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Mercaptoacetic Acid CAS 68-11-1

Molecular Formula: C2H4O2S

Formula Weight: 92.12

ZSpharmac: Mercaptoacetic Acid Cosmetic Raw Material Suppliers

Product Name: Mercaptoacetic Acid
CAS No: 68-11-1
Purity: 99%

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Basic Info

Product Name:Mercaptoacetic Acid
Other Names:Thioglycolic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Liquid
EINECS No.:200-677-4
Storage:Store at +2°C to +8°C.
Provide:Mercaptoacetic Acid MSDS;
Mercaptoacetic Acid COA

What is Mercaptoacetic Acid?

Pure thioglycolic acid is a colorless and also transparent fluid, while commercial products are colorless to slightly yellow and have a solid pungent odor. Miscible with water, ethanol and ether. Perming items make use of thioglycolic acid to damage some of the disulfide bonds in the hair to change the curvature of the hair to attain perming as well as hair designing results. Nevertheless, thioglycolic acid is harmful as well as is easily absorbed via the skin and respiratory system system, creating symptoms such as skin damages and also allergies, and also affecting body metabolism. Long-term exposure can cause damages to various cells as well as organs, and has strong mutagenicity and reproductive poisoning. For that reason, it requires to be strictly controlled.

Mercaptoacetic Acid Property

Melting point 28 °C (lit.)
Boiling point 217 °C/150 mmHg (lit.)
density 1.097 g/mL at 25 °C (lit.)
vapor density 3.6 (vs air)
vapor pressure <0.98 atm ( 100 °C)
refractive index n20/D 1.477(lit.)
Fp 280 °F
storage temp. 2-8°C
solubility H2O: 1 M at 20 °C, clear, colorless
form Viscous Liquid or Low Melting Solid
color APHA: ≤15
Specific Gravity1.09
OdorMild ammoniacal; faint, fishy; characteristic.
PH11.0-12.0 (25℃, 1M in H2O)
pka8.88(at 25℃)
explosive limit2.1-10.6%(V)
Water Solubility MISCIBLE


Mercaptoacetic Acid Uses

1. As a deterioration inhibitor for oil drilling liquids, a brine of zinc bromide and also calcium bromide is usually used in high-pressure oil and also gas well drilling. Its density is 2301kg/m2. When the development temperature level is high, it will seriously rust devices and also drill bits. Ammonium thioglycolate is currently used as a rust inhibitor abroad. When the temperature is as high as 204 ° C, the deterioration rate is 80mpy, while it is 202mpy without adding the deterioration inhibitor.

2. Copper web content minimizing representative in molybdenum ore flotation protection. Currently, sodium cyanide is made use of to reduce the web content of chalcopyrite in residential flotation. Cyanide is very poisonous, triggers severe environmental pollution, and also its efficiency is not lasting. Nowadays, thioglycolic acid has actually been commonly made use of abroad as a decreasing representative for hole content. The impact is great and the environmental pollution is mild.

3. Corrosion eliminator: Thioglycolate has long been made use of abroad as a rust eliminator as well as range eliminator for iron and also iron-based alloys, copper as well as copper-based alloys. The effect is great and also can be made use of in water-cooling systems such as a/c unit as well as internal burning engines. For corrosion triggered by high-temperature and also high-pressure central heating boilers running under supercritical stress, utilizing Mercaptoacetic Acid not only has exceptional results, yet likewise substantially improves environmental pollution.

4. The tarnish eliminator of natural leather sun tanning remedy uses chrome tanning liquid to tan the leather, which frequently leaves stains on the leather. Specifically the stains obtained by using salt dichromate to oxidize organic substances such as β-methylnaphthalene in sulfuric acid tool. Trivalent chromium fundamental chromium sulfate service is utilized to tan natural leather, as well as the spots are extremely noticeable.

5. Home drain flow representatives. Standard drain flow representatives are made of sulfuric acid, salt hydroxide or strong antacids and also solid oxidants, which can conveniently trigger burns, poisoning and also deterioration when utilized. A brand-new kind of sewage system dredging agent with exceptionally reduced toxicity and risk-free usage has actually been created abroad. Its formula is: 1000 grams of water, 30 grams of carboxymethyl cellulose (CMC), 250 grams of salt, N-methyl-2-pyridine 150 grams of ketone, 5 grams of surfactant ZooylFSN, as well as 53 grams of salt thioglycolate.

6. PVC safe heat stabilizer Commonly used door heat stabilizers are poisonous heavy metal salts, so PVC can not be used for food and medication product packaging. Nowadays, countries all over the world make use of the response product of isooctyl thioglycolate as well as organotin as a heat stabilizer. It is non-toxic as well as can be made use of as food and also medicine product packaging with good result.

7. Lubricant for PVC resin. Commonly utilized lubricating substances are paraffin, stearic acid and also its salts, stearic acid vinegar, silicone oil, and so on. Throughout mixing, they continue to deteriorate as well as fade, as well as make the resin color. A brand-new type of lubricant is made by responding Mercaptoacetic Acid with C30+α-olefin in the existence of dibenzoyl peroxide at 100 ° C for 2 hours. It is not just a lubricating substance, but likewise has the residential or commercial properties of warm stabilizer, thaw viscosity reducer as well as effective metal launch representative.

8. Corrosion-resistant zinc-manganese alloy electroplating bathroom elements for steel. This zinc-manganese alloy-plated steel plate and also steel pipeline established by Nippon Steel Pipe Co., Ltd. has exceptional deterioration resistance. The composition of the plating bath is: ZnSO4? 7H2070g/L, MnSO4?H2050g/ L, sodium citrate 180g/L, as well as thioglycolic acid 0 ~ 2.0 g/L. Electrolysis conditions: adverse electrode current density 30A/dm2, plating bath temperature 50 ° C, layering bath PH 5.6.

9. Layering bathroom elements throughout electrolytic transfer of trivalent chromium remedy. Due to severe side reactions on the electrodes throughout electrolytic transfer of trivalent chromium solution, troubles such as raw materials, tools, and procedures have not been dealt with, and also it has not been used. If thioglycolic acid is added to the plating bath, the trouble can be fixed, as well as a bright chromium finishing can be obtained.

10. Hair elimination agents: Skin lightening creams and hair elimination agents in cosmetics are specifically utilized to remove fine hair, beards, pubic hair, etc on the skin. Its major component is the salt of Mercaptoacetic Acid, such as calcium salt, barium salt, sodium salt, and so on 11. Others On top of that, there are lots of usages, such as skin whitening representative, acne representative, flotation protection zinc ore, preserved rawhide, rawhide hair elimination, sticky, hair dye powder, etc.

Mercaptoacetic Acid Preparation Method

1. Salt hydrogen sulfide method: chloroacetic acid and also sodium hydrogen sulfide respond under H2S gas at a stress of 8 or even more atmospheres. The reactants are treated with acid and afterwards cleaned with water, making use of solvents such as isopropyl ether, halobutyl urea, as well as butyl acetate. After removal, the solvent is removed from the remove, as well as the product is distilled under reduced pressure;

2. Salt thiocarbonate approach: Carbon disulfide reacts with sodium sulfide to create salt thiocarbonate, and after that responds with chloroacetic acid. After the reaction is full, break down with hydrochloric acid, heavy steam out CS2, extract with ether, eliminate the solvent, and distill under decreased stress. The yield is 85-92%.

3. Sodium polysulfide method: react sodium chloroacetate with salt polysulfide, acidify, minimize with zinc powder (granules), extract with ether, as well as boil down under lowered pressure.

4. Thiourea approach: Counteract chloroacetic acid with alkali to form salt chloroacetate, then heat it with thiourea to produce alkyl isothiourea, filter it, hydrolyze it with barium hydroxide to create barium thioglycolate, which is insoluble in water, filter it. The filter deposit is acidified with sulfuric acid to obtain the ended up item.


5. Bundt salt technique: Salt chloroacetate reacts with salt thiosulfate to create Bundt salt, which is hydrolyzed with acid. The produced thioglycolic acid is drawn out with a solvent such as diethyl ether (preferably isopropyl ether). The yield can get to 80 -85%, the main raw material intake per ton of 65% thioglycolic acid is (ton): chloroacetic acid 0.952, salt thiosulfate 2.30, zinc powder (320 mesh) 0.334, solid caustic soda 0.485, ether 1.0, sulfuric acid 4.35, nitrogen 17 bottles.

Mercaptoacetic Acid Precautions

Paths of intrusion: breathing, consumption, percutaneous absorption.
Carcinogen: The toxic impacts of this product might be associated with the unique effects of the thiol groups of specific enzymes. This product is extremely irritating. Eye contact might create severe damages, causing long-term loss of sight. Can cause skin burns; animate the skin and cause sensitive dermatitis. It can be absorbed via the skin as well as cause poisoning. If the 10% solution of this product is related to the skin of an animal <5mL/kg, it will create death.

Unintended leak actions
Rapidly evacuate personnel in the dripped infected location to a secure area, separate them, and strictly restrict accessibility. Cut off the fire source. It is advised that emergency situation -responders wear self-supporting favorable pressure respirators and acid and also alkali proof overalls. Do not come into straight contact with the leakage, cut off the source of the leak as high as possible, and also avoid it from going into limited areas such as sewers and also flooding ditches. Little leak: Usage sand or various other non-combustible products to soak up or take in. You can additionally rinse with large amounts of water, dilute the laundry water and placed it right into the wastewater system. Big leakage: develop dikes or dig pits to have leaks; cover with foam to minimize vapor dangers. Utilize a pump to move it to a tanker or special collector, and recycle or transfer it to a waste therapy website for disposal.

Protective procedures
Respiratory system defense: Self-priming filter gas masks (fifty percent masks) ought to be used when there is possible contact with its vapor. Throughout emergency situation rescue or discharge, it is recommended to wear self-contained breathing apparatus.
Eye security: Put on chemical shatterproof glass.
Protective clothes: Wear acid and alkali immune overalls.
Hand protection: Put on rubber acid as well as antacid resistant gloves.
Others: Cigarette smoking, consuming and drinking are prohibited in the workplace, and also hands should be washed before dishes. After work, shower and also change clothes. Store garments infected with poisonous substances independently and wash them for later on use. Keep good health behaviors.

Skin call: Remove polluted apparel and wash with a lot of running water for at the very least 15 minutes. Look for medical focus.
Eye contact: Right away lift eyelids and also rinse thoroughly with lots of running water or saline for a minimum of 15 minutes. Seek medical interest.
Inhalation: Move quickly to fresh air. Keep your airway open. If breathing is tough, give oxygen. If taking a breath quits, carry out mouth-to-mouth resuscitation instantly. Look for medical interest.
Ingestion: If ingested accidentally, rinse mouth with water and laundry stomach. Offer milk or egg white to consume. Look for clinical interest.
Fire extinguishing approaches: Fire extinguishing media: haze water, foam, sand.

About Products:
If you need the cosmetic raw material Mercaptoacetic Acid, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Mercaptoacetic Acid manufacturer and supplier, our company, ZSpharmac will provide Mercaptoacetic Acid raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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