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L-Citrulline CAS 372-75-8

Molecular Formula: C6H13N3O3

Formula Weight: 175.19

ZSpharmac: L-Citrulline Supplier

Product Name: L-Citrulline
CAS No: 372-75-8
Purity: 99%

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Basic Info

Product Name:L-Citrulline
Other Names:L(+)-Citrulline
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystals or Crystalline Powder
EINECS No.:206-759-6
Storage:Room Temperature
Provide:L-Citrulline MSDS;
L-Citrulline COA

What is L-Citrulline?

L-citrulline is what we call a non-essential amino acid. Not important due to the fact that the body can produce this amino acid on its own. However, we can increase the degrees of L-citrulline in our body by consuming foods or supplements that contain L-citrulline.

Compared to most various other amino acids, L-citrulline is a non-protein amino acid, indicating it is not involved in structure proteins. Initially found and also separated from watermelon juice, it stays an outstanding all-natural source of L-citrulline to this particular day.

L-Citrulline Property

Melting point 214 °C
alpha 25.5 º (c=8, 6N HCl)
Boiling point 306.48°C (rough estimate)
density 1.2919 (rough estimate)
refractive index 26 ° (C=8, 6mol/L HCl)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Aqueous Acid (Sparingly). Water (Slightly)
pka2.43(at 25℃)
form Crystals or Crystalline Powder
color White
Water Solubility 200 g/L (20 ºC)


The Efficacy And Role of L-Citrulline

L-Citrulline is a non-protein amino acid that has the capacity to create peptide bonds yet does not take part in healthy protein synthesis. Citrulline was once thought about an intermediate item in the urea cycle. However, current research studies have revealed that citrulline can be widely made use of in medicine, food, health care as well as various other facets, as well as has excellent pharmacological results.
1 Prevention as well as therapy of prostate conditions
L-Citrulline has a considerable result on the prevention and therapy of prostate diseases, including prostatitis, prostate swelling, prostatic hypertrophy, benign prostatic hyperplasia, as well as prostate cancer cells. Wang Jianghai and others invented a technique to raise the web content of citrulline as well as anti-proliferative aspect energetic materials by generating germination of pumpkin seed embryo cells and removing these substances, which can be utilized as clinical basic materials or practical natural food.
2 Boost male sexual feature
L-Citrulline can create the body to generate nitrogen oxides, which are very vital compounds for male sexual performance. Unlike performance-enhancing medications, citrulline can be entirely absorbed right into the blood, making it simpler to produce nitrogen oxides, therefore attaining the impact of penile erection. In addition, as a pure natural item, citrulline not only has no negative effects, yet can also thoroughly enhance the physical problem of guys. It is referred to as Green Viagra, and some companies in the United States have actually created associated items. A technique for removing citrulline from watermelon has been revealed in current patents, which can be made right into tablet computers and also capsules.
3 Anti-aging and boost immunity
Research studies have located that L-Citrulline has strong antioxidant ability, can get rid of hydroxyl teams, boost arginine needed for NO synthesis, and can efficiently secure DNA as well as PMN from oxidation responses. It can be used as a health care for anti-aging and also enhancing immunity It can additionally be made use of as a charm cosmetic for females, and has the results of skin treatment, anti-wrinkle, freckle, and anti-aging. As an example, L citrulline malate is an amino acid salt health product with increasing sales in the worldwide market.It can be squared away into traditional strong preparations, such as tablets, powders, granules, pills, and more, right into liquid preparations, such as water or oily suspensions, or various other liquid preparation job such as syrup, etc. The sugar-free citrulline oral spray along with bubbly tablet computer systems designed by Zhao Li can be well soaked up by all sort of individuals, supplement the nutrients required by the body, hold-up aging along with improve immunity. Some citrulline-based healthcare as well as skin treatment items in European along with American countries have really similarly been kept in mind.

Does L-Citrulline Really Improve Athletic Performance?

L-Citrulline vs. L-Arginine

What is the main difference in between Arginine in addition to Citrulline?
Both arginine and also citrulline are non-essential amino acids that are required for a number of components of health and wellness. Nevertheless, citrulline is in fact changed to arginine, which is utilized to generate nitric oxide, an essential compound that aids maintain far better blood flow by unwinding the muscle mass inside capillary.

As a result of their resemblances, L-citrulline as well as L-arginine with each other dominate in supplements made use of to treat problems like high blood pressure and also impotence. Incredibly, nevertheless, some looks into have really situated that taking citrulline can increase arginine levels much better than taking arginine supplements alone.

In fact, amongst the best differences in between citrulline as well as likewise arginine is just exactly how these 2 amino acids are absorbed in the body. A research launched in “Nourishment” noted that citrulline is taken in particularly well when taken by mouth.

Lots of supplements additionally include these crucial amino acids to assist deal with concerns like high blood pressure in addition to impotence. Nevertheless, a lot more research study is called for to find out optimal L-arginine as well as L-citrulline provides for ED as well as likewise various other conditions, and also whether L-arginine as well as likewise L-citrulline must be taken at going to bed, with a recipe, or at various other times throughout the day. L-citrulline.

About Products:
If you need L-Citrulline as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced L-Citrulline manufacturer and supplier, ZSpharmac will provide L-Citrulline raw materials for customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get L-Citrulline Quotation