Zhishang Chemical

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Zhishang Chemical

Hydroxyethylurea CAS 2078-71-9

Molecular Formula: C3H8N2O2

Formula Weight: 104.11

ZSpharmac: Hydroxyethylurea Supplier

Product Name: Hydroxyethylurea
CAS No: 2078-71-9
Purity: 99%

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Basic Info

Product Name:Hydroxyethylurea
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Almost White Powder to Crystal
EINECS No.:640-848-4
Storage:Sealed in Dry,Room Temperature
Provide:Hydroxyethylurea MSDS;
Hydroxyethylurea COA

What is Hydroxyethylurea?

Hydroxyethylurea is a good moisturizer, which is widely used in cosmetic moisturizing products. It has a similar effect to glycerin, but compared with glycerin, hydroxyethylurea has a more significant moisturizing effect. Its main feature is to provide moisturizing function to skin care products without sticky feel, and at the same time, it can increase skin elasticity, replenish skin moisture, and has good compatibility with various skin care ingredients, mild and non-irritating. Hydroxyethylurea is also cost-effective. Compared with expensive moisturizers, hydroxyethylurea can achieve the same effect at a lower formulation cost.

Hydroxyethylurea Property

Melting point 164-169 °C(lit.)
Boiling point 254.3±32.0 °C(Predicted)
density 1.222±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form powder to crystal
color White to Almost white
Water Solubility almost transparency


Hydroxyethylurea Uses

Best Moisturizer
Our skin has urea, which uses the natural urea ingredient found in the skin to moisturize.
Therefore, using products that contain hydroxyethyl urea helps our skin to be optimally moisturized (since it is similar to the natural urea ingredient found in the skin):
1.Hydroxyethylurea helps to balance the amount of water and oil in the skin.
2. At the same time, Hydroxyethylurea promotes the formation of keratin necessary for the skin.
3.Hydroxyethylurea is favored for its moisturizing effect without greasy skin.
4. When Hydroxyethylurea is used in combination with other active ingredients, the skin care and nourishing effect is better.

Gentle and Gentle Exfoliation
Hydroxyethylurea has been proven by experts to be one of the most important nutrients for the skin when it wants to remove dead cells. When using products with a high concentration of Hydroxyethylurea, the exfoliating effect of this active ingredient will leave you with revitalized skin. In particular, hydroxyethylurea does not cause skin irritation like other chemical exfoliants. Keep your skin safe from harm! Hydroxyethylurea is very gentle and soothing on the skin when exfoliating.

Enhance skin resistance
External factors such as polluted air and harmful UV rays can make your skin age “giddy” quickly if the skin barrier is weakened. After using Hydroxyethylurea, your skin will be repaired and the skin barrier will become healthier. Skin irritation is reduced. The pleasant sensation of Hydroxyethylurea makes it a “companion” for all skin types, including the most sensitive.

Hydroxyethylurea Mimics of Unnatural Amino Acid Substitutions

  • γ-Secretase, with properties of an aspartyl protease, moderates intramembrane proteolysis of β-amyloid precursor protein (APPLICATION) and Notch, and is thought about a significant gamer in the development of Alzheimer’s illness (AD) therapies pharmacological target. To recognize compounds that obstruct γ-secretase-mediated proteolysis, we utilized a highly delicate cell-based press reporter gene assay for γ-secretase in which Gal4/VP16-tagged C99-APP was expressed as γ-secretase bosom by Gal4 γ-secretase launches the/ VP16-tagged APP intracellular domain name which subsequently activates Gal4-driven expression of the luciferase reporter genetics. Utilizing this reporter assay, we demonstrate that recently manufactured Hydroxyethylurea peptidomimetics, including unnatural amino acid moieties at the P1′ and/or P3′ settings, potently inhibit γ-secretase task and considerably minimize Abeta manufacturing. γ-secretase-dependent S3 cleavage of Notch was additionally continually blocked by these Hydroxyethylurea, as shown by minimized manufacturing of Notch intracellular domains, a requirement for activation of Notch signaling.Restraint of Notch signaling by active Jia compounds efficiently advertises neuronal differentiation of neuroblastoma cells and also hinders tumorigenesis and also hatred of neuroblastoma. Our outcomes recommend that Hydroxyethylurea peptoids having abnormal amino acid replacements may represent an unique class of γ-secretase preventions with improved security,

About Products:
If you need Hydroxyethylurea as a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced manufacturer and supplier of Hydroxyethylurea, ZSpharmac will provide Hydroxyethylurea raw materials for customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Hydroxyethylurea Quotation