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L-Cysteine Monohydrochloride CAS 52-89-1

Molecular Formula: C3H8ClNO2S

Formula Weight: 157.62

ZSpharmac: L-Cysteine Monohydrochloride Supplier

Product Name: L-Cysteine Monohydrochloride
CAS No: 52-89-1
Purity: 99%

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Basic Info

Product Name:L-Cysteine Monohydrochloride
Other Names:L-Cysteinehydrochloride
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Light Brown Solid
EINECS No.:200-157-7
Storage:Room Temperature
Provide:L-Cysteine Monohydrochloride MSDS;
L-Cysteine Monohydrochloride COA

What is L-Cysteine Monohydrochloride?

L-cysteine hydrochloride (L-CysteineHyolrochloride) is a vital organic chemical intermediate, which has a selection of uses in biochemistry and biology, medicine, food, feed as well as likewise cosmetics, as well as the demand in your house as well as additionally abroad is boosting year by year. It is generated when it is transformed right into L-cysteine under the activity of hydrochloric acid. It is an anemic crystal with a melting point of 175-179 ° C. It breaks down when it reaches the melting point. It has details hygroscopicity and also gradually oxidizes in the air. It is soluble in water, ethanol, acetone, antarctic acetic acid and also ammonia water, and so on, and likewise insoluble in organic solvents such as ether, benzene, carbon disulfide as well as likewise chloroform. Strategies for L-cysteine synthesis consist of electrolytic decline, chemical synthesis, and also chemical methods. Amongst them, the chemical synthesis technique has really been taken on due to its high conversion price.

L-Cysteine Monohydrochloride Property

Melting point 180°C
alpha 5.5 º (c=8, 6 N HCL)
storage temp. Inert atmosphere,Room Temperature
solubility H2O: 1 M at 20 °C, clear, colorless
form Solid
color White to light brown
optical activity[α]20/D +6.4±0.3°, c = 5% in 5 M HCl
Water Solubility SOLUBLE


Applications of L-Cysteine Monohydrochloride

1. Biomedicine
L-Cysteine Monohydrochloride is an essential sulfur-containing amino acid that can synthesize reduced glutathione, which is among the components of glutathione. This is a crucial material related to the redox system in the living body. This product has been utilized in clinical cosmetics for the therapy of allergic diseases, facial cancer malignancy, sweat places, and pigmentation of numerous causes; it can additionally advertise the recovery of different corneal damage illness. Since the L-cysteine particle includes energetic sulfhydryl groups, it has lots of crucial physiological functions: such as boosting liver feature, removing benzene poisoning, reducing phlegm, advertising hair development and protecting against food oxidation, etc. It is widely made use of in medication, food, cosmetics as well as feed industries. According to the physical feature of L-Cysteine Monohydrochloride in the human body as well as its chemical residential or commercial properties, it can be made right into a variety of L-cysteine medicines with wide applications, such as antitussive, expectorant, anti-inflammatory, antipyretic, cancer cells therapy and also anti-bacterial and cancer cells cell growth and also various other medicines. L-cysteine medicines can also be straight used to treat leukopenia, poisoning, liver disease, and stop as well as treat radiation damage to the body. L-cysteine hydrochloride shot has the effect of promoting liver feature, and also is used to treat hepatitis, serum sickness, antimony and other drug poisoning, and also can avoid and also treat radiation damage.

2. Bio-cosmetics
L-Cysteine Monohydrochloride has the feature of preventing the aging of microorganisms. Since L-cysteine has numerous physical features, free L-cysteine has actually been made into substances (such as salts, esters, acylates, etc) of not natural acids and organic acids. L-cysteine has the effects of sun security, expectoration, prevention and therapy of radiation damage to the body, so it has a wide variety of uses. In medication, cysteine can be used in the therapy of hepatitis and also antimony poisoning. A lot more importantly, cysteine has anti-radiation ability and also can be made use of in the avoidance as well as therapy of contaminated conditions and cosmetics. In addition to being generally dispersed in the liver, spleen and kidney, L-Cysteine Monohydrochloride likewise collects in large amounts on the surface of the body (consisting of the skin, mucous membranes, as well as the surface of the gastrointestinal system, etc). L-cysteine can boost hair development and also is utilized for alopecia individuals.

3. Food
Nourishing as well as scrumptious foods contain protein and totally free amino acids, which are the major spices of food flavor. In the food market, L-Cysteine Monohydrochloride can be heated up together with six-carbon sugar or five-carbon sugar to produce a meat-like fragrance, and also it can be decayed and also mixed with veggie healthy protein to make fabricated meat essence. Adding L-cysteine to corn refined products can raise the fragrance of corn by 10 to 40 times. L-Cysteine Monohydrochloride sustains the development of children. When young children consume L-cysteine food for a long time, they can make their hair black as well as glossy. L-cysteine is made use of in meat products, dairy products, bread, as well as flour sugar products, which can boost food security and reduce fermentation blackening reaction; the stabilizing impact of ascorbic acid has a fantastic opportunity to slow down the automated oxidation of fat, enhance the result of food preservatives, and also have a fantastic effect on the fragrance of food. Utilized in all-natural fruit juices to prevent the oxidation of vitamin C and also prevent the fruit juices from turning brownish, which can lengthen the life span of natural fruit juices. It is commonly made use of in milk powder in Japan to avoid the milk powder from going bad. Adding L-cysteine to all-natural fruit juices as an anti-oxidant works in protecting against food wasting.

Production Method of L-Cysteine Monohydrochloride

Approach 1. Hydrolysis-electrolysis
Pig hair as well as hair are used as basic materials to different cystine through hydrolysis and adjust the isoelectric variable of cystine, and also after that electrolytically minimize cystine to obtain cysteine.
Cystine is hydrolyzed
Pig hair, hair [HCl, 117 ° C, 7h] → [acid hydrolysis] hydrolyzate [NaOH, pH4.8] → [neutralization] L-cystine (raw product).
Electrolytic decrease remains in 2 different pool, one swimming pool is loaded with 1mol/L HCl as well as likewise put right into the ink stick, attached to the positive pole of the power supply, this pool is the anode, as well as the various other swimming pool contains cystine hydrochloric acid treatment (cystine: Concentrated HCl: water = 1:1:4), placed right into the lead plate, connected to the negative pole of the power supply, this swimming pool is the cathode. Consist of a salt bridge connection in between both swimming pools. Activate the power supply and adjust the present to 5A to perform electrolysis, along with the electrolysis is completed in concerning 6-7 hrs. Take a little electrolyte solution as well as likewise include pyridine dropwise, no turbidity suggests that the electrolysis is full.
L-cystine [HCl] → [electrolytic decline] L-cysteine hydrochloride [decolorization, concentration, condensation] → development of L-cysteine hydrochloride.
After decolorization, concentration, in addition to condensation electrolysis are finished, got rid of the power supply, consist of 10g/L (1%) triggered carbon according to the feeding amount, heat to 70 ° C, as well as preserve warm for half a hr. Filter to obtain the filtrate. Concentrate under decreased stress up until there are crystals, stir to entirely speed up the crystals, gather the crystals by filtering, clean with 95% ethanol, in addition to entirely dry in vacuum cleaner listed below 60 ° C to obtain L-cysteine hydrochloride without crystal water.
Technique 2, enzymatic method.
DL-2-aminodihydrothiazoline-4-carboxylic acid (DL-ATC) chemical hydrolysis strategy.

Dosage of L-Cysteine Monohydrochloride

L-Cysteine Monohydrochloride can be used as flour therapy agent and nutritional supplement. As a nutritional supplement, its included amount ought to not go beyond 2.3% of the total healthy protein content (consisting of L-cystine). my country’s “Hygienic Standards for making use of Food Additives” (GB2760-1996) states: for fermented flour items, 0.06 g/kg.

Recommendation dosage: It can be added to the flour and mixed evenly during details use, or included when kneading the dough. Typically, the dose for bread is 0.02 ~ 0.045 g/kg; for natural fruit juice, it can avoid the oxidation and also browning of vitamin C, and also the dosage is 0.2 ~ 0.8 g/kg.

About Products:
If you need L-Cysteine Monohydrochloride as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced L-Cysteine Monohydrochloride manufacturer and supplier, ZSpharmac will provide L-Cysteine Monohydrochloride raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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