Zhishang Chemical

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Zhishang Chemical

Lecithine CAS 8002-43-5

Molecular Formula: C42H80NO8P

Formula Weight: 758.06

ZSpharmac: Lecithine Supplier

Product Name: Lecithine
CAS No: 8002-43-5
Purity: 99%

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Basic Info

Product Name:Lecithine
Other Names:Lecithin
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Pale Brown to Yellow Solution
EINECS No.:232-307-2
Provide:Lecithine MSDS;
Lecithine COA

What is Lecithine?

Lecithine, furthermore described as phosphatidylcholine, is a lipid created by the dehydration condensation of glycerol, fat (2 particles), phosphoric acid and choline. The fat chain in the particle is filled along with unsaturated, as well as it is a non-polar hydrophobic tail; phosphoric acid The choline part is a dipolar ion, which is a polar hydrophilic head, and is described as the “third nutrient” after healthy protein as well as vitamins. It is the product basis of life and the basic material of numerous membrane structures of cells. It exists in every cell, and also is extra concentrated in the liver, mind, heart, kidney and also immune system. It is synthesized by the liver in the human body, and food generally exists in soybeans., egg yolk.

Lecithine’s English Lecithin means “yolk”. Lecithine is an essential anti-aging material. It connects with proteins to develop lipoproteins, which can not just improve the quality of food, however additionally improve the features of cardiovascular, cerebrovascular and also nervous systems. It can control blood lipids, stop vascular sclerosis, protect the liver, stop Alzheimer’s condition, reinforce the mind and also boost intelligence, protect against as well as solve the formation of gallstones, increase the activity of cellular superoxide dismutase (SOD), strengthen the ability of cells to feed on complimentary radicals, minimize The manufacturing of lipid peroxide can break down contaminants in the body. As a result of its hydrophilicity, it can boost the function of hemoglobin as well as make the skin smooth and soft. The inositol included in it is the standard element of skin as well as hair health care, which can advertise blood circulation. Promote hair regrowth, prevent hair graying, worthwhile of being an anti-aging guardian.

Lecithine Property

Melting point >145°C (dec.)
density d424 1.0305
Fp 57 °C
storage temp. -20°C
solubility chloroform: 0.1 g/mL, slightly hazy, slightly yellow to deep orange
form solution
color Pale Brown to Yellow
Water Solubility NEGLIGIBLE


Lecithine Uses

  1. Lecithine is a nutritional medication. For the avoidance of atherosclerosis, hypertension, cardiovascular disease, Alzheimer’s disease, gout arthritis, diabetes, neurasthenia. It can likewise be used for the preparation of bacterial society tool. Phospholipids are effective emulsifiers, which can “emulsify” cholesterol and fat right into incredibly fine fragments, as well as also liquify the “atherosclerotic plaques” that have actually been formed, thereby decreasing blood lipids and also decreasing the possibilities of stroke and myocardial infarction. As an emulsifier, phospholipids can additionally assist the human body absorb fat-soluble vitamins A, D, E, K, etc for the regular performance of the human body. Note that the effects of different preparations are various.
  2. Lecithine is used as resources for natural food, emulsifier, top quality improver, emulsifier for injection as well as liposome basic material.
  3. Lecithine can successfully boost and prevent arteriosclerosis, hypertension, heart disease and stroke, while improving cell vitality and controling the nerves.
  4. Lecithine is made use of as an artificial additive, and also base is made use of as a feed additive. It is additionally used in medicine, cosmetics, as well as emulsifier for natural leather as well as asphalt.

Lecithine Action

There are 60 trillion cells that comprise the human body. 500,000 will pass away in 1 second, as well as 500,000 will be restored at the same time. As we age, even more cells die as well as fewer cells regenerate. When the variety of cell death is higher than the number of regrowth, a person begins to age. The metabolic process of cells is regulated by the cell membrane layer. The health and wellness of the cell membrane is directly related to the cell’s self-repair capability, details transmission capability, capacity to stand up to outside aggression, cell task as well as regeneration ability. The cell membrane is mostly composed of lecithin. Supplementing the body with Lecithine indicates that the harmed cell membrane can be fixed, the function of the cell membrane layer can be boosted, the cell membrane layer can be softened and also invigorated, and also the cell task can be enhanced. With the intake of Lecithine, the metabolic capacity, self-healing capability and also the regeneration ability of the antibody cells can be enhanced, the vitality of the body can be enhanced, as well as the aging of the human body can be basically delayed.

Lecithine can emulsify and also decompose fat, as well as can emulsify cholesterol as well as fat attached to the capillary wall surface right into great particles, which are liquified in the blood and delivered back to the liver for metabolic process. It can soften blood vessels, boost serum lipids, get rid of peroxides, lower the web content of cholesterol as well as fat in blood, thereby minimize blood viscosity, boost blood circulation, and decrease the retention time of fat in capillary. Furthermore, the nutrient-rich, oxygen-rich blood moves unobstructed to the mind, heart and various other body organs. The Department of Food and Nourishment of Keio College School of Medication has actually performed scientific experiments and ended that taking Lecithine can successfully reduce excessive blood lipids and cholesterol, thus protecting against and also treating coronary cardiovascular disease, hypertension, coronary infarction, analytical apoplexy, cerebral hemorrhage, Arteriosclerosis as well as other conditions.

Lecithine can offer enough nourishment for mind afferent neuron to speed up the transmission of information in between the mind nerves, consequently boosting brain vigor, removing mind exhaustion, making brain reasoning quicker, as well as enhancing knowing as well as job efficiency. Lecithine can keep the typical feature of mind nerve cells while repairing harmed brain cells and also opening up the barriers between the brain and also blood circulation, as well as improve the function of the brain nerve system, therefore attaining the effect of stopping Alzheimer’s disease.

Hefty alcohol consumption or excess nourishment can raise the worry on liver cells and lower the liver’s capability to synthesize phospholipids. When there wants phospholipid choline in the body, it will certainly cause a huge quantity of fat build-up in the liver, forming fatty liver, destroying liver cells, reducing liver feature, causing liver cirrhosis and also liver cancer cells. It has actually been scientifically proven that lecithin supplements can improve the metabolic process of liver cells, promote fat deterioration, safeguard the liver, as well as protect against the occurrence of fatty liver and various other diseases.

Lecithine can boost the function of the pancreatic, fix the cells of the pancreatic, make it secrete adequate insulin, lower blood sugar, and also successfully move the sugar in the blood to the cells, consequently minimizing the problem of diabetes mellitus.

Lecithine can advertise the transmission of spirit, improve brain vigor, and as a result of its excellent emulsifying residential properties, it can successfully prevent cholesterol from precipitating on the blood vessel wall surface and also eliminate part of the sediment, thus lowering serum cholesterol, lowering blood viscosity, advertising blood circulation, and preventing cardiovascular disease. The function of vascular condition. For that reason, normal intake of items including soy lecithine can properly manage blood lipids and also cholesterol, boost brain feature, improve memory, and avoid the event of different illness.

Production Method of Lecithine

Method 1. Extract cholesterol and cephalin from the mind stem. The mind stem is soaked in 3 times of acetone for 20-24 hrs, mixed continuously, filtered, as well as the filtrate is used to prepare cholesterol. The filter cake is vacuum-dried, 2-3 times the quantity of ethanol is added, extracted 4-5 times, filtered, and also the precipitate is vacuum-dried to prepare cephalin, as well as the filtrate is vacuum-concentrated to acquire a concentrate.
Preparation of Lecithine Final product concentrate, include half the amount of ether, allow mean 2 hours, precipitate and filter to get a clear liquid, add acetone under fast mixing, precipitate, filter, accumulate the lotion, wash two times with acetone, vacuum completely dry, Obtained lecithin ended up product
Concentrate [diethyl ether] → [2h] made clear service [acetone] → lecithin ended up product.

Technique 2, utilizing sheep mind as basic material
Cholesterol was drawn out from fresh lamb mind, minced, immersed in acetone (3 times, 2.5 times, 1.5 times) for 3 times, 24 hr each time, mixed, filteringed system and pushed, the filtrate was made right into cholesterol, as well as the filter cake was dried out.
Essence, dissolve, focus the filter cake and include ether (3 times the quantity, 2.5 times the quantity, 1.5 times the amount) to remove 3 times, each 24h, stir, filter to obtain the filtrate, concentrate to acquire the concentrate Add a percentage of ethanol, heat to dissolve, speed up in a cold room for 24 hours, accumulate the precipitate, soak in ethanol for 3-4 times in a cool place, 3 times the quantity each time, heat to dissolve, cool down, speed up for 24 hours, and also pour out the supernatant. The supernatant was focused in vacuo to acquire a concentrate.
Filter cake [diethyl ether] → filtrate [concentration] → concentrate [ethanol] → supernatant [focus] → concentrate.
Prep Work of Lecithine End product Concentrate was included with half the quantity of ether under continuous mixing, represented 2h, filtered to obtain ether clear liquid, included ether clear liquid to acetone under fast stirring, sped up out, filteringed system, as well as cleaned the precipitate with acetone twice, vacuum cleaner drying to get lecithin ended up item
Concentrate [ether] → clear liquid [acetone] → lecithin completed product.

Method 3. Using yeast as basic material
Preparation of paste: Pass completely dry yeast powder via a 60-80 mesh filter, include 3 times the quantity of 82% -84% ethanol to remove for 18-24 hrs, maintain 70 ° C for 3 hrs, maintain stirring, allow cool down to below 30 ° C and filter, filter deposit After that essence twice, shake off ethanol, integrate the removes, concentrate in 70 ℃ vacuum cleaner, the concentration time is not greater than 24h, get paste. The filter deposit is used to extract ribonucleic acid as well as zymosan.
Dry yeast or Geotrichum candidum [ethanol, initially 70 ℃, after that 30 ℃] → extract [70 ℃] → paste.
Preparation of concentrate: Include 5% -10% water to the paste, include 3-5 times the amount of ether, mix vigorously for 2-3h, let represent 16-20h, throw out the center as well as reduced layers, and also save the top ether at -5 ° C Area in the fridge for 20-24h, the ergosterol crystallizes out, filter, boil down the filtrate, recover about 1/2 ether, then position it in the -5 ° C fridge for 18-22h, include anhydrous salt sulfate, filter to get ether filtrate, and distill Add regarding 2/3 ether to get a concentrate.
Paste [WATER, ether] → [Na2SO4] filtrate [purification] → concentrate.
Prep work of ethanol supernatant concentrate Add 3-5 times the amount of acetone, stir while adding, leave for some time after including, pour out the mixed remedy of ether as well as acetone, clean with anhydrous acetone 3-4 times to acquire a precipitate, include 2 times the amount of anhydrous ethanol, heated to 70 ℃, stirred for 1-2 hrs to dissolve, and entrusted to stand in the cold store to pass the fluid. The ethanolic supernatant was decanted and also precipitated as crude coagulation.
Prep Work of Lecithine End Product Distill the ethanol supernatant, recuperate the ethanol, obtain the precipitate, include anhydrous ether, stir, liquify, allow stand for 7 days, take in the supernatant, add 1.5 times the amount of acetone to speed up the precipitate, pour out the acetone, clean Precipitate 3-4 times, add ethanol to liquify at 70 ° C, as well as dry to get the ended up item of lecithin.
Ethanol supernatant [distillation] → precipitate [diethyl ether] → supernatant [acetone, ethanol] → lecithin ended up product.

Technique 4. Using the mind and spine as raw materials.
Extraction of cholesterol and also Lecithine Take fresh or frozen mind or spine, remove membranes and also blood veins and other impurities, mince them, impregnate them with 1.2 times the quantity of acetone for 4.5 hrs, mix continually, filter, and also repeat for 5 times, and the filtrate is utilized to prepare cholesterol. The filter cake was vacuum-dried, 2-3 times the amount of ethanol was added, extracted at 35-40 ° C. for 12 h, filtered, and also removed once again, the filter cake was vacuum-dried to prepare cephalin, and the filtrate was made use of to prepare lecithin.
Preparation of Precipitate Concentrate the filtrate to 1/3 quantity in vacuo to obtain a concentrated service, placed it in a chilly space overnight, filter, add a saturated service of cadmium chloride to the filtrate, speed up, filter, gather the precipitate, add 2 times the quantity of ether, shake, The ether was gotten rid of by centrifugation and also this was duplicated 8-10 times to gather the precipitate.
Filtrate [concentrated] → focused remedy [cadmium chloride, ether] → precipitate.
Prep work of concentrate Include 4 times the quantity of chloroform to the precipitate, tremble to acquire a remedy (turbid), include 25% ammonia methanol solution, precipitate, centrifuge, and focus the centrifuge in vacuum to dry skin to get a concentrate.
Precipitate [Chloroform] → Liquifying solution [Ammonia methanol service] → Concentrate.
Prep Work of Lecithine Finished product Concentrate is included with anhydrous ether, concentrated in vacuo, repeated two times to remove water to obtain a concentrate, add a small amount of ether, put it right into acetone, stand, filter, accumulate the precipitate, vacuum cleaner completely dry to obtain lecithin ended up item.
Concentrate [anhydrous ether] → concentrate [diethyl ether, acetone] → Lecithine ended up product.

About Products:
If you need Lecithine, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Lecithine manufacturer and supplier, ZSpharmac will provide Lecithine raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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