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Isobutyl Acetate CAS 110-19-0

Molecular Formula: C6H12O2

Formula Weight: 116.16

ZSpharmac: Isobutyl Acetate Supplier Cosmetic Raw Materials

Product Name: Isobutyl Acetate
CAS No: 110-19-0
Purity: 99%

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Basic Info

Product Name:Isobutyl Acetate
Other Names:,2-Methylpropylacetate
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Clear Liquid
EINECS No.:203-745-1
Storage:Store Below +30°C.
Provide:Isobutyl Acetate MSDS;
Isobutyl Acetate COA

What is Isobutyl Acetate?

Isobutylacetate (English Isobutylacetate), also called isobutyl acetate, is the esterification product of acetic acid and 2-butanol. It is a water-white liquid with a soft fruity ester aroma. It is a little soluble in water as well as miscible in ethanol as well as ether.miscible with various organic solvents such as alcohols, ethers as well as hydrocarbons, as well as is primarily used as a diluent for nitrocellulose paint as well as perchlorethylene paint, a solvent for nitrocellulose as well as paint, and also can likewise be utilized as butyl acetate as well as methyl isobutyl A different solvent to ketones, it is additionally made use of as a part of fragrances, a diluent for plastic printing pastes, and an extractant in the pharmaceutical industry.
Sec-butyl acetate has excellent solubility to lots of materials, as well as its solubility residential or commercial properties are similar to n-butyl acetate and isobutyl acetate. It can be used industrially as a solvent for manufacturing nitrocellulose paint, acrylic paint, polyurethane paint, and so on. These paints Course can be used as airplane wing layers, fabricated natural leather coatings, auto finishes, etc. It can commonly change n-butyl acetate as well as isobutyl acetate in paint formulations. In metallic flash paint, cellulose acetate butyrate can be liquified with sec-butyl acetate to acquire a 15% to 20% solution.

Isobutyl Acetate Property

Melting point 

-99 °C (lit.)

Boiling point 

115-117 °C (lit.)


0.867 g/mL at 25 °C (lit.)

vapor density 

>4 (vs air)

vapor pressure 

15 mm Hg ( 20 °C)

refractive index 

n20/D 1.39(lit.)


71 °F

storage temp. 

Store below +30°C.


water: soluble5.6g/L at 20°C






5 (4g/l, H2O, 20℃)


Agreeable fruity odor in low concentrations, disagreeable in higher concentrations; mild, characteristic ester; nonresidual.

PH Range


Odor Threshold


Odor Type


explosive limit


Water Solubility 

7 g/L (20 ºC)


Isobutyl Acetate Applications

Isobutyl acetate has solid solubility and is mainly used as a diluent for nitrocellulose paint, perchlorethylene paint and also plastic printing paste. It can likewise be made use of as a solvent. As a result of its fruity and floral fragrance, it is usually used as a fruit essence and a modifier for increased fragrance. Isobutyl acetate has comparable solvent buildings to n-butyl acetate as well as methyl isobutyl ketone, so it can be used to replace them in many cases.

Isobutyl acetate and water can create the lowest azeotrope and also can be utilized as an entrainer in the azeotropic purification process. In the azeotropic purification process of industrial manufacturing of terephthalic acid, isobutyl acetate is included as an entrainer to continually eliminate the response by-product water, advertise the response, and also improve the return and top quality of terephthalic acid. Chien et al. examined the process layout as well as control of the heterogeneous azeotropic purification process for acetic acid dehydration. The results showed that compared to the acetic acid dehydration procedure without including an entrainer, the process utilizing isobutyl acetate as the entrainer has a longer lifetime. The overall expense can be minimized by 45%.

In summary, the research study development in the synthesis of isobutyl acetate is primarily mirrored in the preparation of brand-new catalysts as well as advancement in process style. As a brand-new sort of stimulant, ionic liquids have the following advantages: high catalytic activity and also selectivity; ionic fluids are practically non-volatile, so they are easy to separate from the response system; ionic liquids are steady and also can be recycled multiple times without affecting catalytic task. Consequently, using ionic liquids as catalysts for the synthesis of isobutyl acetate has great prospective for development.

Preparation of Isobutyl Acetate

Utilizing acetic acid and also isobutanol, through the esterification reaction, and utilizing strong oxalic acid as a catalyst to manufacture isobutyl acetate. Isobutyl acetate is a little soluble in water, miscible in alcohol and ether, and also unrefined isobutyl acetate can be removed. The crude essence might include the byproduct diisobutyl oxalate (boiling point: 240.1 ° C). Isobutyl acetate (boiling point: 118 ° C) can be purified by purification based upon their various boiling points. The main element of the cleansed option is isobutyl acetate, and a percentage of this remedy is required to determine the refractive index to figure out the item.

There is isobutanol-water azeotrope in this experimental system, azeotropic point 89.9 ℃; Isobutyl acetate-water azeotrope, azeotropic point 87.45 ℃. At various phases of the response, water can be obtained of the system by using various azeotropes. After condensation and also water separation, the alcohol and also ester return to the reaction system. In order to enable the alcohol to go back to the response system in time to complete the reaction, pre-measured water should be included in the water separator before the response starts, to make sure that the water surface is slightly less than the reduced edge of the reflux branch pipe of the water separator. Throughout backflow, just a thin layer of oil exists on the water surface area. Throughout the operation, the apart water is constantly let go to maintain the thickness of the oil layer constant.

There are 3 methods busy for the straight prep work of esters from acids and also alcohols.

The first is the azeotropic purification water separation technique. The produced ester and water are vaporized in the form of an azeotrope. After condensation, the water is separated through the water separator, as well as the oil layer is gone back to the activator.

The second is the removal and esterification approach, including a solvent to liquify the catalyst and also the generated ester in the solvent and different it from the water layer.

The 3rd is the straight reflux method, one reactant extra, straight reflux. It is far better to prepare iso-J acetate by azeotropic distillation. In order to eliminate the water created in the catalyst, usage ester, acid and also water to develop binary or ternary azeotrope, and adopt azeotropic purification to separate water. Make the produced ester as well as water escape in the form of azeotrope, and also after condensation, the water layer is divided through the water separator, and also the oil layer is returned to the activator.

Purification of Isobutyl Acetate:

Pour all the liquid in the three-neck flask and water separator into the separatory funnel, wash it three times with deionized water and release the lower water layer, and add saturated Na2CO3 solution dropwise to the oily liquid in the upper layer until no bubbles are generated (adjusted to Neutral), remove the lower layer solution, wash the ester layer with saturated NaCl solution (to reduce the solubility of isoacetic acid ester), and extract and separate the liquid, pour the ester layer into the Erlenmeyer flask from the upper mouth of the funnel, and use a small amount of anhydrous MgSO4 dry. Pour the dried ester into a single-necked flask, connect to a distillation device for distillation, and collect the fraction between 118° and 120° to obtain the isobutyl acetate product. This product is a colorless transparent liquid with a fruity aroma. When distilling, if the distilled product is turbid, it means that the distillation system or the ester has not been completely dried.

About Products:
If you need the cosmetic raw material Isobutyl Acetate, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Isobutyl Acetate, our company, ZSpharmac will provide Isobutyl Acetate raw materials to customers around the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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