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Gamma Polyglutamic Acid CAS 25513-46-6

Molecular Formula: C5H9NO4

Formula Weight: 147.13

ZSpharmac: Gamma  Polyglutamic Acid Supplier

Product Name: Gamma Polyglutamic Acid
CAS No: 25513-46-6
Purity: 99%

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Basic Info

Product Name:Gamma Polyglutamic Acid
Other Names:Polyglutamic Acid
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Colorless Viscous Liquid
EINECS No.:200-293-7
Provide:Gamma Polyglutamic Acid MSDS;
Gamma Polyglutamic Acid COA

What is Gamma Polyglutamic Acid?

Polyglutamic acid (γ-PGA), similarly referred to as natto periodontal tissue along with polyglutamic acid, is a water-soluble, green, safe biopolymer produced by microbial fermentation. γ-PGA polyglutamic acid is a sticky product that was first uncovered in “natto” – fermented beans. γ-PGA polyglutamic acid is an unique anionic natural polymer, which corresponds kind developed by amide link in between α-amino team (α-amino) and likewise γ-carboxyl team (γ-caboxyl). Normally utilized for moisturizing, bleaching, anti-bacterial, as well as boosting skin wellness.

Polyglutamic acid was first discovered to exist in Japanese natto food (fermented tiny soybeans) in the high-viscosity picture. It is abbreviated as γ-PGA in China. Biopolymerization using liquid fermentation to create decomposable high-molecular amino acid polymers.

Effects of Gamma Polyglutamic Acid on Plants

What is the typical mechanism of Gamma Polyglutamic Acid to advertise plant growth? To put it merely, why does polyglutamic acid have such an outstanding impact? Because it has the impact of trinity of macromolecule, middle molecule as well as additionally little particle at the same time.

In the preliminary phase, to begin with, it has excellent water retention, likewise called water retention as well as fertilizer, which incorporates fertilizer as well as likewise water, reduces water loss, along with withstands dry spell; according to its molecular framework, it has a superb feature of chelating micronutrient; It belongs to the microbial training course itself, so it can enhance the dirt microbial framework.

The 2nd phase, which is furthermore a very essential stage, is carried out as a biostimulant as well as signaling product. It can considerably boost the performance of plant photosynthesis; furthermore, it can up-regulate genetics linked to plant stress and anxiety resistance as well as additionally boost anxiousness resistance. To place it merely, the even worse the setting, the much better the outcome. At this time, its resistance to misery will certainly be used the extreme.

Finally the 3rd stage ends up being the amino acid which is taken in straight.

Gamma Polyglutamic Acid reduces the material of malondialdehyde, enhances the build-up of proline, boosts the activity of antioxidant enzymes, and also can boost the ability of plants to take on cold as well as warm.

Gamma Polyglutamic Acid controls plant physical changes with special signaling courses, improves the task of proline as well as stress-related enzymes, and also reduces the web content of malondialdehyde, as a result boosting its ability to withstand minimized temperature level and also high temperature.

Gamma Polyglutamic Acid enhances the accumulation of proline in plant cells by turning on the proline synthesis path, therefore boosting its resistance to acidic and likewise alkaline anxieties in dirt. It reveals a very high level of anti-acidification and additionally anti-salt-alkali capability.


The effect of Gamma Polyglutamic Acid on the Skin

Gamma Polyglutamic Acid is generally utilized as a cream as well as skin conditioner in cosmetics as well as skin treatment items. The risk aspect is 1. It is reasonably secure as well as can be utilized with confidence. It usually has no result on expectant ladies. Polyglutamic acid is not acne-causing.

Gamma Polyglutamic Acid can promote the activity of fibroblasts, and has skin revitalizing effect, and can be used in anti-aging and anti-wrinkle cosmetics; the promotion of fibroblast activity by polyglutamic acid with larger molecular weight is not as good as that of small molecular weight ones, but its It is superior to small molecular weight products in terms of stable foam, moisturizing ability, and adsorption on hair. It can be used in hair water to resist static electricity and make hair soft. Polyglutamic acid has the effect of whitening skin.

Gamma Polyglutamic Acid for Cosmetic and Agricultural Applications

Cosmetic: A new method for extracting Gamma Polyglutamic Acid, that is, adding lysozyme and protease in proportion to the fermented liquid at a certain pH and temperature, acting for a certain period of time to remove the bacteria in the fermented liquid, then adding an appropriate amount of ethanol to make an emulsion and Precipitate the glue residue, remove the glue residue by centrifugation, then add an appropriate amount of sodium salt to precipitate the colloid and separate impurities such as pigments and salts at the same time, rehydrate and dissolve the colloid, further desalt, pigment and other small molecule impurities through ultrafiltration concentration, and then use the ultrafiltration concentrate Add ethanol to precipitate the colloid, replace the high alcohol several times to reduce the viscosity of the colloid, centrifuge and separate the ethanol, and vacuum dry or freeze-dry the product γ-PGA. The invention has the advantages of simple extraction process, low production cost and good product quality.

Agriculture: γ-polyglutamic acid γ-PGA can be made use of as a nutrient for plant manufacturing increase
1. γ-polyglutamic acid γ-PGAHydrogel along with γ-PGA have unbelievably hydrophilicity in addition to water retention capability
When it is flooded in the dirt, a flick will certainly be based on the area of the root hairs of the plant, which not just has the feature of securing the beginning hairs, yet furthermore is the most reliable shipment system for the nutrients and water in the dirt to be in close contact with the root hairs, and can efficiently elevate the plant food manufacturing. dissolution, storage space, transportation as well as absorption. Protect against the rainfall of sulfate, phosphate, oxalate and also steel elements, to see to it that plants can more effectively absorb phosphorus, calcium, magnesium along with trace element in the dirt. Promote the advancement of crop beginning system as well as enhance condition resistance.
2. γ-polyglutamic acid γ-PGAHydrogel and also γ-PGA equilibrium dust pH.
It has exceptional buffering capacity for acid as well as antacids, which can properly balance the pH well worth of the dust and additionally avoid the acidic dirt brought on by lasting use chemical plant foods.
3. γ-polyglutamic acid γ-PGA Hydrogel as well as γ-PGA can be integrated to precipitate toxic heavy metals.
It has exceptional chelating result on dangerous heavy metals such as Pb +2, Cu +2, Cd +2, Cr +3, Al +3, As +4, and so on 4. γ-polyglutamic acid γ-PGAHydrogel and also γ-PGA can boost plant resistance to disease and also difficulty.
Integrating plant nutrients, water-active elements in the soil, can improve resistance to signs induced by soil-borne plant microbes.
5. Advertise producing increase.
It can swiftly enhance the manufacturing of farming things such as tea, melons as well as additionally fruits, as well as also veggies, as well as the manufacturing boost can get to 10-20%. Polyglutamic acid is a homopolyamino acid formed by linking glutamic acid monomers with amide bonds. It is environment-friendly, exceptionally strong chelating adsorption capacity, very high water absorption along with hydrating ability in addition to fantastic biodegradability. The synergistic plant food included with Gamma Polyglutamic Acid has significant water retention, plant food retention, return boost, stress resistance and remodelling of plant top quality 5 application results. Polyglutamic acid can be split right into 2 types according to the product, various plant food dose kinds in addition to various other indications, and likewise the water preparation job can be separated right into 1001-1007 7 types, and also the powder can be divided into 2001-2003 3 dosage types. All type of dose kinds apply to the manufacturing of chlorine-based, sulfur-based, urea-based, and nitro-based fertilizers, as well as additionally apply to drum, spraying, high tower, in addition to extrusion granulation!

Features of Gamma Polyglutamic Acid

Since there are a large number of free carboxyl groups, amino groups and carbonyl groups on the molecular chain of γ-PGA, there are three functional groups with hydration ability, among which, the ability of carboxyl groups is more obvious, and there are a large number of hydrogen bonds between γ-PGA chains, so that γ-PGA has super water-retaining and water-locking properties. It also has the ability to chelate metal ions, has good antibacterial properties, film-forming properties, strong smoothness, and sustained release capabilities, making it ideal for use in cosmetics to enhance and prolong moisturizing effects. In addition, γ-PGA also has synergistic vitamin C antioxidant effect and whitening effect of inhibiting skin tyrosinase activity (about 50% of kojic acid).

About Products:
If you need Gamma Polyglutamic Acid, a cosmetic raw material, please contact our service staff directly, and we will provide you with high-quality products at the best price.
As an experienced Gamma Polyglutamic Acid manufacturer and supplier, ZSpharmac will provide Gamma Polyglutamic Acid raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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