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Hydroxyethyl Cellulose Sigma CAS 9004-62-0

Molecular Formula: C29H52O21

Formula Weight: 0

ZSpharmac: Hydroxyethyl Cellulose Sigma Supplement

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Product Name: Hydroxyethyl Cellulose Sigma
CAS No: 9004-62-0
Purity: 99%

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Basic Info

Product Name:Hydroxyethyl Cellulose Sigma
Other Names:2-Hydroxyethyl Cellulose
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Light Brown Powder
EINECS No.:618-387-5
Provide:Hydroxyethyl Cellulose Sigma MSDS;
Hydroxyethyl Cellulose Sigma COA

What is Hydroxyethyl Cellulose Sigma?

Hydroxyethyl Cellulose Sigma(HEC) is an important fiber with the third largest output in the world after carboxymethyl cellulose (CMC) and Hydroxyethyl Cellulose Sigma (HPMC). It is also a cellulose ether variety to be developed in the domestic market in the next few years. Hydroxyethyl Cellulose Sigma is a non-ionic cellulose single ether made from cotton and wood by alkalization and ethylene oxide etherification. Due to the non-ionic characteristics of no interaction with positive and negative ions and good compatibility, Hydroxyethyl Cellulose Sigma can be used as a coating agent, binder, cement and gypsum auxiliary, thickening agent, suspending agent, and pharmaceutical excipients. , antifogging agent, oil well fracturing fluid, drilling treatment agent, fiber and paper sizing agent, wetting solution, dispersing agent, film auxiliary agent, ink auxiliary agent, preservative and antifouling agent, cosmetics, toothpaste, film casting agent, Thermal recording paper, lubricants, sealants, gels, waterproofing agents, bactericides, bacterial culture media, etc., are widely used in coatings, petroleum, construction, daily chemicals, polymer polymerization and textile industries.

Hydroxyethyl Cellulose Sigma Properties:

Melting point 288-290 °C (dec.)
density 0.75 g/mL at 25 °C(lit.)
storage temp. 2-8°C
solubility H2O: ≤5 wt. % at 20 °C
form powder
color Light brown powder
PHpH(20g/l,25℃) : 5.0~8.0
Water Solubility almost transparency


Various Applications of Hydroxyethyl Cellulose Sigma

Coatings are the biggest application location of Hydroxyethyl Cellulose Sigma. Hydroxyethyl Cellulose Sigma is used as a dispersant, thickener and also pigment putting on hold agent in the manufacturing process of latex finishes to support the thickness of the product, reduce jumble, make the paint movie smooth and also smooth, as well as also make the latex covering have far better rheology. Stands up to high shear toughness as well as gives excellent leveling, scrape resistance and also pigment uniformity. At the same time, Hydroxyethyl Cellulose Sigma has superb workability. Paints thickened with Hydroxyethyl Cellulose Sigma can be applied by brushing, rolling, loading, spraying and also various other building approaches, which are labor-saving, challenging to leak, sag, and sprinkle. Much less benefits. Hydroxyethyl cellulose has outstanding color growth and also superb miscibility with most colorants as well as connecting products, to ensure that the created latex paint has excellent shade consistency as well as security. At the China International Coatings Event kept in Guangzhou at the end of 2012, Ashland introduced a brand-new Natrosol Performax Hydroxyethyl Cellulose Sigma with an innovation covering thickening innovation, which makes it possible for the hydroxyethyl cellulose fragments to stand up to the low-speed shearing of the finish. Disperses swiftly and also thoroughly.

Hydroxyethyl Cellulose Sigma is generally utilized as a thickening stabilizer in the oil area therapy process. It has excellent thickening effect, strong and secure sand suspension capability, heat resistance, high salt capability, tiny pipe resistance, much less liquid loss, and also gel splitting. It is a good oilfield chemical with the qualities of rapid speed and also low residue. It has actually been extensively used in boring, completion, sealing and various other oil manufacturing operations abroad in the 1960s. Hydroxyethyl Cellulose Sigma is likewise made use of as a fluid loss control representative in oilfield applications.

Hydroxyethyl Cellulose Sigma is mostly made use of as thickening representative, colloid safety agent, adhesive, distributing representative, stabilizer, suspending representative, film-forming representative and sustained-release material in the fields of food as well as medication. Ointments, eye declines, oral liquids, solid tablets, capsules and various other dosage types. On top of that, Hydroxyethyl Cellulose Sigma can likewise be made use of for hemostatic gauze. Hydroxyethyl cellulose soluble hemostatic gauze is an ideal hemostatic product.

Given that non-ionic Hydroxyethyl Cellulose Sigma transcends to ionic CMC in terms of movie development, anti-enzyme, moisture retention, pH security, and so on, its application array in the field of daily chemicals is expanding., hair shampoo, hair lotion, dietary cream and fat, cream, cream, ointment as well as various other items have actually been extensively used. CMC is extra conscious high concentrations of ions, which will minimize the bond performance of CMC, which is restricted in high-quality, special-effect toothpastes. As a binder, hydroxyethyl cellulose boosts the performance of the binder against high focus of ions, considerably enhances the storage stability of the paste, and also extends the storage time of the tooth paste.

Along with the above primary application areas, Hydroxyethyl Cellulose Sigma is additionally utilized in numerous fields of national income. As an example, in the fabric area, Hydroxyethyl Cellulose Sigma-treated cotton, synthetic fibers or blends can improve their residential properties such as abrasion resistance, dyeability, fire resistance and also discolor resistance, in addition to improve their body stability (shrinking resistance).) and also toughness, specifically for artificial fibers, making them breathable and minimizing fixed electricity. It has a thickening impact in the printing and dyeing paste and also can be utilized as a provider for dyes, to make sure that the dyes are well dispersed, offering exceptional permeability as well as the correctness as well as security of patterns and also shades. Additionally, in the field of papermaking, Hydroxyethyl Cellulose Sigma can be utilized as a sizing representative, a reinforcing representative and a paper modifier.

Properties of Hydroxyethyl Cellulose Sigma

The main residential properties of Hydroxyethyl Cellulose Sigma are that it is soluble in cold water and warm water, and has no gel properties. It has a variety of alternative degree, solubility and also thickness. rainfall. Hydroxyethyl Cellulose Sigma service can create a transparent film, and also has the qualities of non-ionic type that does not connect with ions and has great compatibility.

① Heat as well as water solubility: Compared to methyl cellulose (MC), which is only soluble in cold water, Hydroxyethyl Cellulose Sigma can be dissolved in hot water or cold water. Variety of solubility as well as thickness buildings, and also non-thermal gelation.

② Salt resistance: Due to its non-ionic kind, it can exist side-by-side with other water-soluble polymers, surfactants and salts in a wide range. As a result, compared to ionic carboxymethyl cellulose (CMC), Hydroxyethyl Cellulose Sigma has better salt resistance.

③ Water retention, leveling, film-forming: its water-retaining capacity is twice that of methyl cellulose, with exceptional circulation guideline as well as exceptional film-forming, fluid loss reduction, miscibility, safety colloid sex.

Study on Properties of Hydroxyethyl Cellulose Modified WPU

Over the last few years, people’s understanding of environmental protection has slowly boosted. As an environmentally friendly finishing, water-based polyurethane (WPU) has attracted much attention as a result of its low natural volatiles, reduced air pollution, security and reliability, and also very easy operation. Nonetheless, the existing waterborne polyurethane has some problems in application, such as low solidity, low bond, inadequate water resistance as well as wear resistance. Consequently, the alteration of WPU material has ended up being the focus of study. Modification approaches can be mainly divided into two groups: one is molecular style of polyurethane, presenting some unique frameworks in the process of polyurethane synthesis, enhancing the difficult sector of the molecular chain, and also improving the firmness of the polymer itself. For instance, Wang Haifeng et al. included epoxy resin in the process of manufacturing polyurethane, as well as study on the obtained covering revealed that the solidity, bond as well as impact resistance of the finish movie were enhanced; Additional cross-linking between to improve hardness, wear resistance, water resistance and also other buildings.

As one of the most abundant natural polymer in nature, cellulose has the advantages of bountiful resources resources, sustainable, biodegradable, eco-friendly, and also big outcome. Hydroxyethyl cellulose (HEC) is a crucial cellulose derivative. It is a multifunctional compound with great film-forming residential or commercial properties. It can participate in the synthesis response of polyurethane to create a partial network framework to improve efficiency.

In this paper, toluene diisocyanate (TDI) as well as polyether diol (N210) are utilized as the main resources TDI including benzene ring structure can boost the mechanical residential or commercial properties of waterborne polyurethane. At the same time, hydroxyethyl cellulose was added for modification, and the gotten tweaked polyurethane was tested for efficiency. The outcomes revealed that the addition of HEC can boost the efficiency of water-based polyurethane.

1.1 Experimental products.

Toluene Diisocyanate (TDI): AR, Shanghai Ebipe Chemical Reagent; Polyether Diol (N210, Mn= 1000): Industrial Quality, Jining Hongming Chemical Reagent; 2,2-Dimethylolpropionic Acid (DMPA): AR, Tianjin Xiens Biochemical Innovation Co., Ltd.; Hydroxyethyl Cellulose (HEC): AR, Chengdu Kelong Chemical Reagent Factory; Diethylene Glycol (DEG): AR, Tianjin Damao Chemical Reagent Manufacturing facility; Dibutyltin dilaurate (DBTDL): AR, Tianjin Fuchen Chemical Reagent Factory; Triethylamine (TEA): AR, Tianjin Beilian Fine Chemicals Factory; Acetone: AR, Sinopharm Team; Methylformamide: AR, Tianjin Bodi Chemical.

1.2 Synthesis of Hydroxyethyl Cellulose Sigma customized WPU

Polyether glycol (N210), 2,2-dimethylolpropionic acid (DMPA), diethylene glycol (DEG), and Hydroxyethyl Cellulose Sigma were pre-dried at 60 ° C for 12 h. Put 20g N210 and 3.14 g TDI into a 250mL three-necked flask geared up with mechanical stirring and condensation reflux gadget, as well as warmth the reactant to 75 ℃ for 30min under nitrogen defense. DMPA dissolved in a percentage of DMF was added dropwise to the response system, as well as 3.14 g of TDI was added after 10 mins to respond for thirty minutes. After that 2– 3 declines of DBTDL were added as a stimulant to advertise the reaction. Include HEC with mass portions of 0%, 0.1%, 0.5%, 1%, as well as 2% respectively for modification, boost the speed as well as warm up to 80 ° C, and react for 4 h. Throughout the reaction, the viscosity of the response system was managed by adding a proper quantity of acetone, after that cooled down to area temperature, and a small amount of DEG was included in respond for 30min for chain extension, then TEA was included for 30min neutralization response, as well as ultimately 50mL of deionized water was included as well as the rotational rate was raised to accomplish solid shear emulsification for 30min, as well as the acetone is eliminated under minimized stress to get a Hydroxyethyl Cellulose Sigma customized water-based polyurethane emulsion with a particular strong material.

1.3 Testing as well as Characterization

Infrared spectroscopy analysis: The latex films were examined utilizing a Vector-22 infrared spectrometer from Brucker, Germany.

Emulsion thickness test: test with NDJ-5S electronic rotational viscometer (Shanghai Trick Instrument Co., Ltd.) at space temperature.

Emulsion solid content test: Evaluate a particular mass of modified WPU emulsion as well as record the mass as M0 and add it to the beaker, and the mass of the beaker is M1. Location the sample in an oven at 90 ° C, take it out after 4 hours, cool it as well as weigh it, duplicate a number of times until the mass adjustment is less than 0.001 g. The overall mass of the dried example and beaker is recorded as M2. The strong content of the emulsion is the


wt (%) = (M2-M1 )/ M0 × 100%.

Solution security test: put 20mL of solution and an equal quantity of empty control into a 80-1 kind centrifuge symmetrically, centrifuge at a speed of 3000r/min for 30min, take out the centrifuge test tube after centrifugation, as well as observe whether the coating has actually sped up, if no Precipitation and also covering without delamination is thought about to be steady for 6 months.

Paint film solidity test: describe GB/T 1727-1992 to prepare paint movie by brushing method, and also use QHQ-A pencil firmness tester (Dongguan Huaguo Precision Instrument Co., Ltd.) to perform pencil solidity examination according to GB/T 6739-2006.

Water absorption performance examination: Cut the finishing movie right into an ideal dimension, document the weight as m0, saturate it in deionized water for 24 hours, take it out and wipe it completely dry, as well as tape the weight as m1, after that the water absorption rate of the movie is:.

Water absorption (%) = (m1-m0 )/ m0 × 100%.

Repaint movie adhesion examination: Use QFH-HG600 paint movie cross-checker (Dongguan Huaguo Precision Tool Co., Ltd.) to gauge the attachment performance of waterborne polyurethane paint, refer to GB/T 9286-1998.

2.1 Infrared Analysis.

Infrared tests were carried out on Hydroxyethyl Cellulose Sigma (HEC), unmodified polyurethane movie (WPU), as well as changed polyurethane movie (HEC-WPU). It can be seen from curve A in Number 1 that 420 ~ 750cm-1 is the intra-ring vibration absorption peak of the sugar ring, which is the characteristic group of HEC particle. It can be seen from the contrast of contours B and C that both are at 3313., 1723, 1592cm-1 appeared infrared absorption heights. Among them, the stretching vibration of -NH- at 3313cm-1, the extending vibration optimal of -NH-C =O- at 1723cm-1, and also the flexing vibration optimal of -NH- at 1592cm-1, it can be seen that -OH Responds with -NCO as well as creates a urethane bond. At the same time, the peak shapes of contours B as well as C are obviously various at 480-690 cm-1, which may be brought on by the overlapping of the vibration absorption peak of the glucose ring in the HEC molecule and also the absorption optimal of the polyurethane there. Infrared analysis can prove that HEC particles are successfully grafted right into the polyurethane molecular chain, as well as the acquired product is the target item.

2.2 Impact of hydroxyethyl.

cellulose on emulsion residential properties.
It can be seen from Table 1 that with the rise of HEC content, the viscosity of the polyurethane finish progressively raises, as well as the solid web content of the emulsion very first increases and after that decreases. This might be because of the response of hydroxyl groups in HEC with isocyanate groups to present cellulose molecular chains into polyurethane particles, and also the molecular weight and also section length boost. The expanding sectors are much more susceptible to complexity, causing raised viscosity. At the same time, the unreacted hydroxyl groups in HEC form hydrogen bonds with polyurethane to prevent the activity of molecular chains, thus further enhancing the thickness of the system. When the HEC content boosts to a particular degree, the thickness of the system is as well large, the emulsification procedure is difficult, the security of the resulting solution becomes bad, and the storage time comes to be shorter.

2.3 Impact of Hydroxyethyl Cellulose Sigma on film residential properties.

The buildings of the water-based polyurethane movie with different HEC materials are listed in Table 2. From Table 2, it can be seen that the pencil firmness of the film is enhanced after including hydroxyethyl fiber, the water absorption efficiency is reduced first and afterwards boosted, and also the bond degree is boosted. The fad is to enhance initial and afterwards lower. This is since the hydroxyl groups in cellulose can react with the isocyanate teams in the polyurethane prepolymer to create a cross-linked structure, therefore boosting the pencil solidity and also bond properties of the film, and the cross-linked framework also makes it tough for water particles to get in the molecular chain void. middle. When the quantity of cellulose included is also huge, unreacted hydroxyl groups remain in the emulsion, which adversely impacts the hardness, water absorption as well as attachment of the polyurethane film. The modified polyurethane done finest when the cellulose content was 0.5%.

As an eco-friendly finish, waterborne polyurethane has come to be the focus of research study on its adjustment. In this paper, TDI, N210, etc are utilized as the main basic materials to prepare the polyurethane prepolymer beforehand. Hydroxyethyl Cellulose Sigma was made use of as modifier to react with prepolymer, and also the impact of hydroxyethyl cellulose content on the properties of WPU emulsion and film was studied. The examination results program that the enhancement of HEC can improve the pencil hardness, attachment and also various other homes of the WPU film. When the cellulose web content is 0.5%, the film performance is best.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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