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Glycerine Usp CAS 56-81-5

Molecular Formula: C3H8O3

Formula Weight: 92.09

ZSpharmac: Glycerine Usp Supplement

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Product Name: Glycerine Usp
CAS No: 56-81-5
Purity: 99%

Basic Info

Product Name:Glycerine Usp
Other Names:Glycerol
CAS:56-81-5
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Organic Chemical Raw Materials
Appearance:Colorless Viscous Liquid
EINECS No.:200-289-5
Storage:Store At +5°C to +30°C.
Provide:Glycerine Usp MSDS;
Glycerine Usp COA

What is Glycerine Usp ?

Glycerine Usp, also known as glycerol, pure glycerin is a colorless, odorless, sweet viscous liquid. The boiling point is 290 ° C, the melting point is 17.9 ° C, and the relative density is 1.2613.
Glycerine Usp is weakly acidic and can interact with alkaline hydroxides, such as copper hydroxide to generate bright blue Glycerine Usp copper (which can be used to identify polyols). Glycerine Usp reacts with nitric acid to form glycerol trinitrate, also known as nitroglycerin, which is a high explosive.Because Glycerine Usp is absorbent, it is often used as a hygroscopic and moisturizing agent in cosmetics, leather, tobacco, food and textiles. Glycerine Usp also has a laxative effect and can be used as an enema or as a suppository to treat constipation. Glycerol reacts with dibasic acids to obtain alkyd resins, which are widely used in paints and coatings. In nature, Glycerine Usp exists widely in the form of esters. For example, various animal and vegetable oils and fats are carboxylate esters of glycerol, and fatty acids and glycerol can be obtained by hydrolysis of oils and fats. At present, one of the main sources of Glycerine Usp is the by-product of the soap industry (hydrolysis of oils and fats under alkaline conditions), and the other source is the production of propylene from petroleum cracking gas.

Glycerine Usp Properties:

Melting point 20 °C(lit.)
Boiling point 290 °C
density 1.25 g/mL(lit.)
vapor density 3.1 (vs air)
vapor pressure <1 mm Hg ( 20 °C)
refractive index n20/D 1.474(lit.)
FEMA 2525 | GLYCEROL
Fp 320 °F
storage temp. Store at +5°C to +30°C.
solubility H2O: 5 M at 20 °C, clear, colorless
pka14.15(at 25℃)
form Viscous Liquid
color APHA: ≤10
Specific Gravity1.265 (15/15℃)1.262
OdorOdorless.
PH5.5-8 (25℃, 5M in H2O)
PH Range5.5 – 8
explosive limit2.6-11.3%(V)
Water Solubility >500 g/L (20 ºC)

 

Glycerine Usp Uses

  1. Glycerine Usp is used as water retention agent (for bread and cakes); carrier solvent (for flavors, pigments, water-insoluble preservatives, etc.); thickener (for beverages, wine preparation, etc.); plasticizer (candy) , desserts, meat products); sweeteners. EEC regulations can be used for alcoholic beverages, confectionery, cakes, coatings, meat and cheese coatings, non-alcoholic beverages, bakery products, gummies, gelatin desserts, etc.
  2. Glycerine Usp is an important basic organic raw material. It is widely used in industry, medicine and daily life. At present, there are about 1700 kinds of uses, mainly used in medicine, cosmetics, alkyd resin, tobacco, food, drinking acid resin, celluloid Slight and explosives, textile printing and dyeing and so on. Glycerol consumption in areas such as alkyd resins, cellulole and explosives is on a downward trend. But applications in medicine, cosmetics, and food will continue to grow.
  3. Glycerine Usp can form a nutrient source after hydrolysis in the body. 
  4. Glycerine Usp is used in gas chromatography fixatives.

Glycerine Usp Production Method

The industrial production methods of Glycerine Usp can be divided into two categories: the method using natural oils and fats as the raw material, and the obtained glycerin is commonly known as natural glycerin;
1. Production of natural Glycerine Usp Before 1984, Glycerine Usp was all recovered from the by-products of animal and vegetable fat soaps. Until now, natural oils and fats are still the main raw material for glycerin production. About 42% of the natural Glycerine Usp in the base comes from soap by-products, and 58% comes from fatty acid production. Saponification of oils and fats in the soap industry. The saponification reaction product is divided into two layers: the upper layer mainly contains fatty acid sodium salt (soap) and a small amount of glycerin, and the lower layer is waste lye, which is a dilute solution of glycerol containing salts and sodium hydroxide, generally containing 9-16% glycerol, inorganic salts 8-20%. Grease reaction. Glycerine water (also known as sweet water) obtained by oil hydrolysis has a higher Glycerine Usp content than soap-making waste liquor, about 14-20%, and inorganic salts 0-0.2%. In recent years, continuous high-pressure hydrolysis has been widely used, and the reaction does not use catalysts. Whether it is soap-making waste liquid or glycerin water obtained by oil hydrolysis, the amount of glycerin is not high, and they all contain various impurities. The production process of natural Glycerine Usp includes purification and concentration to obtain crude glycerin, and crude glycerin distillation and decolorization. The refining process of deodorization.

2. Production of Synthetic Glycerine Usp The various routes for synthesizing Glycerine Usp from propylene can be classified into two categories, namely chlorination and oxidation. Now the industry is still using propylene chlorination and propylene irregular acetic acid oxidation.
(1) Propylene chlorination method This is the most important production method in the synthesis of Glycerine Usp. It consists of four steps, namely, high temperature chlorination of propylene, hypochlorination of propylene chloride, saponification of dichlorohydrin and hydrolysis of epichlorohydrin. The hydrolysis of epichlorohydrin to glycerol is carried out at 150°C and 1.37MPa carbon dioxide pressure in an aqueous solution of 10% hydrogen peroxide and 1% sodium carbonate to generate a sodium chloride-containing glycerol aqueous solution with a glycerin content of 5-20%. After concentration, desalination and distillation, glycerol with a purity of more than 98% can be obtained.
(2) Propylene Peracetic Acid Oxidation Method Propylene and peracetic acid act to synthesize propylene oxide, and propylene oxide is isomerized to alkene to propanol. The latter reacts with peracetic acid to form glycidol (ie glycidol), which is finally hydrolyzed to Glycerine Usp.Acetaldehyde and oxygen are oxidized in gas phase. Under the conditions of normal pressure, 150-160 ° C, and contact time of 24 s, the conversion rate of acetaldehyde is 11%, and the selectivity of peracetic acid is 83%. The above-mentioned last two-step reactions are carried out continuously in a special-structured reactive distillation column. After the raw material allyl alcohol and the ethyl acetate solution containing peracetic acid are sent into the tower, the tower still is controlled at 60-70°C and 13-20kPa. The ethyl acetate solvent and water are evaporated from the top of the tower, and the tower still obtains an aqueous glycerin solution. This method has high selectivity and yield, uses peracetic acid as the oxidant, does not need a catalyst, has a faster reaction speed, and simplifies the process. At present, the output of natural Glycerine Usp and synthetic Glycerine Usp account for almost 50% each, and the propylene chlorination method accounts for about 80% of the output of Hezhi glycerin. my country’s natural Glycerine Usp accounts for more than 90% of the total output.

Analysis of Methylglyoxal Miel Content

Preparation of sodium periodate solution Take 60 g of sodium metapercarbonate (NaIO4), dissolve it in an aqueous solution containing 120 mL of 0.1 mol/L sulfur mash, and dilute to 1000 ml with water, without heating during dissolving. If the solution is not clear, filter through a sintered glass funnel. Store the solution in a light-shielded container with a glass stopper. Check the suitability of this test solution as follows. Pipette 10ml into a 250ml measuring bottle, make up to volume with water and mix. Dissolve about 550 mg of glycerol in 50 ml of water, and add 50 ml of the above dilute periodic acid solution with a pipette. In addition, 50ml of dilute periodate solution was taken and added to a flask containing 50ml of water, which was used as a control. Each solution was allowed to stand for 30min, 5ml of hydrochloric acid and 10ml of potassium iodide test solution (TS-192) were added to each, and the mixture was swirled and mixed. Let stand for another 5min, add 100ml of water, titrate with 0.1mol/L sodium thiosulfate, shake constantly, add a few drops of starch test solution (TS-235) at the end point, and then titrate to the end point. If the volume ratio of 0.1mol/L sodium thiosulfate consumed in the glycerol/periodate mixture and the blank test solution is between 0.750 and 0.765, Chemicalbook meets the applicable requirements. Operation Accurately weigh about 400mg of the sample, put it into a 600ml beaker, add 50ml of water to dilute, add a few drops of bromothymol test solution (TS-56), and acidify with 0.2mol/L sulfuric acid to a clear green or greenish yellow color. Neutralize with 0.05mol/L sodium hydroxide to a clear blue end point (no green). In addition, 50ml of water was used for neutralization according to the above operation, which was used as a blank test. Take 50ml of the above sodium periodate solution with a pipette, add it to each beaker, slowly shake to mix, cover with a watch glass, and place it in the dark or at room temperature (not more than 35°C) for 30min. Add 10ml of a mixture of equal volumes of ethylene glycol and water, and let stand for 30min. Each solution was diluted with water to about 300 ml. Using a pH meter pre-calibrated with a pH 4.0 phthalic acid (salt) standard buffer solution, the sample was titrated to pH 8.1 ± 0.1 with 0.1 mol/L sodium hydroxide, and the blank sample was titrated. to pH 6.5 ± 0.1. Each mL of 0.1mol/L sodium hydroxide solution is equivalent to 9.210mg of Glycerine Usp(C3H8O3) corrected by blank sample.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
  • Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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