Zhishang Chemical

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L-Thyroxine CAS 51-48-9

Molecular Formula: C15H11I4NO4

Formula Weight: 776.87

Purity: 99%

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Product Name: L-Thyroxine
CAS No: 51-48-9  

Basic Info

Product Name:L-Thyroxine
Other Names:3,5,3′,5′-TETRAIODO-L-THYRONINE;3,3′,5,5′-TETRAIODO-L-THYRONIN
CAS:51-48-9
Place of Origin:Shandong, China
Brand Name:Zhishang Chemical
Type:Chemical Reagents
Appearance:White crystal
EINECS No.:200-101-1
Storage:Cool Dry Place
Purity:99%
Provide:L-Thyroxine MSDS;
L-Thyroxine COA
Synonyms:

3,5,3’,5’-tetraiodothyronine;beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine;l-3,5,3’,5’-tetraiodothyronine;l-t4;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin;β-((3,5-Diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl)alanine;3,5,3′,5′-TETRAIODO-L-THYRONINE;3,3′,5,5′-TETRAIODO-L-THYRONIN

Product Categories:

API; Medical grade; amino acid; Cell biology; Veterinary grade; Pharmaceutical raw materials; Feed additives; Small molecule inhibitors; Raw materials; Heterocyclic compounds; Pharmaceutical intermediates; Hormones; Biochemical reagents; Biochemicals; Small molecule inhibitors, natural products; Pyridines, fluorine chemistry; Amino acids; Endocrine and hormone; chemical compound; Chemical Reagents; Reference substance; Other biochemical reagents; Prostaglandin series; Organic intermediates; other; Traditional Chinese medicine reference substance; Chemical raw materials; AminoAcids; Organics; HeterocyclicCompounds; AminoAcids&Derivatives; Intermediates&FineChemicals; Pharmaceuticals; IsotopeLabeledCompounds; Aromatics; IsotopeLabelledCompounds; SYNTHROID; Isolabel; OtherAPIs; Inhibitors; Main products; Chemical Reagents

Description:

Amrinone is also known as indanone and is a pyridine phosphodiesterase 3 inhibitor when inoculated. This is a drug that can improve the prognosis of patients with congestive heart failure. Amrinone has been shown to increase heart-induced contraction through high calcium-induced calcium release (CICR). The positive inotropic effect of amrinone is mediated by the selective enhancement of high-gain CICR. The highly selective CICR contributes to the contraction of cardiomyocytes through the phosphorylation of cAMP-dependent protein kinase A (PKA) and Ca. 2+ Calcium Regulatory protein kinase pathway.

Chemical Properties:
Melting point 235 °C
alpha -5 º (1N NaOH:EtOH 1:2)
density 2.4440 (estimate)
Fp 9℃
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Dissolves in 4M ammonium hydroxide in Methanol at 50mg/ml
pka2.2(at 25℃)
form Powder
Boiling point 576.3±50.0 °C(Predicted)
color White to Pale Brown
Water Solubility insoluble
Sensitive Light Sensitive
Merck 9491
BRN 2228515

 

Application:

One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroi d hormone, but has been used to treat hyperlipidemia

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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