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Hexadecanoic Acid CAS 57-10-3

Molecular Formula: C16H32O2

Formula Weight: 256.42

ZSpharmac: Hexadecanoic Acid Supplier

Product Name: Hexadecanoic Acid
CAS No: 57-10-3
Purity: 99%

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Basic Info

Product Name:Hexadecanoic Acid
Other Names:Palmitic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White or Almost White Flakes
EINECS No.:200-312-9
Storage:Room Temp
Provide:Hexadecanoic Acid MSDS;
Hexadecanoic Acid COA

What is Hexadecanoic Acid?

Hexadecanoic Acid, likewise referred to as palmitic acid, is a white crystal at room temperature, insoluble in water, soluble in organic solvents such as ether, chloroform, and acetone. Palmitic acid is among one of the most commonly distributed fats in nature. It is commonly present in various oils in the form of glycerides, such as tallow fat, palm oil, lacquer fat, cottonseed oil, soybean oil, peanut oil, corn bacterium oil, fish oil, milk fat, cattle, sheep, pig fat, and so on. Its esters (that is, all-natural waxes) created with higher saturated monohydric alcohols are commonly located in lots of kinds of pets and also plants.

Hexadecanoic Acid Property

Melting point 

61-62.5 °C(lit.)

Boiling point 

351.5 °C


0.852 g/mL at 25 °C(lit.)

vapor pressure 

10 mm Hg ( 210 °C)

refractive index 



>230 °F

storage temp. 

room temp


chloroform: 0.5 M, clear, colorless






White or almost white

Water Solubility 




Hexadecanoic Acid Uses

  1. Hexadecanoic Acid is used as a reference product for gas stage analysis.
  2. Hexadecanoic Acid is utilized to determine water firmness as well as calcium, magnesium, barium, lead, mercury, zinc. Organic synthesis, manufacture of various palmitic acid steel salts as well as waterproofing agents.
  3. Hexadecanoic Acid is a basic material for the manufacture of various other food additives (fat glycerides, fatty acid sorbitan esters, sugar esters, etc). It can likewise be utilized as a flavor component. According to FEMA policies, the maximum dosage in seasonings is 1.0 mg/kg.
  4. Hexadecanoic Acid is a component in the production of candle lights, soaps, oils, softeners and also artificial detergents. Palmitic acid is used to make unsmelling chloramphenicol and various palmitic acid steel salts. Its salt or potassium salts can be used as emulsifiers in emulsion polymerization. Light weight aluminum and also zinc salts are utilized in lubricants, paints, oil blacks and also enhancers. in plastic. This product has a special scent as well as taste. According to the guidelines of my country’s GB2760-89, it can be used to prepare different edible seasonings, as well as also utilized as a basic material for defoamers and various other preservative.

Compare Synthesis of Hexadecanoic Acid with Beta-Oxidation!

The biosynthesis of Hexadecanoic Acid is carried out in chloroplasts and protoplasts in plants to synthesize saturated fatty acids with 4 to 16 carbons and more than 16 carbons. Animals are carried out in the cytosol, only 16-carbon saturated fatty acids are synthesized, and fatty acids longer than 16 carbons are synthesized in the endoplasmic reticulum or mitochondria. As far as the synthesis process of 16-carbon saturated fatty acids in the cytosol is concerned, it is similar to the β-oxidation process, but the synthesis process is not a simple reversal of the β-oxidation process.

The similarities and differences between Hexadecanoic Acid synthesis and fatty acid β-oxidation can be summarized as follows:

① The places where the two pathways occur are different, β-oxidation is mainly carried out in mitochondria, and the de novo synthesis of saturated fatty acids is carried out in cytosol;

② Both pathways have an intermediate connected to the carrier, fatty acid is synthesized into ACP, and β-oxidized into CoA;

③ There are 4-step reactions in both pathways. Fatty acid synthesis is condensation, reduction, dehydration and reduction, and fatty acid β-oxidation is dehydrogenation, water addition, dehydrogenation and thiolysis. Although the two are reverse reactions from the chemical approach. However, their reaction processes are different, and the cofactors used are also different;

④ Both pathways have a raw material transport mechanism. In fatty acid synthesis, there is a tricarboxylic acid transport mechanism that transports acetyl CoA from mitochondria to cytoplasm. In degradation, there is a carnitine carrier system that transports fatty acyl CoA from cytoplasm to mitochondria;

⑤Both pathways are characterized by successive changes in fatty acid chains. In fatty acid synthesis, fatty acid chains obtain 2-carbon units and are successfully extended. In degradation, 2-carbon units in the form of acetyl CoA leave to achieve fatty acid chain shortening;

⑥Hexadecanoic Acid is synthesized from the methyl end of the molecule to the carboxyl end, and the degradation is in the opposite direction, with the departure of the carboxyl group as the first step.

⑦ The hydroxyester-based intermediate is D-configuration in fatty acid synthesis, but L-configuration in degradation;

⑧ Fatty acid synthesis is composed of a reduction pathway, which requires the participation of NADPH, and fatty acid decomposition is composed of an oxidation pathway, which requires the participation of FAD and NAD+;

⑨In animals, fatty acid synthase is a multifunctional enzyme composed of a polypeptide chain, and the decomposition of fatty acid is catalyzed by a variety of enzymes.

⑩β-oxidation is a process that produces a large amount of energy in addition to initial activation energy consumption. De novo synthesis of saturated fatty acids is an energy-intensive process.

The above are the important similarities and differences between fatty acid synthesis in cytosol and β-oxidation in mitochondria. In mitochondria, the synthesis reaction of Hexadecanoic Acid is the reverse process of β-oxidation reaction

Production Method of Hexadecanoic Acid

It exists widely in nature, and almost all oils contain palmitic acid components with varying contents. The content of palmitic acid in tallow tree oil, a specialty of our country, can be as high as 60%, while the content in palm oil of palm tree fruit is about 40%, but the content in vegetable oil is less than 2%. Hexadecanoic Acid is obtained by hydrolyzing tallow tree oil or palm oil, fractionating and pressing to separate unsaturated fatty acids, and then recrystallizing. Commercially available palmitic acid generally has a melting point of 57.5-62.5°C.

About Products:
If you need Hexadecanoic Acid, the cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Hexadecanoic Acid manufacturer and supplier, ZSpharmac will provide Hexadecanoic Acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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