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Menthone CAS 10458-14-7

Molecular Formula: C10H18O

Formula Weight: 154.25

ZSpharmac: Menthone Raw Material Supplier

Product Name: Menthone
CAS No: 10458-14-7
Purity: 99%

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Basic Info

Product Name:Menthone
Other Names:Menthone, Mixture of isoMers
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Liquid
EINECS No.:233-944-9
Storage:Room Temperature
Provide:Menthone MSDS;
Menthone COA

What is Menthone?

Menthone L-menthone (formula I), a normally taking place cyclic terpene ketone, is one of the primary elements of Asian mint and American mint oil; due to its cooling and refreshing impacts, it is commonly used in flavor solutions and condiments., and also extensively used in medicine. Racemic Menthone is also commonly made use of in the prep work of rejuvenating tastes. Therefore, the synthesis of menthone has actually constantly brought in people’s focus.

Menthone Property

Melting point 

-6 °C

Boiling point 

85-88 °C/12 mmHg (lit.)


0.896 g/mL at 20 °C (lit.)

refractive index 

n20/D 1.450


69 °C

storage temp. 

Sealed in dry,Room Temperature


Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.




Clear colorless



optical activity

[α]/D -7.0±5°, neat

Water Solubility 

Slightly soluble in water


Menthone Uses

Spices, utilized to prepare lavender, increased and other scents for cosmetics; mint-type flavors used for food, which are edible flavors allowed my country’s GB2760-1996; seasoning intermediates, utilized to manufacture thymol and menthol; additionally utilized as pharmaceutical basic materials.

CN200480031751.4 offers a fruit-containing food with mints and a sweetening base, which has no hefty sweetness triggered by the sweetening base and gives a rejuvenating feeling both during and after ingestion., and has high preference reputation. In addition to the fruit element and the sweetening base, it has elements (a) and (b):.

( a) One or more cooling substances chosen from the group including: menthol, menthone, camphor, pulegone, isopulegol, pulegone, cineole, pepper mint oil, pepper Peppermint oil, spearmint oil, eucalyptus oil and their isolates; and (b) several cold-sensing substances chosen from the team consisting of: 3-( 1-menthanthyloxy) -1, 2-propanediol, N-ethyl-p-menthane-3-carboxamide, 3-( 1-menthaneoxy) -2- methyl-1,2- propanediol, p-menthane-3,8- di Alcohol, 2-( 1-menthenyloxy) -1- ethanol, 3-( 1-menthenyloxy) -1- propanol, 4-( 1-menthenyloxy) -1- butanol, cyclo Formamide, acyclic formamide, N,2,3-trimethyl-2-isopropylbutanamide, menthyl alkoxyalkanol (the alkyl team includes 2 to 6 carbons), menthyl alkoxyalkyl Ethers (the alkyl group includes 1 to 6 carbons) and menthyl alkoxyalkanediol (the alkyl group contains 3 to 6 carbons). The innovator discovered that by adding cooling-sensing compounds such as menthol and cooling-sensing materials such as 3-( 1-menthol alkoxy) -1,2- propanediol to fruit juice-containing foods consisting of fruit components and sweetening bases, production of We have actually created a fruit juice-containing food that does not have residual hefty sweetness throughout and after ingestion, supplies a constantly revitalizing feeling, has high taste acceptability, and hinders also when saved under heating problems for a very long time. Decline in revitalizing sensation. The creators also located that these effects were not influenced by the kind of fruit juice-containing food.

Menthone Pharmacological Effects

Modern research shows that menthone has antiviral, anti-inflammatory, choleretic, and penetration-promoting results, and its thiosemicarbazone and semicarbazone derivatives likewise have anti-HIV-1 (B) and HIV-2 (POLE) results. Regarding the anti-inflammatory impact of menthone, it has actually been reported that it is related to its inhibition of the release of inflammatory factors in vitro.

With in vivo researches, Wang Feng et al. discovered that menthone pretreatment has a protective effect on endotoxin-induced swelling version computer mice. The impact is associated with preventing the release of various inflammatory factors, consequently lowering inflammatory cell seepage and inhibiting the pathological procedure of inflammatory response. The anti-inflammatory result may be connected to disrupting the activation of the NLRP3 inflammasome by changing ion channels, reducing lysosomal damage, or influencing NO launch.

Menthone Preparation

① Isolate from pepper mint oil.

② It can be prepared by utilizing p-3-ene as raw material, reacting with formic acid, further responding with potassium hydroxide, and ultimately acidifying with sulfuric acid.

③ It can be created by reducing pulegone or piperone as basic materials.

④ It can be created by using l-menthol as raw material and oxidizing it with chromic acid.

Include 1.24 g (0.008 mol) menthol and 20mL acetone right into a 100mL round-bottomed flask and mix with magnetic stirring to liquify. In a cold water bath, include 8ml of Jones’s reagent dropwise from the continuous pressure dropping funnel while stirring. During the dropwise enhancement, environment-friendly Cr2(SO4)3 precipitation can be seen. Add one more 25 mL of water and transfer to a separatory channel. Essence the organic phase two times with 10 mL of methylene chloride. Clean the natural phase with 5 mL of water. Combine the organic phases. Evaporate the solvent on a warm water bathroom and completely dry with anhydrous salt sulfate., that is, the crude item of L-menthone is gotten, and the yield is determined.

During the whole procedure, all the water phase is poured into the ready chromium waste fluid mug. Made use of glasses was cleaned 3 times with 5 mL of water each time and poured into the chromium waste mug. Include 1.5 times the theoretical amount (about 3.2 g) of sodium bisulfite to the accumulated chromium waste fluid (concerning 77mL) and mix continuously. Allow it represent 5 mins. It is observed that the waste liquid adjustments from orange to green, showing that Cr6+ in the waste fluid It has actually been totally reduced; readjust the pH worth to 8 with 6mol/L KOH service, let it stand for 12 hours to totally precipitate Cr3+ right into Cr(OH)3, filter it with suction, and utilize the DPCI technique to identify whether the chromium focus in the filtrate reaches the discharge requirement.

About Products:
If you need the cosmetic raw material Menthone, please contact our service staff directly, we will provide you with high-quality products at the best price.
Our company, as an experienced Menthone manufacturer and supplier, ZSpharmac will provide Menthone raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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