Zhishang Chemical

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Zhishang Chemical

Methyl Salicylate CAS 119-36-8

Molecular Formula: C8H8O3

Formula Weight: 152.15

ZSpharmac: Methyl Salicylate Supplement

Product Name: Methyl Salicylate
CAS No: 119-36-8
Purity: 99%

Basic Info

Product Name:Methyl Salicylate
Other Names:Ammonium Mercaptoacetate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Flavors and Fragrances
Appearance:Clear Colorless to Pale Yellow Liquid
EINECS No.:204-317-7
Storage:Inert Atmosphere,Room Temperature
Provide:Methyl Salicylate MSDS;
Methyl Salicylate COA

What is Methyl Salicylate?

Methyl salicylate strong aroma of wintergreen oil. The relative molecular mass is 152.16. Family member thickness 1.1738. Melting point -8.6 ℃. Boiling point 223.3 ℃. Flash point 96 ℃. Refractive index 1.5360. Insoluble in water, soluble alike natural solvents such as ethanol, ether and antarctic acetic acid. It is easy to alter shade when exposed to the air. Rat dental LD50887mg/kg.

It is gotten by distillation of the leaves of the heather plant holly. its most common usage is for seasoning tooth paste. IFRA has no limitations. Methyl salicylate is acknowledged by FEMA as GRAS, FEMA number 2745, and the European Council checklists methyl salicylate in the list of artificial flavorings that can be utilized in food without damaging human wellness, and also its optimum dosage is 8400mg/kg, The ADI worth was 0.5 mg/kg.

Methyl salicylate can be utilized in the formula of edible flavors. It is momentarily allowed to be used in my country’s GB2760-1996 guidelines. The ADI worth is 0 to 0.5. It is often made use of in the prep work of strawberry, vanilla, grape and also various other fruit tastes for food and In beer, it can additionally be utilized to taste fructose, soft drinks, and so on. Furthermore, methyl salicylate is likewise used in industrial areas such as chemicals, pesticides, polishing agents, inks, paints, polyester fiber coloring providers, etc.

Methyl Salicylate Properties:

Melting point -8–7 °C (lit.)
Boiling point 222 °C (lit.)
density 1.174 g/mL at 25 °C (lit.)
vapor density 5.26 (vs air)
vapor pressure 1 mm Hg ( 54 °C)
refractive index n20/D 1.536(lit.)
Fp 226 °F
storage temp. Inert atmosphere,Room Temperature
solubility Very slightly soluble in water, miscible with ethanol (96 per cent) and with fatty and essential oils.
pkapKa 9.90 (Uncertain)
form Liquid
color Clear colorless to pale yellow
Water Solubility 0.07 g/100 mL (20 ºC)


Methyl Salicylate Uses

  1. Methyl salicylate is used as a scent for food, tooth paste, cosmetics, as well as also for painkillers, pesticides, gloss, inks, and so on.
  2. Methyl salicylate can be utilized as a modifier in some flower fragrances, such as ylang ylang, magnolia, acacia, mimosa, tuberose, gardenia, citronella, etc. Generally made use of in pharmaceutical products as well as hygiene products such as toothpaste, tooth powder, mouthwash, talcum powder, wind-dispelling oil, etc. It can also be used to add scent to industrial products such as adhesive, adhesive paper, card stickers, paste, etc. It can likewise be used in edible tastes, such as strawberry, grape, walnut, spearmint, and seasoning taste as special eco-friendly gas.
  3. Methyl salicylate is utilized in the printing and also coloring market as a high temperature warmth carrier.
  4. Methyl salicylate is suggested as a temporarily allowed food flavoring. Mostly used to prepare beer, periodontal and also fruit tastes as well as synthetic cinnamon oil.
  5. Methyl salicylate has a limited and also strong odor comparable to stagwort. When used as a flavor, it is typically utilized as a flavoring representative for cavity medications and paints in pharmaceutical prep work. It is additionally made use of generally tastes, such as qianshu as well as various other spices. Various other oral medicines such as chewing periodontal and mouthwash are likewise used. Methyl salicylate is likewise used as a solvent as well as intermediate for the manufacture of chemicals, fungicides, scents, coatings, aesthetic inks and also fiber dyeing auxiliaries. Methyl salicylate reacts with ammonia to develop salicylamide, which is made use of for the production of ethylsalicylicamide, an antipyretic analgesic, which itself is additionally an antipyretic and also analgesic. Methyl salicylate can be acquired by acetylation of methyl salicylate (C10H10O4, [580-02-9]. Place methyl salicylate as well as acetic anhydride right into the reaction pot, add sulfuric acid under stirring, the response temperature does not surpass 60 ° C, about 1 h, after the reaction is finished, pour the catalyst right into ice water to precipitate crystals, filter, clean, as well as completely dry to get the name. Methyl acetylsalicylate. 4-Hydroxycoumarin can be gotten by cyclization of acetylsalicylic acid. Methyl salicylate is made use of as a topical inflammation agent as a medication.
  6. Methyl salicylate is used in perfumery formulas as well as additionally as a solvent, preservative and disinfectant.
  7. Methyl salicylate has anti-inflammatory and analgesic impacts as well as is extensively made use of in joint and muscular tissue pain relief creams, casts as well as oils. It is also utilized as a solvent as well as various intermediates for the manufacture of pesticides, fungicides, polishing agents, anti-copper representatives, fragrances, food, cosmetics, toothpaste, layers, inks as well as fiber dyeing accessories.
  8. Methyl salicylate is utilized in solvents, stimulants. Topically made use of for joint or muscle pain. UV absorber in fragrances as well as sunscreen lotions.

Production Method of Methyl Salicylate

Methyl salicylate exists widely in nature and is the main component of stagwort grass and Xiaodang medicated oil. It also exists in the essential oils of tuberose, sorghum, ylang-ylang, cloves, tea, etc. Industrially, it is obtained by esterification of salicylic acid and methanol in the presence of sulfuric acid. Dissolve salicylic acid in methanol, add sulfuric acid, stir and heat, react at 90-100 °C for 3 hours, cool down to below 30 °C, separate the oil layer, wash with sodium carbonate solution to pH 8 or more, and then wash with water once. Under reduced pressure distillation, collect 95-110 ℃ (1.33-2.0kPa) fraction, namely obtain methyl salicylate. The yield is above 80%. The content of general industrial methyl salicylate can reach 99.5%. Raw material consumption quota: salicylic acid 950kg/t, methanol 400kg/t.

Methyl Salicylate Environmental Fate/Exposure Summary

Methyl salicylate is generated in big quantities and also might be released right into the environment during its production, transport, disposal and also use in perfumes as well as sunburn creams, in addition to in food, beverages and pharmaceuticals. It is additionally an unpredictable plant as well as is launched by some plants. In soil, methyl salicylate might biodegrade. In alkaline dirts, chemical hydrolysis may trigger its loss. It may additionally go through straight photolysis on the soil surface area. Methyl salicylate is anticipated to be fairly mobile in soil. It needs to be partially volatilized from dry dirt. If released into water, methyl salicylate should slowly volatilize (49 days half-life in the model river), biodegrade, and also vanish as a result of route photolysis as well as photooxidation in surface waters. In alkaline water, hydrolysis might also be an important fate process (estimated half-life of 2 week at pH 7.5). Methyl salicylate is not likely to bioconcentrate in aquatic microorganisms. Methyl salicylate will respond with photochemically produced hydroxyl radicals in the environment with an estimated half-life of 1.4 days. It is relatively soluble in water as well as might be washed away by rainfall. Courses of exposure to methyl salicylate are consumption of food and skin contact with different customer products. Job-related exposure may be via skin call and also inhalation.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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