Kinetin CAS 525-79-1

Molecular Formula: C10H9N5O

Formula Weight: 215.21

ZSpharmac: Kinetin Raw Material Supplier

Product Name: Kinetin

CAS No: 525-79-1

Purity: 99%

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Basic Info

Product Name:	Kinetin
Other Names:	6-Furfurylaminopurine
CAS:	525-79-1
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	White Crystalline
EINECS No.:	208-382-2
Storage:	-70°C
Provide:	Kinetin MSDS； Kinetin COA

What is Kinetin?

Kinetin, referred to as K or KT kinetin, English name 6-Furfurylamino-purine (Kinetin). Kinetin is an abnormal cytokinin. Chemical name: 6-furfurylaminopurine (or N6-furylmethyladenine, molecular formula C10H9N5O). Insoluble in water, soluble in strong acid, alkali and glacial acetic acid. In addition to advertising cellular division, it also has the influences of postponing senescence of eliminated fallen leaves, generating bud difference and boosting stomatal opening.

Kinetin Property

Melting point	269-271 °C (dec.)(lit.)
Boiling point	355.49°C (rough estimate)
density	1.2639 (rough estimate)
refractive index	1.7610 (estimate)
Fp	269-271°C
storage temp.	-70°C
solubility	H₂O: soluble
form	crystalline
pka	pKa1 2.7; pKa2 9.9(at 25℃)
color	white
Water Solubility	Soluble in water (<1 mg/ml) at 25°C, Acetic acid (49.00-51.00 mg/ml), DMSO (43 mg/ml) at 25°C, ethanol (<1 mg/ml) at 25°C, 0.1 N Sodium hydroxide (1% w/v), methanol (slightly), and dilute aqueous hydrochloric acid or sodium hydroxide (freely).

The Effect of Kinetin on Human Skin

Kinetin is amongst a team of substances called cytokinins, which are plant development regulators. In plants, kinetin promotes cellular division and turns on cell advancement and distinction treatments. It works as an antioxidant, avoiding oxidative damage activated by entirely complimentary radicals.

Although these features of kinetin have been demonstrated in plants, it has actually only been utilized in skin therapy and sophistication products thinking about that 1994. It wasn’t until Valeant Pharmaceuticals’ Kenasa used kinetin and star Courtney Cox (“Pals”) suggested it that it happened noticeable. According to the WrinkleReview.com web site (# 2), kinetin functions as a necessary development hormone that affects cell advancement and differentiation, therefore postponing and combating the indications of aging. Kinetin permits skin to recover itself by splitting to create brand-new cells. In addition to this, its antioxidant domestic or commercial properties secure the outer layer of the skin from complimentary severe damage. Kinetin has really also been disclosed to reduce folds, enhance skin appearance, and reduce the look of pigmented areas.

A February 2002 study from the College of North Carolina at Chapel Hill, launched in the Journal of Dermatology (# 3), located that a 12-week face segmentation contrast research study showed that skin structure, skin color, spread places, and plaques 62% improvement in dark spots and fine lines. Revlon performed a research of 98 people with modest to modest photodamage over 10 weeks and situated that it can substantially enhance skin appearance, complexion, areas and great lines.

New Uses of Kinetin in Plant Growth Regulation

There are extremely couple of existing innovations that change the blossom body organ proportion of plants. For example, Chinese Certificate Publication No. CN101292607A divulges “a technique for controling the blossom body organ proportion of Jatropha curcas with chemical reagents”. Ethephon and gibberellin play the task at the same time. Nonetheless,, it is not exceptional to boost the proportion of male and women blooms of Jatropha curcas. As one of the plants that can develop biodiesel, Jatropha curcas has seeds bountiful in oil, with solid oil fluidness and premium. It has high research value and financial well worth. As a power plant, it is increasingly commonly grown. Its prospective medical worth is additionally constantly being investigated and established in a far more in-depth and well organized fashion.

Jatropha curcas has monoecious flowers and cymes, which impacts the return of Jatropha curcas seeds. A significant think about the decreased fruit-bearing price is that the proportion of guy and women blooms of Jatropha curcas is likewise decreased. For that reason, there is an urgent demand to investigate the kinds and focus of hormonal representatives optimal for enhancing the return of Jatropha curcas, so pertaining to increase the return of Jatropha curcas, aid the growing and producing of Jatropha curcas, far much better exert its extremely own economic worth, and speed up the scientific improvement of the Jatropha curcas market. It provides theoretical and technological suggestions for Jatropha planting places and bases, and boosts the revenues of farmers in rural areas who depend upon Jatropha curcas growing as their key income.

A brand-new production discloses a new use kinetin KT in plant advancement standard, which is to make use of kinetin KT to manage the proportion of blossom organs of Jatropha curcas and boost the proportion of male and women blooms of Jatropha curcas. The focus range of kinetin KT spraying under certain troubles is 1mg/L -5 mg/L. The particular problems referred to are that the plant is more than 2 years of ages. The splashing approach is to spray the trimmings of the Jatropha curcas plant in the blossom bud phase of the extremely initial plant. When splashing, the droplets have to be little and also. The quantity requires to be restricted to moistening the sprayed location and permitting little droplets to stream down. The spraying time needs to be in between 14:30 and 16:30 on a warm day. If it rainfalls within 36 hours after splashing, Re-spray; the spray emphasis of kinetin KT is 3mg/L. The development attends to the problem of reduced percentage of males and female flowers of Jatropha curcas. The development can enhance the ratio of man and women blossoms of Jatropha curcas by 14.80% to 36.18%, efficiently increasing the return of a singular Jatropha curcas plant and obtaining the objective of raising yield.

Synthesis Method of Kinetin

Currently, the main synthesis methods of 6-furfuryl aminopurine contain: condensation of adenine and furfuryl chloride under the activity of antacids; condensation of methylthiopurine and furfurylamine; condensation of adenine and furfurylamine; condensation of acylpurine and furoyl chloride to create furoylpurine. After that it is gotten by decline of lithium light weight aluminum hydride; condensation of adenine and furfuryl alcohol, and so forth. However, these approaches have troubles such as limited resources of basic materials or reduced returns. The reaction method of 6-chloropurine and furfurylamine is added straight, due to the fact that the chlorine at the 6-position is exceptionally active., it has actually been reported in the literary works that feedback in ethanol or butanol solvents can easily generate spin-offs in which chlorine is altered by alcohol, resulting in single-hybrid failure.

WO2020048343A1 discloses a method for making high-purity 6-furfurylaminopurine, which is identified by including the following actions: reacting furfurylamine and 6-chloropurine in hexamethyldisilazane in the presence of DBU to acquire 6- Raw furfuryl aminopurine is recrystallized to acquire high purity 6-furfuryl aminopurine, with HPLC purity of above 99.5% and single contaminations less than 0.1%.

Additionally, in the above technological service, the response is preferably executed by blending furfurylamine and DBU, raising the temperature of 6-chloropurine and hexamethyldisilazane to 110-115 ° C, and starting to drop the mix of furfurylamine and DBU.

Much more, in the above technological treatment, the molar percentage of 6-chloropurine to furfurylamine is 1:1 -1.15.

Much more, in the above technological option, the molar proportion of 6-chloropurine to DBU is 1:1 -1.2.

Furthermore, in the above technical service, the feedback temperature degree is 110-130 ° C.

Furthermore, in the above technical remedy, the recrystallization solvent is ethanol.

This technique has easy procedure, high yield and no drainage discharge.

About Products:
If you need Kinetin, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
Our company, as an experienced Kinetin manufacturer and supplier, ZSpharmac will provide Kinetin raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.