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LDAO CAS 1643-20-5

Molecular Formula: C14H31NO

Formula Weight: 229.4

ZSpharmac: LDAO Supplier

Product Name: LDAO
CAS No: 1643-20-5
Purity: 99%

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Basic Info

Product Name:LDAO
Other Names:N-Dodecyl-N,N-Dimethylamine-N-Oxide
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:A Crystalline Solid
EINECS No.:216-700-6
Provide:LDAO MSDS;

What is LDAO?

Amine oxide surfactants have superb homes, and also have the homes of both cationic as well as nonionic surfactants. In the 1960s, the extremely reduced toxicity of amine oxide, the soft qualities as well as moisturizing result on the skin, and also the superb homes of sterilization as well as mold resistance drew in people’s attention and also began to be made use of. With the advancement of scientific research as well as modern technology, the research study work of amine oxide has made terrific progression. At present, amine oxide surfactants have actually formed a series of products, among which LDAO is easy to manufacture as well as has the biggest dosage.

LDAO Property

Melting point 132-133 °C(lit.)
Boiling point 371.32°C (rough estimate)
density 0.996 g/mL at 20 °C
vapor pressure 0Pa at 25℃
refractive index n20/D 1.378
Fp 113°C (closed cup)(235
storage temp. -20°C
solubility Ethanol:15.0(Max Conc. mg/mL);65.38(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);1.31(Max Conc. mM)
DMSO:0.1(Max Conc. mg/mL);0.44(Max Conc. mM)
PBS (pH 7.2):0.1(Max Conc. mg/mL);0.44(Max Conc. mM)
form A crystalline solid
Specific Gravity0.97
Water Solubility Insoluble in water.



It is mainly used in shampoo to make the hair softer and easier to comb, with fantastic foam as well as also gloss. Lauryl dimethyl amine oxide can furthermore be utilized on tough surface areas such as tableware, commodes, and also framework outside wall surfaces. Lauryl amine oxide is thoroughly used in daily chemical industry and also fabric printing along with coloring accessories market. It has extraordinary properties such as solubilization, enlarging, emulsification, lathering, foam stabilization, soft top qualities, hydrating, antistatic, non-irritating to the skin, minimized physical poisoning and likewise very easy biodegradation, in addition to additionally has anti-mildew result. Its emulsifying capacity is much better than K-12, as well as additionally its frothing as well as foam supporting capability much exceeds 6501.

The foam created by LDAO is abundant, fragile as well as velvety, specifically suitable for producing baby hair shampoo, and also can make hair glossy, soft, smooth as well as very simple to clean.

LDAO has exceptional emulsifying power for oil spots, along with is most suitable for preparing dishwashing detergents. Cosmetics developed with lauryl dimethyl amine oxide’s emulsifying, moisturizing as well as weak oxidizing homes can make the skin moist, smooth as well as additionally reasonable.

LDAO is used in oral items to create tooth paste, chewing gum, and so on.

LDAO is generally made use of as conditioner, antistatic rep as well as additionally solubilizer in fabric as well as printing and likewise tinting markets. Thickens, minimizes irritability as well as synergizes products.

Application of LDAO

(1) Application in the cosmetics industry
After LDAO is compounded with other surfactants, it can prevent these active substances from easily causing skin roughness, so it is suitable for products that are in contact with the skin. In the shampoo, using a certain amount of amine oxide as a conditioning agent can make the shampoo transparent at pH 4~7, and the conditioning effect is obvious, making the hair soft, smooth, eliminate static electricity, and make the hair black and shiny.

(2) Application of LDAO in printing and dyeing industry
Cotton and cotton blended gray fabrics contain impurities such as cotton shells, colloids, waxes, and oils. In order to improve the dyeing effect, alkali scouring is added to remove the above substances. The scouring agent compounded with lauryl dimethyl amine oxide and non-ionic monophosphoric acid has the advantages of high temperature resistance and strong alkali, and the wetting power and penetration force at high temperature are better than non-ionic, and the scouring gray fabric has high wool efficiency , Uniform and soft, white, high dyeing rate, can save dyes.

When printing and dyeing. Washing off the floating color with a detergent is called soaping. In the early days, soap was used for washing. Now detergents are basically used. Surfactants such as sodium alkylbenzenesulfonate and sodium alkylsulfonate are commonly used. detergent. LDAO not only has strong washing power, but also has the functions of bleaching, softness, antistatic, and sterilization. The detergent produced with dodecyl dimethyl amine oxide and other active agents and auxiliary agents is very suitable for soaping.

Preparation of LDAO

(1) Air oxidation method

The tertiary amine is oxidized with air under high pressure and temperature to obtain dodecyl dimethyl amine oxide. The minimum reaction temperature is 80C, and the reaction pressure must be above 50pa. The catalyst generally uses K.Mo(CN)s, K, Mo:(CN), Fe(22*-bipyridine).

(2) Hydrogen peroxide oxidation method

The tertiary amine is dissolved in water, and under the action of a catalyst, it is oxidized with hydrogen peroxide to obtain dodecyl dimethyl amine oxide, which is a common industrial production method. This method is simple in process and requires less equipment, but hydrogen peroxide is expensive.

Commonly used catalysts mainly include amine carboxyl complexing agents such as ethylenediaminetetraacetate, hydroxyethylethylenediaminetriacetate, diethylenetriaminepentaacetate, etc. Commonly used organic acids are tartaric acid and citric acid, and a mixture of the two is often used in production. The quality of tertiary amines also affects the final product. If the content of primary and secondary amines in tertiary amines is high, the content of free amines in the finished product will increase. Generally, the content of free amines in products should be controlled below 1.5%.

LDAO Performance

(1) Solubility

Soluble in water, ethanol, polyol, acetone and other strong polar solvents,

Insoluble in petroleum ether, kerosene and other non-polar solvents.

(2) Surface tension and penetration:

The surface tension of dodecyl dimethyl amine oxide is very low. At 25C, 0.1% aqueous solution of amine oxide, the measured surface tension is 31.0 dynes/cm. Using the Canvasdisc method, at 25C. 0.1% amine oxide Aqueous solution penetration is 27 seconds.

(3) Foaming power and foam stability

Lauryl dimethyl amine oxide has a strong foaming power, which is stronger in acidic solution than in alkaline solution. At 50C, when the concentration is 0mmol/1, the height measured by the Roche instrument is: 188mm at the beginning and 161mm after 5 minutes. Its foam stabilizing effect is about five times that of coconut fatty acid diethanolamide.

Table 1 is the foam height (mm) measured by the Roche method after adding lauryl alcohol sulfate to two kinds of foam stabilizers respectively.

(4) Thickening

When compounded with amine oxide and other surfactants, it has a thickening effect, and its performance is better than that of alkanolamide, and the thickening effect is more ideal in acidic solution. Shampoo compounded with amine oxide, under acidic conditions, the viscosity increases faster More, the amount of salt is reduced.

(5) Detergency

When amine oxide is compounded with nonionic surfactant, the critical micelle concentration is reduced and the detergency of the compound is improved. Based on imported AEO-9 15% and sodium tripolyphosphate 30% binary compound, AEO-9 (2%, 3%, 4%) is partially replaced with amine oxide, sodium tripolyphosphate remains unchanged, according to the ministry Standard, that is, 250ppm hard water, 0.2% concentration. 45 dead. Wash for 1 hour to compare the detergency. According to QB511-84, the results of detergency are shown in Table 2.

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Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get LDAO Quotation