Zhishang Chemical

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Zhishang Chemical

Hydroxyacetone CAS 116-09-6

Molecular Formula: C3H6O2

Formula Weight: 74.08

ZSpharmac: Hydroxyacetone Raw Material Supplier

Product Name: Hydroxyacetone
CAS No: 116-09-6
Purity: 99%

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Basic Info

Product Name:Hydroxyacetone
Other Names:1-Hydroxy-2-Propanon
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless liquid
EINECS No.:204-124-8
Provide:Hydroxyacetone MSDS;
Hydroxyacetone COA

What is Hydroxyacetone?

Hydroxyacetone is really easy to polymerize right into dimers. In addition to having hydroxyl and carbonyl buildings, it is furthermore quickly oxidized by cuprous oxide and forms hydrazone with phenylhydrazine. Hydroxyacetone can respond with acids to create hydroxypyruvate, which can be used to manufacture substances with a hydroxyacetone structure. Hydroxyacetone can undertake a carbonyl addition feedback, reacting with carbonyl compounds such as aldehydes and ketones to create brand-new hydroxyacetone derivatives. This reaction is generally commonly used in the preparation job of chemical reagents and intermediates.

Hydroxyacetone Property

Melting point 

-17 °C (lit.)

Boiling point 

145-146 °C (lit.)


1.082 g/mL at 25 °C (lit.)

vapor pressure 

9.01hPa at 25℃

refractive index 

n20/D 1.425(lit.)


133 °F

storage temp. 



water: miscible




clear liquid


Colorless liquid

Specific Gravity

1.090 (20/4℃)


at 10.00 % in dipropylene glycol. pungent sweet caramellic ethereal

Odor Type


Water Solubility 

Miscible with water, alcohol and ether.


Hydroxyacetone Application

Hydroxyacetone is a typically made use of natural chemical reagent. It is mostly utilized as an intermediate for all-natural synthesis and pharmaceutical compounds. It can be used for the synthesis of medicine bits and chemical particles. Hydroxyacetone can be made use of to prepare cosmetics, personal therapy products and pharmaceutical intermediates. Hydroxyacetone can be made use of as a sources for the synthesis of cosmetics and specific therapy items such as degreasing, hair color, conditioner, skin lotion, tooth paste, eating periodontal, and so forth. In the pharmaceutical location, hydroxyacetone is additionally an essential raw material for some pharmaceutical intermediates. This substance is made use of to produce imidazole materials, which can be used as reliable dental antihypertensive drugs.


In a totally dry reaction flask, mix hydroxyacetone (0.85 mL, 5 mmol), salt borohydride (0.2 g, 5.3 mmol) and ethanol (5 mL). The resulting response mix was mixed for 2 hours. After the response was finished, the response was really thoroughly quelled with thin down HCl (note the recognizable development of bubbles). After that consist of diethyl ether (5 mL) to the response combination for extraction, incorporate 100% natural stages and completely dry them over anhydrous MgSO4, filter to eliminate the desiccant and focus the filtrate under hoover to remove the solvent to obtain the product molecular.

Hydroxyacetone Chemical Reaction

Hydroxyacetone is simple to polymerize right into dimers. In addition to having hydroxyl and carbonyl residential or commercial properties, it is also conveniently oxidized by cuprous oxide and creates hydrazone with phenylhydrazine. Hydroxyacetone can respond with acids to create hydroxypyruvate, which can be utilized to manufacture substances with a hydroxyacetone framework. Hydroxyacetone can undergo a carbonyl addition response, responding with carbonyl compounds such as aldehydes and ketones to form brand-new hydroxyacetone derivatives. This reaction is usually widely utilized in the preparation of chemical reagents and intermediates.

Hydroxyacetone Production Method

Take potassium hydroxide, anhydrous methanol and ethyl formate and reflux together for 2 hours to prepare a methanol service of potassium formate. Warmth it with bromoacetone to reflux and react for 16 hours. After the reaction, cool to 0 ° C, strain the potassium bromide, distill the filtrate, and collect the 40-43 ° C (1.6 kPa) portion to acquire hydroxyacetone, with a return of 54-58%.

About Products:
If you need Hydroxyacetone as a cosmetic raw material, please contact our service staff directly and we will provide you with high-quality products at the best price.
As an experienced Hydroxyacetone manufacturer and supplier, our company, ZSpharmac, will provide Hydroxyacetone raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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