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Glyoxylic Acid CAS 298-12-4

Molecular Formula: C2H2O3

Formula Weight: 74.04

ZSpharmac: Glyoxylic Acid Cosmetic Raw Material Suppliers

Product Name: Glyoxylic Acid
CAS No: 298-12-4
Purity: 99%

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Basic Info

Product Name:Glyoxylic Acid
Other Names:Glyoxylic Acid Solution
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Liquid
EINECS No.:206-058-5
Storage:Store Below +30°C.
Provide:Glyoxylic Acid MSDS;
Glyoxylic Acid COA

What is Glyoxylic Acid?

Glyoxylic acid, also known as acetic aldehyde and acetaldehyde, is a colorless liquid with an irritating and unique pungent odor. Its molecular formula is C2H4O2 and its structural formula is CH3CHO. It is a carboxylic acid derivative with a carbonyl group and a hydroxyl group.

Glyoxylic acid is mainly used as a chemical raw material and is widely used in organic synthesis, medicine, dyes, coatings and other fields. It is an important intermediate in the preparation of acetaldehyde, acetic acid and lactic acid. In addition, glyoxylic acid is also used as a solvent, preservative and raw material for the preparation of materials such as cellulose acetate.

Glyoxylic acid is usually produced by oxidation of ethylene, acetaldehyde or methanol, or by oxidation reactions during fermentation. In industry, glyoxylic acid is often used as one of the important raw materials of acetic acid to supply market demand.

Glyoxylic Acid Property

Melting point -93°C
Boiling point 111°C
density 1.33 g/mL at 20 °C
vapor pressure 14hPa at 19.85℃
refractive index n20/D 1.414
Fp 111°C
storage temp. Store below +30°C.
solubility Miscible with ethanol. Slightly miscible with ether and benzene. Immiscible with esters.
pka3.18(at 25℃)
form clear liquid
color Colorless to Light orange to Yellow
Water Solubility miscible


Glyoxylic Acid Uses

Glyoxylic acid is a key component in organic synthesis, serving as a crucial raw material for the preparation of various organic compounds such as anhydrides, esters, ethers, and amides. It finds widespread use in organic synthesis reactions, with applications including the synthesis of methyl esters and ethyl acetates.

In the pharmaceutical and medical fields, glyoxylic acid plays a vital role as an intermediate in drug synthesis. Its importance in the pharmaceutical industry is undeniable, as it can be used as a solvent or additive in drug formulations.

Coatings and Inks: Glyoxylic acid is widely used in the preparation of various inks and coatings. It has high volatility and good solubility and can be used as a diluent or plasticizer in inks and coatings.

Flavors and fragrances: Glyoxylic acid is a commonly used spice and fragrance ingredient and is widely used in food, cosmetics and daily chemical products. It can give the product a unique fragrance.

Food additive: Glyoxylic acid can be used as a food sourness regulator to increase the taste and taste of food. In the food processing industry, glyoxylic acid is commonly used in juices, jams, sauces and other foods.

Characteristics of Glyoxylic Acid

Structural features: Glyoxylic acid is a saturated carboxylic acid with a carboxyl group (-COOH) and an ester group (-OCH3) in its molecule. Because its molecule contains double bonds, it has certain reactivity.

Physical Properties: Glyoxylic acid is a colorless liquid with a pungent odor. It has good solubility and is soluble in water, alcohols and ether solvents.

Chemical properties: Glyoxylic acid is a common acidic substance that can undergo acid-base reactions. It can react with alcohols, amines, etc. to form esters, amides and other compounds, and can also undergo esterification, ester hydrolysis and other reactions.

Application fields: Glyoxylic acid is widely used in organic synthesis, flavors and fragrances, medicine, coatings, resins and other fields. It is an important raw material for the production of vinyl ether, acrylic acid and other compounds.

Application of Glyoxylic Acid in Cosmetics

Glyoxylic acid acts as a humectant. It has excellent moisturizing properties and can help maintain the skin’s moisture balance.

Glyoxylic acid can also be used as an antibacterial agent. It inhibits the growth of bacteria and fungi and can be used to maintain the freshness and stability of cosmetics.

Glyoxylic acid can be used as a pH adjuster. In some cosmetics, the pH value needs to be controlled to maintain the stability of the product, and glyoxylic acid can adjust the pH value.

Glyoxylic acid can also be used as an exfoliant. It can help remove aging keratinocytes from the skin surface, making the skin smoother and more delicate.


Pozdniakov, M.A., Zhuk, I.V., Lyapunova, M.V. et al. Glyoxylic acid: synthesis, isolation, and crystallization. Russ Chem Bull 68, 472–479 (2019).

Contact Us

As a company specializing in the production and supply of Glyoxylic Acid raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the Glyoxylic Acid raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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