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L-Serine Supplement CAS 56-45-1

Molecular Formula: C3H7NO3

Formula Weight: 105.09

ZSpharmac: L-Serine Supplement Supplier

Product Name: L-Serine Supplement
CAS No: 56-45-1
Purity: 99%

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Basic Info

Product Name:L-Serine Supplement
Other Names:L-Serine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:200-274-3
Provide:L-Serine Supplementa MSDS;
L-Serine Supplement COA

What is L-Serine Supplement?

L-serine is a non-essential amino acid with a chemical formula of C3H7NO3 and a molecular weight of 105.09 g/mol. It plays a variety of important roles in chemistry and biochemistry, especially in protein synthesis and metabolism in organisms.

L-serine is an α-amino acid with a hydroxyl (-OH) side chain, which makes it hydrophilic. At physiological pH, L-serine is neutral because the dissociation of its carboxylic acid group and amino group is roughly equal. Its side chain is small and relatively simple, which affects its role in the tertiary structure of proteins.

L-serine can be synthesized in organisms through a variety of pathways, the most common of which is from glycine or 3-phosphoglycerol, through transamination or dehydration synthesis pathways. It is also a key intermediate in the purine nucleotide synthesis pathway. In addition, L-serine can be converted into pyruvate through deamination, and then participate in carbohydrate and energy metabolism.

L-Serine Supplement Property

Melting point 222 °C (dec.) (lit.)
alpha 15.2 º (c=10, 2N HCl)
Boiling point 197.09°C (rough estimate)
density 1.6
refractive index 1.4368 (estimate)
Fp 150°C
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form powder
pka2.19(at 25℃)
color White
PH5-6 (100g/l, H2O, 20℃)
Odorwh. cryst. or cryst. powd., odorless, sweet taste
optical activity[α]20/D +13.5±0.5°, c = 5% in 5 M HCl
Water Solubility 250 g/L (20 ºC)


Application of L-Serine Supplement

1. Medical field
Nutritional supplementation and treatment: L-Serine Supplement is often used in nutritional supplements, especially for patients with specific diseases or metabolic disorders, such as patients with serine deficiency, to help supplement essential amino acids in the body and promote health.
Drug synthesis: As a starting material or intermediate for chemical synthesis, L-Serine Supplement is involved in the construction of a variety of drug molecules, including some drugs for the treatment of liver diseases, nervous system diseases and genetic diseases.
Biopharmaceuticals: In the process of biopharmaceuticals, L-serine, as a component of the culture medium, plays an important role in promoting cell growth and protein expression. It is an indispensable nutrient for the production of recombinant proteins, vaccines and other biological products.

2. Food industry
Nutritional fortification: As a food additive, L-Serine Supplement can increase the nutritional value of food, especially in infant formula, special medical foods and nutritional supplements for athletes, to balance the ratio of amino acids and improve protein quality.
Food processing: In some processed foods, L-serine can be used as a stabilizer or taste improver to improve the texture and taste of food.

3. Cosmetics Industry
Skin moisturizing and repair: L-Serine Supplement is widely used in skin care products due to its good moisturizing properties. It can help maintain the moisture balance of the skin and promote the repair of the skin barrier. It is suitable for dry and sensitive skin.
Anti-aging products: As an ingredient in anti-aging cosmetics, L-serine can participate in the synthesis of collagen, help reduce fine lines and wrinkles, improve skin elasticity, and fight signs of aging.

4. Biotechnology and research
Protein expression: In biotechnology laboratories, L-serine is a regular component of cell culture medium, which can optimize the cell growth environment and promote the efficient expression of target proteins.
Scientific research tools: As an important reagent in biochemistry and molecular biology research, L-serine and its derivatives are used to study protein structure, enzyme activity and metabolic pathways, providing basic materials for the advancement of life sciences.

5. Agriculture and feed
Animal nutrition: Adding L-serine to animal feed can optimize the growth performance of animals and improve the yield and quality of meat, dairy products, etc., especially in high-yielding dairy cows and fast-growing poultry feed.

L-Serine Supplement Prominent Applications in Cosmetics

1. Moisturizing and water-locking function
L-Serine Supplement contains a hydrophilic hydroxyl (-OH) group, which enables it to attract and retain moisture and enhance the skin’s hydration capacity. In cosmetic formulas, L-serine, as a component of the natural moisturizing factor (NMF), can help maintain the moisture balance of the stratum corneum and reduce water evaporation, thereby improving dry and rough skin conditions and keeping the skin soft and smooth.

2. Promote skin barrier repair
The soundness of the skin barrier function is essential for maintaining skin health. L-Serine Supplement is involved in the biosynthesis of phospholipids and sphingolipids, which are key components of the skin barrier. By promoting the production of these lipids, L-serine helps strengthen the skin barrier and reduce the damage of external irritation and pollutants. It is particularly beneficial for the repair of sensitive skin and damaged skin.

3. Anti-aging effect
L-Serine Supplement plays an important role in cell metabolism and can promote the synthesis of collagen and elastin, two proteins that are key to maintaining skin elasticity and firmness. Therefore, it is widely used in anti-aging products to help reduce the appearance of fine lines and wrinkles, improve skin elasticity and radiance, and fight signs of aging.

4. Mildness and compatibility
Since L-serine is one of the amino acids naturally present in the human body, it has good biocompatibility and low irritation, making it suitable for all skin types, including sensitive skin. In cosmetic formulas, L-serine has good compatibility with other active ingredients and can work synergistically to enhance the effectiveness of the overall formula.


National Center for Biotechnology Information. “PubChem Compound Summary for CID 5951, Serine” PubChemhttps://pubchem.ncbi.nlm.nih.gov/compound/Serine. Accessed 21 June, 2024.

As a company specializing in the production and supply of L-Serine Supplement raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the L-Serine Supplement raw materials you need to support your production and research and development.

We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.

If you have any needs or are interested in our products, please contact our service staff directly, and we will wholeheartedly provide you with the best service and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get L-Serine Supplement Quotation