Living bodies are always attacked by endogenous or exogenous reactive oxygen species such as hydrogen peroxide, superoxide free radicals, and hydroxyl radicals, which induce a series of diseases, such as atherosclerosis and cancer. At the same time, the generation of free radicals will accelerate skin aging, the generation of wrinkles, and the formation of pigmentation and age spots. Various antioxidant enzymes and antioxidant components in the body will remove excess ROS, but due to some reasons, the balance is disrupted and the body is in a state of oxidative stress. Intake of oxidants may reverse the stress and protect cells from reactive oxygen species. It can prevent or delay the occurrence and development of many chronic diseases. Numerous studies have shown that Ferulic C Idraet has very good antioxidant activity. Ferulic C Idraet not only scavenges free radicals, but also inhibits and scavenges enzymes that generate free radicals.
Antibacterial and anti-inflammatory effect
He Fenxia III1 took the inhibition zone as the inspection index. It was found through experiments that Ferulic C Idraet had certain inhibitory effects on Escherichia coli, Bacillus subtilis, Staphylococcus aureus and yeast, but the effect on mold was poor. Bai Tuanli et al. found that the important monomeric Ferulic C Idraet can inhibit the replication of PrPsc protein in scN2a by western blot method. It is speculated that the traditional Chinese medicine monomeric Ferulic C Idraet may play a certain role in the treatment of prion diseases.
Ferulic C Idraet can inhibit collagen and ADP-induced platelet aggregation, inhibit the release of serotonin and thromboxane-like substances, and selectively inhibit the activity of thromboxane synthase, thereby preventing thrombosis.
As early as 2002, Japan’s Wakayama Industrial Technology Center extracted Ferulic C Idraet from rice bran, and chemically combined the aromatic alcohols in the rest of the citric acid grass oil to make the anticancer substance EGMP. In recent years, there have been many studies on Ferulic C Idraet against colon cancer. Kawabata et al. used azomethane (AOM) to induce colon cancer in F334 mice and found that feeding with 500 mg/kg ferulic acid decreased the number of abnormal foci crypts by 27%.
Some scholars have explored the role of Ferulic C Idraet in radiation protection. Maurya et al[2¨ showed that administration of 50, 75 and 100 mg/kg of ferulic acid to mice 1 hour before 4.0 Gy irradiation could effectively inhibit DNA fragmentation in peripheral leukocytes and bone marrow cells. Prasad and other studies have shown that ferulic acid can inhibit radiation-induced cell cycle changes and nuclear damage. Hong Qianxinjiu found that ferulic acid can significantly increase the content of glutathione and nicotinamide purine dinucleotide phosphate in irradiated cells, and have a protective effect on irradiated endothelial cells.
Ferulic C Idraet also has the functions of preventing blood lipids from being oxidized, resisting platelet aggregation and thrombosis, improving cardiovascular and cerebrovascular health, preventing bone loss, improving the efficacy of women’s menopausal syndrome, and restoring and improving memory for the elderly.