by smoking cigarettes, which impairs lung feature and pleural circulation. Provide 500 mg of dimethyl sulfone daily for six to eight weeks till oxygen supply reaches the typical array. The dimethyl

sulfone level in his blood additionally rose to above 5mg/Kg. Some clients with emphysema that have difficulty walking were given 1,000 mg of dimethyl sulfone and vitamin C daily, as well as their walking range a minimum of tripled after two to four weeks.

Some patients have extreme snoring throughout sleep. The license [19] proposes to impart 10 ~ 16% dimethyl sulfone liquid solution right into the person’s nose to quit snoring. Mosquito bites are exceptionally typical in summer. If you have sufficient Methyl Sulfone in your everyday diet plan to make sure that the dimethyl sulfone web content in your blood exceeds 1ppm, it can minimize the itching and also discomfort at the bite site. Some people who are prone to sweating to draw in insects can take suitable vitamin B supplements along with dimethyl sulfone. The diastolic blood pressure was above 90mmHg, which could not be lowered also after managing food and also using drugs. After supplementing 500mg of dimethyl sulfone in the everyday diet, after four to 6 weeks, the systolic and also diastolic blood pressures were both at typical values.

Hair, nails, skin, and so on in the body are all high-sulfur-containing tissues. For hair loss, you can use 5g dimethyl sulfone, 2 g dimethyl sulfoxide, 2 g cysteine hydrochloride, 2 g methylmethionine sulfonate chloride, 1 g taken shape menthol, and include castor oil to 100 g. Use the ready medicine on the scalp where the continuing to be hair is shed, as well as massage therapy for a couple of mins each time for a number of days. At the same time, covering the agent overnight can enable the hair to be fixed once more. It can be discovered from the Internet that dimethyl sulfone is beneficial to wellness in several aspects: asthma, tendinitis, muscle spasms, pain in the back, increased physical stamina, reducing muscle mass discomfort after training, cleansing in the body, promoting blood circulation, accelerating wound healing, and also Aids restore appeal to skin and also nails. As well as applications for sun burns, scalds, cuts and also abrasions, antibacterial, and so on.

Preparation of Methyl Sulfone

1. Oxidation under UV irradiation

The oxygen is irradiated by ultraviolet rays and also entered the dimethyl sulfoxide remedy. The oxidation reaction is carried out under ultraviolet irradiation. The produced dimethyl sulfone is frozen with ice seawater to precipitate the crystals. splitting up. It can be recrystallized if necessary. This oxidation process is also the procedure of generating dimethyl sulfoxide and also dimethyl sulfone from dimethyl sulfide in nature.

2. Oxidation of nitrogen oxide

Dimethyl sulfoxide is put into the reaction kettle, heated to 140 ~ 146 ° C, and also nitrogen dioxide is gone through for oxidation The response waste gas is oxidized with oxygen to nitrogen dioxide and afterwards returned to the response. After the reaction, it was cooled with icy brine to crystallize dimethyl sulfone, and also filteringed system to obtain the unrefined item of white needle crystals. The distillate accumulated at 138 ~ 145 ° C (740mmHg) by distillation is the completed product.

3. Hydrogen peroxide oxidation.

Include dimethyl sulfoxide into the reaction pot, warmth to 90 ~ 100 ° C, include 27.5% hydrogen peroxide dropwise, reflux the response, coating including the hydrogen peroxide dropwise, and also continue the reaction for a number of hours. Filter, cool with ice-salt water to speed up dimethyl sulfone crystals, centrifuge, wash the crystals with 95% ethanol or recrystallize to get the fine item. drying. The mommy liquor is focused as well as taken shape for recovery. The overall yield is 90%~ 92%.

Methyl Sulfone Bioavailability

Biochemically, no structural or security distinctions were located in between synthetic MSM and also naturally occurring MSM. Because the concentration of MSM from food sources is only 0.01 ppm, synthetically generated MSM enables customers to take reduced dosages to service the body without ingesting huge quantities of food.

Exogenous MSM enters the body in the form of nutritional supplements as well as foods such as fruits, vegetables, grains, beer, wine, coffee, tea, and milk. In addition to exogenously supplemented MSM, in vivo microbial activity on methionine, methyl mercaptan, DMS, and DMSO in vivo also advertises the enrichment of MSM in animal hosts. Diet-induced modifications in the gut microbiota can impact serum MSM focus in rats as well as expectant plants. That is to claim, the intestinal tract flora prone to diet regimen, workout or other factors will certainly influence the body’s application of MSM.

Pharmacokinetic research studies have actually shown that Methyl Sulfone can be swiftly absorbed in rats and humans, and also the absorption time is within 2.1 h as well as 1h specifically. There are comparable experiments to study the usage of DMSO in apes. Within 1-2 hours after intragastric management, it was discovered that DMSO can be rapidly converted into MSM. When the body consumes DMSO, regarding 15% of the liver microsomes are oxidized to MSM with the engagement of NADPH2 and O2.

In a lately released human research, 20 healthy men consumed 3 grams of MSM each day for 4 weeks. After all male subjects consumed MSM, serum MSM levels increased, as well as the majority of male topics had higher lotion Methyl Sulfone degrees in the fourth week and also better increased in the 2nd week. These outcomes recommend that oral MSM can be soaked up by healthy and balanced grownups and gradually build up in the body with long-term intake.

About Products:
If you need Methyl Sulfone as a cosmetic raw material, please contact our service staff directly and we will provide you with high-quality products at the best price.
As an experienced Methyl Sulfone manufacturer and supplier, ZSpharmac will provide Methyl Sulfone raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Methyl Sulfone Quotation