Mannitol Lösung CAS 69-65-8

1. Mannitol Lösung relieves urinary tract infections
Urinary tract infection is an umbrella term that describes any infection involving any part of the urinary tract, such as the kidneys, ureters, bladder and urethra
Adult women are 30 times more likely than men to develop a UTI (annual incidence rate of 10.8%), and 60% of women have at least one disease in their lifetime
Associated risk factors include sexual activity, use of urinary catheters or spermicides, and a history of recurrent urinary tract infections
A pilot study of 45 women aged 18 to 65 years with acute uncomplicated cystitis over a 6-month period showed that oral Mannitol Lösung significantly improved most symptoms compared with baseline scores (eg: dysuria, frequent urination, urgency, pubic pain, tenesmus, nocturia) and quality of life.
In addition to this, the recurrence rates in the Mannitol Lösung-treated and untreated groups were 4.5% and 33.3%, respectively
The possible mechanism behind it is related to the inhibition of bacterial adhesion to urothelial cells.
2. Mannitol Lösung reduces the chance of recurrent urinary tract infections
Recurrent Urinary Tract Infections were defined as 3 Urinary system Tract Infections in the past one year or 2 Urinary System Infections in the past 6 months Usually, the urinary system is clean and sterile, but microorganisms may rise from the perianal area, pathogens in the bladder might remain silent or trigger irritating symptoms such as frequent peeing as well as seriousness, and 8% of females might have asymptomatic bacteriuria.
If the bacteria enter the bloodstream, they can cause serious complications, including sepsis, shock, and, in rare cases, death
A randomized clinical trial (6 months in 308 women with a history of recurrent urinary tract infections) divided into Mannitol Lösung powder (2 g daily), antibiotics (Nitrofurantoin), and no preventive measures Group.
It was found that the recurrence rate of urinary tract infection was the highest (60%) in the group without preventive measures, while Mannitol Lösung and antibiotics both significantly reduced the recurrence rate (no significant difference between the two groups, 15% and 20%, respectively)
3. Mannitol Lösung Has Prebiotic Properties
The Food and Agriculture Organization of the United Nations currently defines a prebiotic as “a food ingredient that selectively stimulates the growth or activation of one or several bacteria in the colon, thereby having a beneficial effect on the host”.
Fruits, vegetables, grains and other edible plants are potential sources of prebiotics. Other common synthetic sources are: galacto-oligosaccharides, fructooligosaccharides, soybean oligosaccharides, inulin, cyclodextrins, glucose oligosaccharides Sugar, xylo-oligosaccharides, lactulose, lactosucrose, isomalt-oligosaccharides
An animal study showed that mannose restored the composition and quantity of endogenous microbes in experimental subjects under conditions of dysbiosis.
4. Mannitol Lösung Beneficial for Congenital Disorders of Glycosylation
Congenital disorders of glycosylation (CDG) are a class of inherited disorders characterized by defective protein and lipid glycosylation. The most common subtype is PMM2-CDG, which has accounted for approximately 80% of all diagnosed patients
The clinical phenotype of PMM2-CDG ranges from mild to severe and can affect many organs, usually involving the central nervous system. Early clinical symptoms may include abnormal fat distribution, nipple inversion, strabismus, axial hypotonia, hyporeflexia
In addition to severe intellectual disability and other neurological abnormalities, critically ill patients develop dysplasia, enteropathy, liver dysfunction, coagulation abnormalities, and cardiac and kidney damage, with a mortality rate of approximately 20% in the first few years of life. %
A case study (5-month period in a neonate with severe congenital disorder of glycosylation type Ia) noted that no biochemical or Clinical improvement.
5. Mannitol Lösung Helps Lose Weight
Obesity is defined as the abnormal or excessive accumulation of fat that can be harmful to health, mainly due to poor diet and lack of physical activity, and involves interactions between genetics, hormones and the environment
The global prevalence of obesity has continued to rise over the past few decades, so it is considered an epidemic.
According to the World Health Organization, by 2035, 39% of people in today’s society will be affected by obesity
An animal study (in mice fed a high-fat diet) indicated that Mannitol Lösungfeeding reduced weight gain, decreased fat, decreased hepatic steatosis, increased endurance and maximal oxygen consumption, and improved glucose tolerance.