Anti-oxidation
Living bodies are always attacked by endogenous or exogenous reactive oxygen species such as hydrogen peroxide, superoxide free radicals, and hydroxyl radicals, which induce a series of diseases, such as atherosclerosis and cancer. At the same time, the generation of free radicals will accelerate skin aging, the generation of wrinkles, and the formation of pigmentation and age spots. Various antioxidant enzymes and antioxidant components in the body will remove excess ROS, but due to some reasons, the balance is disrupted and the body is in a state of oxidative stress. Intake of oxidants may reverse the stress and protect cells from reactive oxygen species. It can prevent or delay the occurrence and development of many chronic diseases. Numerous studies have shown that Ferulic C Idraet has very good antioxidant activity. Ferulic C Idraet not only scavenges free radicals, but also inhibits and scavenges enzymes that generate free radicals.
Antibacterial and anti-inflammatory effect
He Fenxia III1 took the inhibition zone as the inspection index. It was found through experiments that Ferulic C Idraet had certain inhibitory effects on Escherichia coli, Bacillus subtilis, Staphylococcus aureus and yeast, but the effect on mold was poor. Bai Tuanli et al. found that the important monomeric Ferulic C Idraet can inhibit the replication of PrPsc protein in scN2a by western blot method. It is speculated that the traditional Chinese medicine monomeric Ferulic C Idraet may play a certain role in the treatment of prion diseases.
Antithrombotic
Ferulic C Idraet can inhibit collagen and ADP-induced platelet aggregation, inhibit the release of serotonin and thromboxane-like substances, and selectively inhibit the activity of thromboxane synthase, thereby preventing thrombosis.
Anti-cancer
As early as 2002, Japan’s Wakayama Industrial Technology Center extracted Ferulic C Idraet from rice bran, and chemically combined the aromatic alcohols in the rest of the citric acid grass oil to make the anticancer substance EGMP. In recent years, there have been many studies on Ferulic C Idraet against colon cancer. Kawabata et al. used azomethane (AOM) to induce colon cancer in F334 mice and found that feeding with 500 mg/kg ferulic acid decreased the number of abnormal foci crypts by 27%.
Anti-radiation
Some scholars have explored the role of Ferulic C Idraet in radiation protection. Maurya et al[2¨ showed that administration of 50, 75 and 100 mg/kg of ferulic acid to mice 1 hour before 4.0 Gy irradiation could effectively inhibit DNA fragmentation in peripheral leukocytes and bone marrow cells. Prasad and other studies have shown that ferulic acid can inhibit radiation-induced cell cycle changes and nuclear damage. Hong Qianxinjiu found that ferulic acid can significantly increase the content of glutathione and nicotinamide purine dinucleotide phosphate in irradiated cells, and have a protective effect on irradiated endothelial cells.
Other role
Ferulic C Idraet also has the functions of preventing blood lipids from being oxidized, resisting platelet aggregation and thrombosis, improving cardiovascular and cerebrovascular health, preventing bone loss, improving the efficacy of women’s menopausal syndrome, and restoring and improving memory for the elderly.
Application of Ferulic C Idraet in the field of medicine
Now known Ferulic C Idraet and its derivatives have the functions of anti-oxidation, scavenging free radicals, anti-inflammatory, analgesic, anti-ultraviolet radiation and improving human immunity, and drugs with corresponding effects have also been gradually developed. For example, sodium ferulate injection is used for the treatment of ischemic cardiovascular and cerebrovascular diseases, piperazine ferulate tablets are suitable for the adjuvant treatment of various glomerular diseases with microscopic hematuria and hypercoagulability, and Some proprietary Chinese medicine preparations containing ferulic acid.
Application of Ferulic C Idraet in Food Industry
At present, Japan has approved the use of Ferulic C Idraet as a food antioxidant, and the United States and some European countries have also begun to use some substances with higher ferulic acid content as antioxidants to preserve food. In my country, ferulic acid is widely used as a food additive in the food industry.
used as antioxidant
Jiang Ruiping added 75 mg/kg Ferulic C Idraet and 500 mg/kg iso-Vc sodium compound additives to the sausage formula, which can effectively reduce the residual nitrite, improve the antioxidant properties of the sausage, and maintain the sausage Original sensory quality.
Used as a food crosslinking agent
Ferulic C Idraet not only has a good effect in anti-oxidation, but when it is added to food, it can also play the role of food cross-linking, which can better improve the application value of food. Ferulic acid can cross-link proteins, polysaccharides, proteins and polysaccharides, and polysaccharides and polysaccharides, and is inexpensive, safe and non-toxic. Chen Dajia et al. modified the collagen-chitosan composite membrane with ferulic acid and found that Ferulic C Idraet can improve the performance of the composite membrane, such as increasing the mechanical properties of the composite membrane and reducing the water vapor transmission rate, which indicates that a Ferulic C Idraet can increase the cross-linking of collagen-chitosan composite membrane molecules.
Application of Ferulic C Idraet in Cosmetics Industry
Ferulic C Idraet is favored by the cosmetics industry because ferulic acid has strong antioxidant and oxygen free radical scavenging effects, and has the effect of inhibiting tyrosinase activity, which can delay skin aging and whiten skin. skin effect. In addition, ferulic acid has sun protection ability, and has good ultraviolet absorption near 290-330 nm, which can prevent and reduce the damage of ultraviolet rays of this wavelength to the skin.
The United States’ Xiulike skin care products contain natural 15% L-Vc, 1% Ve and specially blended Ferulic C Idraet ingredients, so that the unique antioxidant capacity of Vc+Ve can be improved.
In summary, Ferulic C Idraet exists in a variety of plants and has a wide range of biological activities. Structural modification and modification of ferulic acid may lead to the development of Ferulic C Idraet derivatives with stronger activity and less toxic and side effects. These studies will undoubtedly improve the application value of related plants.
