Hydroxypropyl Methyl Cellulose CAS 9004-65-3

A sheet pulp of kraft pulp acquired from ache wood with an α-cellulose product of 97%, an inherent thickness of 720 ml/g, in addition to additionally a length-average fiber size of 2.6 mm was submersed in a 49% NaOH fluid choice at 40 ° C. 50 seconds; the resulting pulp sought that pushed to eliminate excess 49% NaOH fluid solution to obtain alkali cellulose. The weight proportion of (49% NaOH fluid service) to (strong web material in pulp) in the dipping task was 200. The weight proportion of (the NaOH component in the alkali cellulose therefore gotten) to (the solid material in the pulp) was 1.49. The alkali cellulose (20 kg) because of this obtained was put in a jacketed anxiety activator with indoor mixing, and after that left along with purged with nitrogen to totally get rid of oxygen from the activator. Next off, interior mixing was done while controlling the temperature degree in the activator to 60 ° C. Afterwards, 2.4 kg of dimethyl ether was consisted of, and also the temperature level in the activator was taken care of so pertaining to be kept 60 ° C. After including dimethyl ether, add dichloromethane to ensure that the molar percentage of (dichloromethane) to (NaOH part in alkaline cellulose) is 1.3, include propylene oxide to ensure that (propylene oxide) along with (NaOH element in the pulp) The weight percentage of strong content) was transformed to 1.97 while managing the temperature level in the activator from 60 ° C to 80 ° C. After including methyl chloride along with propylene oxide, the temperature level in the reactor was managed from 80 ° C to 90 ° C. On top of that, the responses was continued at 90 ° C for 20 minutes. After that, the gas was broadcast vent from the activator, as well as in addition the crude hydroxypropylmethylcellulose was gotten from the reactor. The temperature level of the raw hydroxypropylmethylcellulose at the time of getting was 62 ° C. The progressing 50% item size in a collective weight-based fragment measurement blood circulation identified based upon the proportion of unrefined hydroxypropyl methylcellulose experiencing the openings of five filters, each with a different opening dimension, was evaluated. Consequently, the regular little bit size of the unrefined little bits was 6.2 mm. The raw hydroxypropyl methylcellulose for that reason acquired was presented right into a continuous biaxial kneader (KRC Kneader S1, L/D = 10.2, interior quantity 0.12 litres, turning rate 150 rpm) at a rate of 10 kg/hr to acquire decay of raw hydroxypropyl methylcellulose. As a result of comparable dimension utilizing 5 filters with many opening dimensions, the common bit size thereof was 1.4 mm. Include 80 ° C cozy water to the corroded crude hydroxypropyl methylcellulose in a container with jacketed temperature level control in an amount such that (hydroxypropylmethyl in the broken down unrefined hydroxypropyl methylcellulose The weight percentage of the quantity of cellulose) to (the total amount of slurry) was become 0.1 to get a slurry. The slurry was combined at a continual temperature of 80 ° C for 60 minutes. Next off, the slurry was fed to a turning tension filter (thing of BHS-Sonthofen) whose rotation rate was 0.5 revolutions/minute as well as also which was warmed beforehand. The temperature level of the slurry was 93 ° C. A pump is used to offer the slurry, in addition to the discharge tension of the pump is 0.2 MPa. The opening dimension of the filter of the turning stress and anxiety filter is 80μm, in addition to the filtration area is 0.12 m2. The slurry provided to the rotating pressure filter is changed to a filter cake by filtering system with the filter. After using 0.3 MPa vapor to the filter cake hence obtained, warm water at 95 ° C was provided in an amount such that the weight percent of (warm water) to (strong internet material of cleaned up hydroxypropylmethylcellulose) was 10.0. Later on, filter through the filter. Relaxing water is provided with a pump with a discharge stress and anxiety as well as anxiety of 0.2 MPa. After cozy water is provided, hefty vapor of 0.3 MPa is offered. Then, the cleaned thing on the surface of the filter is gotten rid of by a scrape and released out of the cleansing maker. The tasks from feeding the slurry to releasing the cleaned up thing are done constantly. As a result of dimension utilizing a heat-drying kind hygrometer, the water net material of the thus-discharged washed item was 52.8%. The washed thing released from the revolving tension filter was dried out making use of an air clothing dryer at 80 ° C., as well as likewise grated in a result mill Triumph mill to acquire Hydroxypropyl Methyl Cellulose.