Genistin CAS 529-59-9

Molecular Formula: C21H20O10

Formula Weight: 432.38

ZSpharmac: Genistin Cosmetic Raw Material Suppliers

Product Name: Genistin

CAS No: 529-59-9

Purity: 99%

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Basic Info

Product Name:	Genistin
Other Names:	Genistein
CAS:	529-59-9
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	Off-White Neat
EINECS No.:	610-921-5
Storage:	2-8°C
Provide:	Genistin MSDS； Genistin COA

What is Genistin?

Genistin is one of the energetic ingredients in soy isoflavones. It is the 7-glucoside of genistein, the energetic component of soy isoflavones. Genistin is used to reversely manage homocytisine as well as other tyrosine kinase inhibitors, which has the ability to boost insulin resistance, anti-diabetic results, hinder cancer cell task, hinder prostate cancer cells and antioxidant task. Its extraction provides new raw materials and practical additives for the food and also pharmaceutical markets.

Genistin Property

Melting point	254°C
Boiling point	256 °C
alpha	D21 -28° (c = 0.6 in 0.02N NaOH); D26 -21.4° (pyridine)
density	1.642±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 10 mg/mL
pka	6.12±0.20(Predicted)
form	neat
color	Off-white

Applications of Genistin

1. Used to prepare makeups with anti-aging results
CN201611046133.8 offers a structure with an anti-aging effect, so pertaining to increase the flexibility as well as radiance of the skin, along with reward prostatic hyperplasia, hypercholesterolemia, arteriosclerosis, impotence, as well as also menopause and postmenopause. Purpose of Signs and symptoms.

In order to attain the above item, today development adopts the adhering to technological service: a make-up with anti-aging effect, characterized in that the structure with anti-aging result contains daidzein, daidzein, genistin, genistein and also puerarin, Amongst them, the weight proportion of daidzein, daidzein, genistein, genistein as well as also puerarin is (3 * 104-7 * 104): (6-10): (0.8 * 104-1.5 * 104): (1 -3): (80-110). The make-up of the present moment innovation can enhance the versatility as well as appeal of the skin when utilized in the human body. In addition, the structure can be made use of for skin healthcare, breast care (consisting of breast flexibility, boob job, bust crease elimination) and also treatment of prostatic hyperplasia, hypercholesterolemia, arteriosclerosis, impotence and also menopausal as well as postmenopausal indications. Made use of in the manufacture of cosmetics, cosmeceuticals, medicinal items in addition to health care items, valuable foods, and also drinks.

2. Pharmaceutical make-ups for dealing with hyperlipidemia and atherosclerosis
CN201710312895.6 provides a pharmaceutical make-up with clear components, workable top quality, as well as likewise substantial performance for dealing with hyperlipidemia as well as atherosclerosis. The pharmaceutical cosmetics has active components, in addition to the energetic aspects are puerarin, daidzein, genistin, daidzein, callisoflavone glucoside, astragalus saponin II, astragaloside IV, formononetin, in addition to morin A. A mix of 2 or more of morin, scopolamine, mulberry C, 1-deoxynojirimycin, kudzu polysaccharide, astragalus polysaccharide as well as also mulberry bark polysaccharide. The pharmaceutical structure can reduce the place of fatty plaque in the aorta of the atherosclerosis model apoE-/- transgenic computer system mice, has the result of controling hyperlipidemia in computer mice, as well as also can take care of hyperlipidemia as well as also atherosclerosis.

Genistin Preparation

An approach for removing genistin from Trichosanthes grandiflora; the raw products of this approach are plentiful as well as very easy to acquire, the procedure is basic as well as possible, there is much less contamination, the cycle is short, the product obtained has high purity as well as is easy to prepare widespread. Includes the adhering to steps:

( 1) Slice the raw product Big Fallen leave Qianjin, as well as use an ethanol liquid remedy with a concentration of 50 to 70% to reflux as well as extract for 1.5 to 5 hours to get the essence;

( 2) Concentrate the essence acquired in step (1) as well as put it on a chromatographic column. The fixed stage in the chromatographic column is a macroporous adsorption material; wash with an ethanol-water option with a quantity proportion of 15 to 25:85 to 75 as the mobile stage. Get rid of and also collect the eluate;

( 3) Concentrate the eluate gotten symphonious (2) to a thick remove, include ethanol consisting of 2 to 3% antarctic acetic acid, completely liquify it, allow it stand, filter to eliminate insoluble matter, recrystallize the filtrate, and also clean the crystals with ethanol, vacuum drying to obtain genistin.

This technique can obtain high-purity genistin; without the requirement for numerous splittings up and also purifications, just one macroporous adsorption material column chromatography is needed to acquire high-purity genistin. The method is basic to run and also has excellent reproducibility; just water, ethanol and also A small amount of antarctic acetic acid, conserving reagents, low cost, risk-free and also environmentally friendly; really appropriate for large, industrial manufacturing.

How to Detect Genistin

Soy isoflavones include a selection of members with extremely diverse chemical frameworks as well as organic features, such as daidzein, mangiferin, daidzin, and genistin. The primary part of soy isoflavones removed from soybeans is genistin. Genistin is just one of the active ingredients of soy isoflavones and also is structurally a phytoestrogen. Study has actually located that genistein can not be straight soaked up by the body. Rather, it is hydrolyzed by enzymes in intestinal microorganisms and also soaked up in the form of genistein to apply biological task. Genistein is more active than daidzein in many elements.

CN201711287750.1 offers a method for discovering genistin in honey vinegar black beans. This approach makes use of methanol ultrasound-assisted removal approach to essence genistin from honey vinegar black beans, and also uses ultra-high performance fluid chromatography to find its web content. It contains honey vinegar black bean essence prep work, conventional service prep work, and also example remedy preparation. and also ultra-performance liquid chromatography detection and other steps to get the genistin web content in honey vinegar black beans. Includes the complying with specific steps:

S1. Prep work of honey vinegar black bean essence: squash the dried honey vinegar black beans, filter to get honey vinegar black bean powder, add methanol solution An as well as ultrasonic, take the supernatant after centrifugation, focus the supernatant, and utilize it with methanol Weaken service B to a continuous volume to acquire genistin remove;

S2. Prep work of genistin conventional option: Thin down the genistin criterion to quantity with methanol remedy C, and also conduct ultrasonic treatment to prepare genistin common mommy remedy. Dilute the genistin conventional mommy service with methanol solution C to prepare genistin. Glycoside common option;

S3. Prep work of example solution: Dilute the genistin remove gotten symphonious S1 with methanol remedy C, pass it through the filter membrane layer, as well as store it for later usage;

S4. Ultra-high performance fluid chromatography detection: Detect the material of the sample gotten symphonious S3, as well as utilize the mobile stage to examine pure methanol, glacial acetic acid and also water to identify the content of genistin in the honey vinegar black bean product.

About Products:
If you need Genistin, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Genistin manufacturer and supplier, our company, ZSpharmac, will provide Genistin raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.