Zhishang Chemical

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Zhishang Chemical

Methyl Phenylacetate CAS 101-41-7

Molecular Formula: C9H10O2

Formula Weight: 150.17

ZSpharmac: Methyl Phenylacetate Supplier

Product Name: Methyl Phenylacetate
CAS No: 101-41-7
Purity: 99%

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Basic Info

Product Name:Methyl Phenylacetate
Other Names:Phenylacetic Acid methyl Ester
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colourless Neat
EINECS No.:202-940-9
Storage:Store Below +30°C.
Provide:Methyl Phenylacetate MSDS;
Methyl Phenylacetate COA

What is Methyl Phenylacetate?

Methyl phenylacetate is an organic compound, the corresponding methyl ester of phenylacetic acid, with the chemical formula C6H5CH2COOCH3.
Methyl phenylacetate exists in brandy, chili, black pepper, coffee, honey and some wines, and has a strong smell similar to honey. Methyl phenylacetate is sometimes used in fragrance and perfume manufacture as a source of honey aroma.
Methyl phenylacetate can generate methyl diazophenylacetate with p-acetamidobenzenesulfonyl azide under alkaline conditions.

Methyl Phenylacetate Property

Melting point 

107-115 °C

Boiling point 

218 °C (lit.)


1.066 g/mL at 20 °C (lit.)

vapor pressure 

16.9-75Pa at 20℃

refractive index 

n20/D 1.503(lit.)


195 °F

storage temp. 

Store below +30°C.


Chloroform (Slightly), Methanol (Slightly)





Water Solubility 

Miscible with water.



Methyl Phenylacetate Uses

  1. Methyl phenylacetate is utilized as a taste for the preparation of tastes such as honey, scrumptious chocolate, and cigarette.
  2. Methyl phenylacetate has a honey-like pleasant taste as well as also a somewhat musky fragrance. It is generally made use of to prepare flower scents, such as rose and also briar scents, cigarette as well as also soap. The item is also used in organic synthesis in addition to the manufacture of medicines atropine and likewise anisodamine (synthetic strategy).

Methyl Phenylacetate Production Method

From phenylacetonitrile derived by hydrolysis and esterification. Put methanol right into a completely dry glass-lined reaction pot, mix and also cool down to below 30 ° C, include sulfuric acid dropwise, after the addition, raise the temperature to 90 ° C, begin to include phenylacetonitrile dropwise, regulate the temperature at concerning 95 ° C, and also surface including 1.5 h. After reacting at 95-100 ° C for 6 hrs, cool to below 40 ° C, include water comparable to around 0.6 times of the reaction service to water down. Stand to different acid water, include saturated sodium carbonate service for neutralization and also cleaning, as well as throw out the water layer. Dehydration with anhydrous calcium chloride, fractional distillation under lowered pressure to get methyl phenylacetate with a yield of 80%. One more preparation approach is to pass benzyl chloride, anhydrous methanol as well as water to hydrogen chloride to saturation under reflux, place for 2-3h, and also heat for 1h to produce the product.

Ecological Information on Methyl Phenylacetate

The production and also use of methyl phenylacetate as a synthetic food flavoring agent may lead to its launch to the environment with numerous waste streams. It is made use of in the manufacture of artificial fragrances and might be launched straight into the setting. Methyl phenylacetate is a constituent of different plants and additionally some mycobacteria. If released to air, a vapor stress of 0.13 mmHg at 20 ° C shows that methyl phenylacetate will certainly simply exist as a vapor in the ambience. Gas-phase methyl phenylacetate will certainly wear away free of charge radicals in the atmosphere by reacting with photochemically generated hydroxyl groups; the half-life of this feedback in air is approximated to be 8.6 days. Methyl phenylacetate does not take in UV light at wavelengths > 290 nm and likewise is consequently not anticipated to be susceptible to photolysis by straight sunlight. If released to dirt, methyl phenylacetate is expected to be very mobile based upon an approximated Koc of 74. Based upon an estimated Henry’s regulation constant of 1.4X10-5 atm-cu m/mole, volatilization from wet soil area could be an essential fate treatment. Methyl phenylacetate has a vapor pressure of 0.13 mmHg as well as also remains in liquid kind at ambient issues present; consequently, methyl phenylacetate may volatilize from dry dirts. Utilizing the shut container examination, 75% destruction was accomplished within 28 days, suggesting that biodegradation is a vital environmental destiny treatment in dust as well as also water. If launched into water, methyl phenylacetate is not expected to adsorb to put on hold solids as well as additionally sediment based upon the approximated Koc fads. Volatilization of the area from water may be an essential destiny procedure, based upon the approximated Henry’s guideline constant for this compound. The approximated volatilization half-lives were 2 days as well as 28 days for the version river along with layout lake, especially. An estimated BCF of 7.5 recommends a low bioconcentration capacity in water microorganisms. Methyl phenylacetate could go through slow hydrolysis in alkaline dirt as well as water. Job straight exposure to methyl phenylacetate may accompany breathing as well as dermal direct exposure to this substance in workplaces where methyl phenylacetate is produced or taken advantage of. Limited protection in addition to use details suggest that the basic population might be exposed to methyl phenylacetate with consumption, cigarette smoking, breathing, and face contact with customer products including methyl phenylacetate.

About Products:
If you need Methyl Phenylacetate as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Methyl Phenylacetate manufacturer and supplier, ZSpharmac will provide Methyl Phenylacetate raw materials for customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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