Zhishang Chemical

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Zhishang Chemical

Melatonin Pura CAS 73-31-4

Molecular Formula: C13H16N2O2

Formula Weight: 232.28

ZSpharmac: Melatonin Pura Supplement

Product Name: Melatonin Pura
CAS No: 73-31-4
Purity: 99%

Basic Info

Product Name:Melatonin Pura
Other Names:Melatonine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Pharmaceutical Raw Materials
Appearance:White to off-White Powder
EINECS No.:200-797-7
Provide:Melatonin Pura MSDS;
Melatonin Pura COA

What is Melatonin Pura?

Melatonin Pura is an indispensable all-natural hormone in the body, which manages and also affects the secretion of various other different hormonal agents. When Melatonin Pura in the body decreases, numerous functions of the human body will certainly be impacted, as well as different conditions will adhere to. Studies have shown that the secretion of Melatonin Pura in the human body starts to reduce after midlife, and also its secretion is minimal in old age. Supplementing sufficient Melatonin Pura immediately can improve the feature of the endocrine system, boost resistance, boost anti-stress as well as antioxidant features, improve sleep, decrease the rate of human aging, and also reduce the price of deterioration of sex-related body organs; Melatonin Pura can likewise aid prevent cancer cells It is specifically helpful for regular sleeplessness.

Melatonin Pura Properties:

Melting point 116.5-118 °C (lit.)
Boiling point 374.44°C (rough estimate)
density 1.1099 (rough estimate)
refractive index 1.6450 (estimate)
Fp 9℃
storage temp. -20°C
solubility Soluble in ethanol to at least 50mg/ml
form Powder
color white to off-white


Melatonin Pura Uses

  1. Melatonin Pura is a hormonal agent produced by the pineal gland. Melatonin is very conserved, a non-receptor complimentary radical scavenger as well as broad-spectrum antioxidant. Melatonin Pura aids protect against ischemia-reperfusion injury in the liver, mind, heart muscular tissue, digestive tract, and also kidneys. Melatonin Pura can be widely used in health food, medication, all kinds of cosmetics, beneficial care items. Function: 1. Melatonin Pura gets rid of freckles and also whitens naturally: Melatonin Pura lightens up the skin. It can manage the endocrine of the body, get rid of dark areas, age spots, chloasma, maternity spots and coloring caused by sunlight direct exposure, whiten and also hydrate the skin, as well as restore vibrant temperament. 2. Effectively enhance rest: Suitable supplements of melatonin can successfully improve rest high quality. 3. Longevity: Melatonin Pura is the most important high-efficiency endogenous anti-oxidant in the brain, which has a safety result on the brain. Therefore, Melatonin Pura is an important anti-aging hormonal agent. 4. Keep as well as enhance sexual feature: Supplementing with Melatonin Puracan enhance the sex-related feature of middle-aged as well as senior people that deal with physical frailty as well as reduced power, causing loss of libido.
  2. Melatonin Pura is used in medications and also health and wellness products to improve the body’s immune feature, prevent aging as well as bring back youth, and is an all-natural “resting tablet”.
  3. Melatonin Pura is a hormonal agent secreted by the pineal body of the pituitary gland in the body. The amount of this hormone secreted is associated with light. The weaker the light, the extra secreted it is. On the other hand, the less it is to assist rest.

Physiological Effects of Melatonin Pura

1.Impacts on the brain: Melatonin Pura soaked up by the mind is focused in the midbrain and hypothalamus, which boosts the activity of mind pyridoxal kinase, thereby promoting the decarboxylation of glutamic acid to form γ-aminobutyric acid, as well as the decarboxylation of serotonin to develop Serotonin, the increased web content of these 2 repressive neurotransmitters, has a regulating and sedative result on the central nerve system.
2. Partnership with gonads: Pineal hormonal agent has an inhibitory result on the reproductive system. Clinically, pineal principal cell growths can result in delayed adolescence, while pineal teratoma can be made complex by precocious puberty as a result of the exclusion of principal cells. Ambient light and considerate nerves can impact reproductive system function by managing the synthesis as well as release of melatonin from the pineal gland.
3.Connection with thyroid: Melatonin Pura is offered, the secretion of thyroid hormone is reduced, which may be by inhibiting the release of TRH in the hypothalamus and also the secretion of thyroid-stimulating hormone (TSH) in the pituitary, thereby inhibiting thyroid function.
4.When injecting pineal gland extracts into healthy people, the secretion of aldosterone and the excretion of 17 ketone steroids decrease.
5.Relationship with pancreatic islets: Pineal hormone can lead to decreased blood sugar and increased glucose tolerance. To sum up, the pineal gland can assist the pituitary in regulating the endocrine function together, and it plays an important role in maintaining the relatively constant internal environment of the body and controlling some endocrine functions, especially the gonads.

Synthesis and Release of Melatonin Pura Hormone

Melatonin Pura take tryptophan from the blood circulation and convert it to 5-hydroxytryptophan under the catalysis of hydroxylase, which is decarboxylated to serotonin by decarboxylase. There are three possible transformations of serotonin: a part is decarboxylated by monoamine oxidase. Amine becomes 5-hydroxy-indoleacetic acid; another part leaves the pineal cell and is taken up by sympathetic nerve terminals and stored together with the neurotransmitter norepinephrine; a third part is acetylated by N-acetyl serotonin transferase It is then o-methoxylated by oxindole-o-methyltransferase to form melatonin. After the synthesis of melatonin, it may be released by cells into the blood circulation or enter the blood circulation through the cerebrospinal fluid. Norepinephrine can enhance its synthesis, and its speed depends on the activity of hydroxylase in the liver cell microsomes. Under the catalysis of this enzyme, the formation of 6 – Hydroxymelatonin, which is subsequently excreted in urine in combination with glucuronic acid and sulfate.

Melatonin Pura Dosage and Applicable Population


Melatonin Pura MT1 and MT2 receptors are very prone to “desensitization,” a significant decline in activity following direct exposure to dosages of the hormone above normal focus. When people get wellness items that can have Melatonin Pura, they need to clarify its single-dose spec. If you bought a tablet, you can take it apart. It is advised to begin with a little dose, 0.1mg-0.3 mg melatonin can enhance sleep, and also 0.3mg-0.5 mg Melatonin Pura can enhance sleep problems brought on by body clock disorders. Long-term use high dosages of Melatonin Pura need to be prevented unless suggested by a physician to decrease the opportunity of creating Melatonin Pura resistance.

For people:

One classification is people who require jet lag and changes. This populace has difficulty sleeping as well as getting up because of inconsistencies in circadian rhythms as well as expected sleep as well as work hours. Rest and also wake times can be changed by supplementing exogenous Melatonin Pura. The various other group is middle-aged and senior people. With age, the pineal gland gradually diminishes till it becomes calcified, and also the equivalent secretion of Melatonin Pura decreases, leading to a weakening of the rhythm of the biological clock, causing lowered rest as well as very early awakening. By supplementing Melatonin Pura, it can promote sleep and also strengthen rest.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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