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Isocyclocitral CAS 1335-66-6

Molecular Formula: C20H32O2

Formula Weight: 304.47

ZSpharmac: Isocyclocitral Supplier 

Product Name: Isocyclocitral
CAS No: 1335-66-6
Purity: 99%

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Basic Info

Product Name:Isocyclocitral
Other Names:Isocyclic citral
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless to Yellow Liquid
EINECS No.:215-638-7
Provide:Isocyclocitral MSDS;
Isocyclocitral COA

What is Isocyclocitral?

Isocyclocitral is a mix of 2 isomers of 2,3,5 (or 2,4,6)-trimethyl-4 (or 3)cyclohexen-1-al. An anemic liquid with a citrus and verbena-like soil-green fragrance. A colorless fluid with a strong, fresh environment-friendly aroma, accompanied by citrus and verbena-like notes. It is a blend of isomers, among which isomer (I), likewise called 2,4,6-trimethyl-3-cyclohexenyl formaldehyde; isomer (II), likewise referred to as 3,5, 6-Trimethyl-3-cyclohexenylcarbaldehyde. Insoluble in water, soluble in organic solvents such as ethanol.

By 2-methyl-1,3-pentadiene and also crotonaldehyde took place in the diene synthesis reaction in the system. Made use of as a seasoning. Mixing this product with oakmoss spices can improve the fragrance of the leading scent. Mixing with ionones can create a fresh fragrance. Blending with aromatic fallen leaves and gerbils can boost the eco-friendly and also vegetable fragrance.

Isocyclocitral Property

Odorat 100.00 %. green aldehydic earthy woody herbal leaf
Odor Typegreen


Isocyclocitral Application

Isocyclocitral can be utilized in flower scent formulas to impart a fresh and also all-natural fragrance. Proper quantity is used in the formula of fragrance and also flavor, and also good result can be acquired. It can be used for hyacinth, sweet bean curd, xiangwei and also other types. It can likewise be utilized to include fragrance to household cleansers, or to cover up poor smell in industry. The dose can reach 10%. Its application instances are as adheres to:

1. Prepare a pharmaceutical make-up for treating atherosclerosis;
The pharmaceutical structure is prepared from the adhering to raw materials: perillaldehyde, veratraldehyde, and also Isocyclocitral; it can dramatically prevent the boost of blood lipids in rats fed a high-fat diet plan, and also can properly treat atherosclerosis with obvious impacts as well as steady quality control. It appropriates for individuals Advantages of lasting use. Defined perillaldehyde, veratraldehyde, isocyclic citral can straight obtain by commercially readily available, also can obtain by plant extraction. In the present invention, the above resources are pulverized as well as sieved according to components by weight, combined, packed into pills or compressed right into tablet computers; or combined with pharmaceutically appropriate carriers or diluents, then filled up into capsules or compressed right into tablets.

2. prepare a type of oil-based ink with lemon significance,
Made up of lemon flavor, maltodextrin as well as sodium starch octenyl succinate, lemon taste with triethyl citrate, methyl dihydrojasmonate, peach aldehyde, ethyl naphthalene ethyl ether, dodecyl nitrile, ethyl ionone, G-decalactone, fenopai, allyl cyclohexyl propionate, tricyclodecenyl acetate, methyl-turkone, vanillyl acetate, neryl acetate, undecanal, dodecanal, formic acid scent Pectinate, Geranyl Formate, Geraniol, Citronellol, Nerol, Citral, Capric Aldehyde, Styroyl Acetate, Oil of Lemon Eucalyptus, Isocyclic Citral, Ligular, Dihydromyrcenol, Linalool, Allyl Caproate, Ethyl Dimethyl Butyrate, Terpinolene, Brasilian Orange Oil, Limonene Terpene, Octanal, Paracymene, Tangerine, Vanillin, Grapefruit Oil, Glyceryl triacetate make-up. Likewise given is a preparation technique of the above-mentioned lemon essence for oil-based ink, which boosts the fragrance retention effect as well as oil solubility of the essence.

3. For the preparation of an enhanced healthy latex paint,
It is made of the following raw materials in parts by weight: 3.5-5.6 parts of salt tetrametaphosphate, 20-25 parts of white latex, 10-14 parts of titanium dioxide, 5-9 parts of kaolin, 2.5-3.6 parts of Isocyclocitral, triphenylethyl 1.5-4.5 parts of phenol polyoxyethylene ether, 1.2-2.6 parts of polyoxyethylene lauryl ether, 2.5-3.5 parts of nitrocellulose film-forming agent, 1.6-3.8 parts of ethylene-vinyl acetate copolymer, as well as 6.2-7.6 parts of water. Compared to the existing latex paint, the here and now invention has smooth and also smooth finish movie, delicate appearance, silk gloss, high hiding power, solid adhesion, exceptional antibacterial and also mildew resistance, outstanding water as well as alkali resistance, and the layer film can be washed., durable luster, the innovation appropriates for indoor interior walls, has reduced manufacturing price as well as lower toxicity, and also is suitable for popularization as well as use.

A natural phosphine pharmaceutical intermediate, which is prepared from the following resources in parts by weight: 2-7 parts of isocyclic citral, 20-35 parts of diphenylproline silyl ester, ethyl pandan 3-9 parts of prime, 1-5 parts of surfactant, 1-5 parts of complexing agent, 5-10 parts of phosphorus trihalide, 5-10 parts of methylphosphoric acid, and 3-9 parts of driver. Those latex paint is green and environmentally friendly, has easily available raw materials, is easy to industrialize production, has no side effects, can properly deal with conditions, and also can additionally be made use of as a crucial energy source in the body.

4. For the manufacture of an absorbing article,
The absorptive short article comprises several complexing or encapsulating compounds picked from the team containing melonal, haddock aldehyde, trans-2-hexenal, Ligustaldehyde, Floral-Super, Floral, 5-methyl-2-thiophene-formaldehyde, Solanal, Undecenal, 9-Undecenal, 10-Undecenal, Trans-4 -decenal, cis-6-nonenal, isocyclic citral, methyl citral b, (E)-2, (z)-6-nonadienal, undecanal, methyl- Octyl-acetaldehyde, laurylaldehyde, silvial, vanillin, 2,2-dimethyl-(3-p-phenylethyl)propanal; claimed absorbent write-ups are specifically reliable in lowering malodor from destruction of proteinaceous substances, The proteinaceous material is such as food, menses or feces.

Isocyclocitral Preparation

The preparation method of isoisocyclic citral is as follows: crotonaldehyde and methylpentadiene undergo condensation addition under heating and pressure conditions to obtain a reaction product. 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde and 3,5,6-trimethyl-3-cyclohexenecarbaldehyde, the two reaction products are isomers of isocyclic citral The steps are as follows: Add quantitative 99% crotonaldehyde and 99% methylpentadiene (transferred from the privet aldehyde production line) to the reactor, start stirring, control the pressure at 0.4-0.5MPa, and control the temperature at 130-140 ℃, constant temperature reaction for 12 hours.

After the reaction is finished, cool down, the temperature drops to 40-50°C, the pressure drops to normal pressure, and it is transferred to a distillation pot for atmospheric distillation. The temperature of the distillation pot is controlled at 80-90°C, and the unreacted crotonaldehyde, Methylpentadiene is distilled off, condensed and recycled to the isocyclic citral reaction kettle, and distilled at a temperature of 80-90°C until no distillation occurs; the liquid phase in the still is cooled to obtain the crude isocyclic citral.

Transfer the crude isocyclic citral to a rectification kettle for vacuum vacuum rectification, control the pressure to less than -0.08MPa, and temperature 110-130°C, collect the condensed and rectified products to obtain 99% isocyclic citral products. The front fraction (including crotonaldehyde, methylpentadiene, etc.) and distillation residue (containing crotonaldehyde, methylpentadiene, impurities, etc.) are collected as hazardous waste for outsourcing treatment. The main reaction chemical reaction equation is:

About Products:
If you need Isocyclocitral as a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Isocyclocitral manufacturer and supplier, ZSpharmac will provide Isocyclocitral raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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