Zhishang Chemical

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Hinokitiol CAS 499-44-5

Molecular Formula: C10H12O2

Formula Weight: 164.2

ZSpharmac: Hinokitiol Raw Material Supplier

Product Name: Hinokitiol
CAS No: 499-44-5
Purity: 99%

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Basic Info

Product Name:Hinokitiol
Other Names:β-thujaplicin
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Solid
EINECS No.:207-880-7
Storage:Room Temperature
Provide:Hinokitiol MSDS;
Hinokitiol COA

What is Hinokitiol?

Hinokitiol is a naturally occurring monoterpene compound with the chemical name 2-hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one and its chemical formula It is C10H14O, sometimes also written as C10H18O. This is because its molecular structure may contain different oxidation states or the number of hydroxyl groups, and the chemical formulas provided in different documents are different. Hinokinol is mainly derived from the resin or wood of cypress plants such as red juniper (Chamaecyparis obtusa) and hinoki (Thuja plicata). It is a colorless to light yellow crystal or liquid with a fresh pine scent.

Hinokitiol Property

Melting point 50-52 °C(lit.)
Boiling point 140 °C10 mm Hg(lit.)
density 1.0041 (rough estimate)
refractive index 1.5190 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form solid
color White


The Uses of Hinokitol in Various Fields

Personal care and cosmetics industry:
Antibacterial preservative: Due to its strong antibacterial activity, hinokitiol is widely used in personal hygiene and skin care products such as toothpaste, mouthwash, skin cream, shampoo, shower gel, etc., as a natural antibacterial preservative to reduce the growth of harmful microorganisms , preventing problems such as skin diseases and bad breath.
Whitening agent: Hinoki alcohol has the effect of inhibiting tyrosinase activity, thereby reducing the production of melanin. It is used in the formulation of whitening products to help improve uneven skin tone and lighten spots.

Medical and health fields:
Medical device disinfection: Its strong antibacterial properties make it suitable for disinfection of medical device surfaces.
Pharmaceutical excipients: In some pharmaceutical preparations, hinokitiol can be used as an auxiliary ingredient to enhance drug stability or improve the effect of topical medication.

Food industry:
Food additive: In Japan, hinokitiol is a permitted food additive that can impart a specific flavor to food and help extend the shelf life of food due to its antibacterial properties.

Agriculture and Veterinary Sciences:
Insect repellents and pesticides: Hinoki alcohol has a repellent effect on a variety of pests, so it can be used to produce environmentally friendly repellents to protect crops and livestock from parasites.

Household cleaning and environmental disinfection:
Household cleaner: Added as an active ingredient to household cleaners to enhance its sterilization and deodorization capabilities, making the home environment cleaner and hygienic.

Research and Biotechnology:
Laboratory research: Juniperol is used as a research tool in biochemical and medical research to explore its antibacterial mechanisms and to develop potential new drugs.

Features and Benefits of Hinokitiol


Zhu YJ, Qiu L, Zhou JJ, Guo HY, Hu YH, Li ZC, Wang Q, Chen QX, Liu B. Inhibitory effects of hinokitiol on tyrosinase activity and melanin biosynthesis and its antimicrobial activities. J Enzyme Inhib Med Chem. 2010 Dec;25(6):798-803. doi: 10.3109/14756360903476398. Epub 2010 Jun 28. PMID: 20578978.

As a company specializing in the production and supply of Hinokitiol raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the Hinokitiol raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Hinokitiol Quotation