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Mannitol Lösung CAS 69-65-8

Molecular Formula: C6H14O6

Formula Weight: 182.17

ZSpharmac: Mannitol Lösung Supplement

Product Name: Mannitol Lösung
CAS No: 69-65-8
Purity: 99%

Basic Info

Product Name:Mannitol Lösung
Other Names:D-Mannitol
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Organic Chemical Raw Materials
Appearance:White Crystalline Powder
EINECS No.:200-711-8
Provide:Mannitol Lösung MSDS;
Mannitol Lösung COA

What is Mannitol Lösung?

Mannitol Lösung is a monosaccharide structurally pertaining to glucose, associated with countless metabolic procedures, specifically in the glycosylation of particular proteins, and plays an important function in lots of cells as well as body organs. In nature it exists in pets, plants as well as microorganisms. Some vegetables and fruits include percentages of Mannitol Lösung, including: cranberries, apples, oranges, peaches, cauliflower, green beans.

Mannitol Lösung Properties:

Melting point 167-170 °C(lit.)
alpha 141 º (c= USP-directives)
Boiling point 295°C
density 1.52
refractive index 1.3330 (estimate)
Fp 290-295°C/3.5mm
storage temp. 2-8°C
solubility H2O: 1 M at 20 °C, clear, colorless
form Crystalline Powder
pka13.5(at 18℃)
color White
PH5.0-6.5 (25℃, 1M in H2O)
optical activity[α]25/D +23.3 to +24.3°(lit.)
Water Solubility soluble


Mannitol Lösung Uses

1. Mannitol Lösung relieves urinary tract infections
Urinary tract infection is an umbrella term that describes any infection involving any part of the urinary tract, such as the kidneys, ureters, bladder and urethra
Adult women are 30 times more likely than men to develop a UTI (annual incidence rate of 10.8%), and 60% of women have at least one disease in their lifetime
Associated risk factors include sexual activity, use of urinary catheters or spermicides, and a history of recurrent urinary tract infections
A pilot study of 45 women aged 18 to 65 years with acute uncomplicated cystitis over a 6-month period showed that oral Mannitol Lösung significantly improved most symptoms compared with baseline scores (eg: dysuria, frequent urination, urgency, pubic pain, tenesmus, nocturia) and quality of life.
In addition to this, the recurrence rates in the Mannitol Lösung-treated and untreated groups were 4.5% and 33.3%, respectively
The possible mechanism behind it is related to the inhibition of bacterial adhesion to urothelial cells.
2. Mannitol Lösung reduces the chance of recurrent urinary tract infections
Recurrent Urinary Tract Infections were defined as 3 Urinary system Tract Infections in the past one year or 2 Urinary System Infections in the past 6 months Usually, the urinary system is clean and sterile, but microorganisms may rise from the perianal area, pathogens in the bladder might remain silent or trigger irritating symptoms such as frequent peeing as well as seriousness, and 8% of females might have asymptomatic bacteriuria.
If the bacteria enter the bloodstream, they can cause serious complications, including sepsis, shock, and, in rare cases, death
A randomized clinical trial (6 months in 308 women with a history of recurrent urinary tract infections) divided into Mannitol Lösung powder (2 g daily), antibiotics (Nitrofurantoin), and no preventive measures Group.
It was found that the recurrence rate of urinary tract infection was the highest (60%) in the group without preventive measures, while Mannitol Lösung and antibiotics both significantly reduced the recurrence rate (no significant difference between the two groups, 15% and 20%, respectively)
3. Mannitol Lösung Has Prebiotic Properties
The Food and Agriculture Organization of the United Nations currently defines a prebiotic as “a food ingredient that selectively stimulates the growth or activation of one or several bacteria in the colon, thereby having a beneficial effect on the host”.
Fruits, vegetables, grains and other edible plants are potential sources of prebiotics. Other common synthetic sources are: galacto-oligosaccharides, fructooligosaccharides, soybean oligosaccharides, inulin, cyclodextrins, glucose oligosaccharides Sugar, xylo-oligosaccharides, lactulose, lactosucrose, isomalt-oligosaccharides
An animal study showed that mannose restored the composition and quantity of endogenous microbes in experimental subjects under conditions of dysbiosis.
4. Mannitol Lösung Beneficial for Congenital Disorders of Glycosylation
Congenital disorders of glycosylation (CDG) are a class of inherited disorders characterized by defective protein and lipid glycosylation. The most common subtype is PMM2-CDG, which has accounted for approximately 80% of all diagnosed patients
The clinical phenotype of PMM2-CDG ranges from mild to severe and can affect many organs, usually involving the central nervous system. Early clinical symptoms may include abnormal fat distribution, nipple inversion, strabismus, axial hypotonia, hyporeflexia
In addition to severe intellectual disability and other neurological abnormalities, critically ill patients develop dysplasia, enteropathy, liver dysfunction, coagulation abnormalities, and cardiac and kidney damage, with a mortality rate of approximately 20% in the first few years of life. %
A case study (5-month period in a neonate with severe congenital disorder of glycosylation type Ia) noted that no biochemical or Clinical improvement.
5. Mannitol Lösung Helps Lose Weight
Obesity is defined as the abnormal or excessive accumulation of fat that can be harmful to health, mainly due to poor diet and lack of physical activity, and involves interactions between genetics, hormones and the environment
The global prevalence of obesity has continued to rise over the past few decades, so it is considered an epidemic.
According to the World Health Organization, by 2035, 39% of people in today’s society will be affected by obesity
An animal study (in mice fed a high-fat diet) indicated that Mannitol Lösungfeeding reduced weight gain, decreased fat, decreased hepatic steatosis, increased endurance and maximal oxygen consumption, and improved glucose tolerance.

Mannitol Lösung Other Apps

1. For the preparation of Maohejue granules

CN201711453974.5 provides a kind of Rhizoma Rhizoma granules, the components of which include Rhizoma Rhizoma root extract, lotus leaf extract, Cassia seed extract, dandelion extract, Raisin seed extract, maltodextrin and Mannitol Lösung.

The weight ratio of the above-mentioned Maohejue granules is as follows: Rhizoma Rhizoma root extract: lotus leaf extract: Cassia seed extract: Dandelion extract: Raisin seed extract: Maltodextrin: Mannitol Lösung is 1.8 to 2.1: 1.8-2.2: 1.8-2.2: 1.8-2.1: 1.8-2.1: 22-27: 10-14, wherein the preferred ratio is Rhizoma chinensis extract: lotus leaf extract: cassia extract: dandelion extract: radish extract :Maltodextrin:Mannitol Lösung is 2:2:2:2:2:25:12. Another object of the present invention is to provide the application of Maohejie granules in the preparation of slimming medicines. The Maohejue granules of the invention have obvious weight loss effect, have the effect of reducing weight, are safe and have no side effects. The invention adopts pure natural plant extract as raw material, has unique formula, reasonable proportion, easy-to-obtain raw materials, simple preparation process, convenient use, good curative effect, safety and hygiene, low cost, and has broad market prospect.

2. For the preparation of a prebiotic for gastrointestinal conditioning

Prebiotics refer to non-digestible food components, which have beneficial effects on the host by selectively stimulating the growth and activity of one or more bacteria, thereby improving the health of the host. Prebiotics mainly include various oligosaccharides or oligosaccharides (composed of 2 to 10 molecular monosaccharides). A more general term is functional oligosaccharides. CN201710705676.4 provides a prebiotic for gastrointestinal conditioning and a preparation method thereof. The prebiotic uses plant raw materials such as mulberry powder, Moringa powder and the like as main components, so as to achieve the effect of conditioning the stomach.

In order to achieve the above object, the technical scheme adopted in the present invention is as follows: a prebiotic for gastrointestinal conditioning, the tablet selects mulberry fruit powder as the main component, is equipped with Mannitol Lösung, fructooligosaccharide, Moringa powder, Poria water extract , Coix seed water extract, xylitol, corn starch prepared; the proportion of each component by weight is as follows: 20-30 parts of mulberry powder, 10-15 parts of Mannitol Lösung, 5-8 parts of fructooligosaccharides parts, 20-30 parts of Moringa powder, 5-8 parts of Poria cocos water extract, 5-8 parts of Coix seed water extract, 5-7 parts of xylitol, 10-15 parts of corn starch.

A method for preparing the above-mentioned prebiotics for gastrointestinal conditioning, the method comprising the following steps: 1) sieving: taking mulberry fruit powder, Mannitol Lösung, fructooligosaccharides, moringa powder, xylitol, and corn starch, respectively Pass through a 120-mesh sieve, and take the sieved part for later use; 2) Weighing: weigh 20-30 parts of mulberry fruit powder sieved in step 1), 10-15 parts of D-mannitol, low 5-8 parts of polyfructose, 20-30 parts of Moringa powder, 5-7 parts of xylitol, 10-15 parts of cornstarch, in addition, weigh 5-8 parts of Poria cocos water extract, Coix seed water 5-8 parts of the extract; 3) Mixing: Mix and stir the mulberry fruit powder, Mannitol Lösung, fructooligosaccharide, Moringa powder, xylitol, and corn starch weighed in step 2) for 15-25 minutes to obtain the raw material Mixed powder; 4) High-efficiency wet mixing and granulation: add the raw material mixed powder obtained in step 3) into the high-efficiency mixing wet granulator, set the mixing speed of the stirring paddle to 200-400 rpm, and the cutting speed of the shearing paddle to be 2500- 3500rpm, the pressure of the compressed air source is 0.4-0.6MPa, add the Poria cocos water extract and Coix seed water extract weighed in step 2) into the raw material mixed powder and stir and granulate for 15-25min; 5) Drying: Step 4 ) The prepared wet granules are placed in an oven, and dried at a temperature of 60-70° C. until the moisture content of the granules is less than 5.0%; 6) Tabletting is performed with a rotary tableting machine. The preparation process of the invention is simple, the natural medicinal properties of the raw materials can be ensured, and the beneficial effect of regulating the stomach and intestines can be achieved by mixing with each other, and it is a targeted health care product.

Mannitol Lösung Safety Precautions

1. Not to be used by pregnant and lactating women (due to unknown safety)

2. Long-term intake of high doses may cause kidney damage

3. Although Mannitol Lösung may be beneficial for urinary tract infections, the current evidence is not very strong, and people with related diseases should still consult a doctor first to avoid delaying the condition.

4. Since Mannitol Lösung is a form of sugar (which may stimulate insulin secretion), please use it with caution in people with diabetes or those taking hypoglycemic drugs, and monitor blood sugar regularly

5. Do not use with antibiotics: Pradimicin may affect the efficacy of the drug

6. Patients with small intestinal bacterial overgrowth (SIBO) have a higher chance of side effects after use, please pay attention

7. Those who have been allergic to grains or fruits, please use it with caution, as it may induce allergic reactions.

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Mannitol Lösung Quotation