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L-Leucine Powder CAS 61-90-5

Molecular Formula: 61-90-5

Formula Weight: 131.17

ZSpharmac: L-Leucine Powder Supplier

Product Name: L-Leucine Powder
CAS No: 61-90-5
Purity: 99%

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Basic Info

Product Name:L-Leucine Powder
Other Names:L-Leucine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Off-White Powder
EINECS No.:200-522-0
Provide:L-Leucine Powder MSDS;
L-Leucine Powder COA

What is L-Leucine Powder?

L-Leucine, full name L-α-aminocaproic acid, is an essential amino acid and one of the basic building blocks of protein. In terms of chemical structure, it has a chiral center and exists in two stereoisomers, of which L-Leucine is a naturally occurring and biologically active form. The chemical formula is C6H13NO2, and the molecular weight is 131.17 g/mol. L-Leucine cannot be synthesized by itself in the body and must be ingested through diet. It is essential for maintaining life activities, especially in the synthesis and repair of muscle protein, energy metabolism, and immune function.

L-Leucine Powder Property

Melting point 

>300 °C (lit.)


15.4 º (c=4, 6N HCl)

Boiling point 

122-134 °C(Press: 2-3 Torr)


1,293 g/cm3

vapor pressure 

<1 hPa (20 °C)

refractive index 

1.4630 (estimate)



storage temp. 



1 M HCl: 50 mg/mL




2.328(at 25℃)


White to Off-white


at 100.00?%. odorless


5.5-6.5 (20g/l, H2O, 20℃)

optical activity

[α]20/D +15.5°, c = 2 in 6 M HCl

Water Solubility 

22.4 g/L (20 C)


L-Leucine Powder Uses

1. Nutritional supplements and sports science
Muscle growth and recovery: L-Leucine Powder is a key amino acid that promotes muscle protein synthesis, accelerates muscle recovery after training, and reduces muscle damage. Therefore, it is widely used in nutritional supplements for fitness and athletes, such as protein powder, branched-chain amino acid (BCAA) supplements, etc.
Energy metabolism: During high-intensity exercise or hunger, L-leucine can be converted into glucose through the gluconeogenesis process to provide energy support and maintain blood sugar levels and exercise performance.

2. Medical nutritional therapy
Patient rehabilitation: In hospital nutritional therapy, L-Leucine Powder is used to enhance nutritional support for patients with low immunity, postoperative recovery, severe burns or trauma, promote tissue repair and reduce muscle loss.
Chronic disease management: For patients with chronic diseases such as diabetes and liver disease, supplementing L-leucine helps regulate protein metabolism, improve body composition, and support disease management.

3. Food industry
Food fortification: As a food additive, L-Leucine Powder is used to improve the nutritional value of specific foods, such as infant formula, special medical foods, etc., to meet the additional needs of specific populations for essential amino acids.
Taste improvement: L-leucine and its derivatives are also used for food seasoning, improving the taste and flavor of food by enhancing the umami taste.

4. Animal Husbandry and Breeding
Feed additives: Adding L-leucine to animal feed can optimize the growth performance of animals and improve the yield and quality of products such as meat, eggs, and milk, especially for monogastric animals such as pigs and chickens, where L-leucine is one of the limiting amino acids.

5. Biotechnology and Pharmaceuticals
Protein synthesis: In the field of biopharmaceuticals, L-Leucine Powder is an important raw material for the synthesis of specific proteins and peptide drugs, and is used to produce vaccines, antibody drugs, etc.
Cell culture: As a component of cell culture medium, L-leucine supports cell growth and proliferation, which is essential for biological research and the production of biological products.

6. Cosmetics and Personal Care
Skin care: Although not as common as other fields, some derivatives of L-Leucine Powder have begun to appear in high-end skin care products due to their moisturizing and antioxidant properties, aiming to promote skin health.

L-Leucine Powder Prominent Applications in Cosmetics

1. Promote skin repair and regeneration
As one of the essential amino acids for protein synthesis, L-Leucine Powder can promote the regeneration and repair process of skin cells. In some anti-aging or trauma repair skin care products, adding L-leucine can help accelerate the recovery of damaged skin, improve skin texture, reduce scar formation, and thus improve the overall health of the skin.

2. Moisturizing and barrier function enhancement
Although L-Leucine Powder itself is not a typical moisturizing ingredient, it indirectly helps maintain the water-oil balance and barrier function of the skin by promoting the health of the skin. A healthy skin barrier can lock in moisture more effectively and reduce water loss, thereby achieving a moisturizing effect.

3. Antioxidant and anti-inflammatory effects
The metabolic process in which L-Leucine Powder participates can promote the production of antioxidant substances in the body, indirectly combating skin aging caused by free radicals.

4. Cell communication and signal transduction
At the cellular level, L-Leucine Powder participates in regulating multiple cell signal transduction pathways, including signaling pathways related to mTOR (mammalian target of rapamycin), which is essential for controlling cell growth, differentiation, and metabolism. In high-end anti-aging skin care products, L-leucine may be used as a co-ingredient to activate these pathways to promote skin rejuvenation and elasticity.

5. Management of specific skin problems
Although there is less direct evidence, in theory, the use of L-leucine may be beneficial for certain specific skin problems (such as acne) by regulating skin oil secretion, reducing inflammatory responses, and helping to maintain a clean and healthy skin state.


National Center for Biotechnology Information. PubChem Compound Summary for CID 6106, Leucine. https://pubchem.ncbi.nlm.nih.gov/compound/Leucine. Accessed June 21, 2024.

As a company specializing in the production and supply of L-Leucine Powder raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure the quality and stable supply of our products. No matter where you are, we can provide you with the L-Leucine Powder raw materials you need to support your production and research and development.

We always adhere to the principle of honest management, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relations with domestic and foreign customers and won their trust and praise.

If you have any needs or are interested in our products, please contact our service staff directly, and we will wholeheartedly provide you with the best service and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get L-Leucine Powder Quotation