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Mercaptoacetic Acid CAS 68-11-1

Molecular Formula: C2H4O2S

Formula Weight: 92.12

ZSpharmac: Mercaptoacetic Acid Cosmetic Raw Material Suppliers

Product Name: Mercaptoacetic Acid
CAS No: 68-11-1
Purity: 99%

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Basic Info

Product Name:Mercaptoacetic Acid
Other Names:Thioglycolic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Liquid
EINECS No.:200-677-4
Storage:Store at +2°C to +8°C.
Provide:Mercaptoacetic Acid MSDS;
Mercaptoacetic Acid COA

What is Mercaptoacetic Acid?

Mercaptoacetic acid, also known as thioglycolic acid, is an organic compound with the chemical formula HSCH2COOH. It belongs to the carboxylic acid class and is characterized by containing a carboxylic acid group (-COOH) and a sulfhydryl group (-SH). The thiol group is a reducing functional group that can participate in redox reactions, while the carboxylic acid group gives it acidity. Thioglycolic acid has a special smell due to the presence of its thiol group, and can serve as a ligand to form stable complexes with metal ions.

Mercaptoacetic Acid Property

Melting point 28 °C (lit.)
Boiling point 217 °C/150 mmHg (lit.)
density 1.097 g/mL at 25 °C (lit.)
vapor density 3.6 (vs air)
vapor pressure <0.98 atm ( 100 °C)
refractive index n20/D 1.477(lit.)
Fp 280 °F
storage temp. 2-8°C
solubility H2O: 1 M at 20 °C, clear, colorless
form Viscous Liquid or Low Melting Solid
color APHA: ≤15
Specific Gravity1.09
OdorMild ammoniacal; faint, fishy; characteristic.
PH11.0-12.0 (25℃, 1M in H2O)
pka8.88(at 25℃)
explosive limit2.1-10.6%(V)
Water Solubility MISCIBLE


Mercaptoacetic Acid Uses

Cosmetics and personal care products:
As a key ingredient in hair removal products, thioglycolic acid can penetrate the cuticle of hair and destroy the disulfide bonds in the hair, making the hair soft and easy to remove.
In hair care products, it is sometimes used as a conditioning agent to help repair damaged hair.

Chemical synthesis:
Intermediates: In organic synthesis, thioglycolic acid and its derivatives can be used as intermediates in the synthesis of other chemicals, especially in the preparation of sulfur-containing drugs, pesticides, dyes and spices.
Reducing agent: Due to its strong reducing property, thioglycolic acid can be used as a reducing agent to participate in chemical reactions, such as the reduction deposition of metal ions or the deoxygenation reaction in organic synthesis.

Analytical chemistry:
As a complexing agent, it is used for the analysis and determination of metal ions, such as complex titration of copper, lead, zinc, etc.
As a masking agent, it is used to eliminate the influence of interfering ions and ensure the accuracy of analysis.
Plant Growth Regulator: In some cases, thioglycolic acid is used as a plant growth regulator to affect plant growth and development.
Pesticide adjuvants: They are used as stabilizers or auxiliaries in certain pesticide formulations to enhance the effectiveness and stability of pesticides.

Metal processing and surface treatment:
Metal cleaning and corrosion inhibition: In metal surface treatment, thioglycolic acid can be used as a cleaning agent to remove oxide layers, and is also an effective additive for metal corrosion prevention.
Electroplating: In processes such as chemical gold plating and silver plating, it is used as a reducing agent or coordination agent to help the metal be deposited evenly and improve the quality of the coating.

Medicine and Biotechnology:
Drug synthesis: In the field of medicine, thioglycolic acid and its derivatives are starting materials for the synthesis of certain drugs, especially in synthetic pathways involving thiol reactions.
Protein modification: In biochemical research, thioglycolic acid can be used to modify proteins, such as changing the structure and function of proteins through thiolation reactions.

Environmental friendly:
Wastewater treatment: As a chelating agent for heavy metal ions, thioglycolic acid can help remove harmful heavy metal ions from industrial wastewater and purify water quality.

Prominent applications of Mercaptoacetic Acid in Cosmetics

Hair treatment:
Hair removal products: Thioglycolic acid is one of the key components of hair removal cream or liquid. Through its sulfhydryl group (-SH), it reacts with the disulfide bond (-S-S-) in the keratin in the hair, weakening the structural strength of the hair and making it The hair becomes soft and easy to remove, suitable for hair removal needs in all parts of the body.
Hair care repair: In some hair care products, thioglycolic acid uses its reducing properties to help repair damaged hair, especially protein structural damage caused by chemical perm and dyeing, and restore the smoothness of hair by rebuilding disulfide bonds. with luster.

Skin care:
Cuticle softening and renewal: In some exfoliation or deep cleansing products, the mild chemical ablation of thioglycolic acid can help soften dead skin cells, promote the renewal of the epidermis, and improve uneven skin tone and roughness.
Antioxidant function: Although it is not the main antioxidant component, the thiol part of thioglycolic acid can theoretically participate in antioxidant reactions, fight free radicals, and protect the skin from oxidative damage. Although its application in cosmetics is not as good as its use in hair removal and Notable in hair care.

Formula stabilizers and auxiliaries:
In cosmetic formulations, thioglycolic acid is sometimes used as a stabilizer or auxiliary to help improve product texture, improve compatibility with other ingredients, or as an auxiliary component of preservatives in some special formulations to enhance the stability of the overall formulation. .

Mercaptoacetic Acid Features

Chemical structure: The molecular formula of thioglycolic acid is C2H4O2S, which is structurally composed of an acetic acid (carboxylic acid) group and a mercapto group (-SH). This structure gives it both the acidity of carboxylic acid and the reducing and nucleophilicity of sulfhydryl groups.

Acidity: As a kind of carboxylic acid, thioglycolic acid shows a certain acidity and can release hydrogen ions (H+) to form anions (HSCH2COO-), which allows it to partially dissociate in water.

Reducing property: Thiol (-SH) is a key functional group of thioglycolic acid. It has strong reducing property and can participate in redox reactions, form stable complexes with metal ions, or serve as a reducing agent in organic synthesis.

Coordinating ability: The thiol and carboxylic acid groups of thioglycolic acid can form stable coordination bonds with metal ions, which makes it play an important role in the synthesis of metal complexes, extraction of metal ions, and analytical chemistry.

Reactivity: The mercapto group of thioglycolic acid can easily participate in addition reactions, substitution reactions and polymerization reactions, so it is often used as an intermediate in synthesis to construct more complex organic molecules, such as drugs, pesticides, dyes, etc.

Solubility: Thioglycolic acid has good solubility in water, which is beneficial to its application in aqueous media, such as cosmetic formulations, water treatment agents, etc.

Wide application: Based on its chemical properties, thioglycolic acid is widely used in cosmetics, pharmaceutical synthesis, metal surface treatment, textile industry, agriculture, water treatment, organic synthesis and other fields.


National Center for Biotechnology Information. PubChem Compound Summary for CID 1133, Thioglycolic acid. https://pubchem.ncbi.nlm.nih.gov/compound/Thioglycolic-acid. Accessed May 11, 2024.

As a company specializing in the production and supply of Mercaptoacetic Acid raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the Mercaptoacetic Acid raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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