Zhishang Chemical

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Zhishang Chemical

Ethyl Cellulose CAS 9004-57-3

Molecular Formula: C23H24N6O4

Formula Weight: 448.47446

ZSpharmac: Ethyl Cellulose Supplement

Product Name: Ethyl Cellulose
CAS No: 9004-57-3
Purity: 99%

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Basic Info

Product Name:Ethyl Cellulose
Other Names:Cellulose Ether
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White to Slightly Yellow Powder
EINECS No.:618-384-9
Provide:Ethyl Cellulose MSDS;
Ethyl Cellulose COA

What is Ethyl Cellulose?

Ethyl cellulose (or ethyl cellulose) is a by-product of cellulose in which several of the hydroxyl teams on the duplicating sugar systems are converted to ether groups. The quantity of ethyl might vary by manufacturer. White to light gray fluid paste, thermoplastic. It is unsteady to warmth, tarnishes at high temperature (240 ° C) as well as sheds its initial physical and chemical homes. Thickness should be defined for industrial grade items. The family member thickness is 1.07 ~ 1.18, the refractive index is 1.47, as well as the softening point is 100 ~ 130 ℃. It can form a tough movie and also can still maintain versatility at reduced temperature level. Can be blended with resin, wax, oil, etc. Steady to antacid and also water down acids. The softening factor as well as hygroscopicity decreased with the rise of ethoxy material. The ethoxy material of standard products is 47% to 48%. Virtually insoluble in water, glycerol and propylene glycol, however soluble in some natural solvents to differing degrees (depending upon the ethoxy web content). Ethyl cellulose with an ethoxy content of less than 46% to 48% is conveniently soluble in a mix of tetrahydrofuran, methyl acetate, chloroform as well as aromatic hydrocarbon-ethanol. Those with an ethoxy content greater than 46% to 48% are conveniently soluble in ethanol, methanol, toluene, chloroform and also ethyl acetate. The base test of the 5% suspension was neutral.

Ethyl Cellulose Property

Melting point 240-255 °C
density 1.14 g/mL at 25 °C (lit.)
refractive index n20/D 1.47(lit.)
storage temp. 2-8°C
solubility esters, aromatic hydrocarbons, alcohols and ketones: soluble
form powder
color White to slightly yellow
Specific Gravity1.14
Water Solubility insoluble


Ethyl Cellulose Uses

  1. Ethyl cellulose is made use of for tablet compression (mostly for vitamins and not natural salts); binder for vitamin powder; filler; dilution of pigments as well as various other artificial additive.
  2. Ethyl cellulose is made use of as a binder and also cable paint.
  3. Ethyl cellulose is used in inks, finishes, adhesives, medicine, cosmetics and also food areas, along with fillers, adhesives, etc.
  4. Ethyl cellulose is made use of in large quantities in coverings. It can additionally be made use of as a basic material for strong lubricants for steel workpiece stamping. In microcircuit printing, ethyl cellulose is utilized as an automobile. In the radio industry, it is made use of as a high-grade insulating material, and as an unique film in protective coverings, such as the cladding of rocket propellants. It can be utilized as hot-melt adhesives as well as finishings for cables, paper, textiles, and so on, along with insulation for extrusion lines and also sturdiness boosters for plastics. It can also be utilized as a pigment grinding base, for printing inks, for molding plastic powder, for explosive fuzes, as well as for vitamin solutions. Utilized as a peelable covering to protect metal parts from rust and damages prior to utilize, and as a peelable finishing to shield breakable glass wares. In adhesives, fabrics and also fibers, medicine and also food, as well as other industries, there are many usages. Industrial quality ethyl cellulose is utilized in layers (gel kind finishings, warm thaw coverings), inks (display printing inks, gravure inks), adhesives, pigment pastes, etc. Advanced products are utilized in medicine, cosmetics and food, such as pharmaceutical tablet packaging products, binders for long-acting prep work, and so on.

Ethyl Cellulose Identification Test

Solubility Almost insoluble in water, glycerol and propylene glycol. However, it is soluble in some organic solvents to varying degrees (depending on the ethoxy content), and those with an ethoxy content less than 46% to 48% are easily soluble in tetrahydrofuran, methyl acetate, chloroform and aromatic hydrocarbon-ethanol mixture; Those with oxygen content greater than the above are easily soluble in ethanol, methanol, toluene, chloroform and ethyl acetate. Determined by OT-42 method.

Take 5g of sample and dissolve it in 95g of toluene-ethanol mixture (80:20, W/W). The solution should be stable, transparent and slightly yellow. Take a few milliliters of the solution and transfer it to a test tube or glass plate, let it evaporate, and it will appear cloudy and thick successively until the residue is a transparent film. The film is flammable.

Ethyl Cellulose in Vitro and Ex Vivo

Transdermal drug distribution systems (TDDS) have become ingenious as well as appealing drug delivery approaches made for dermal application for systemic activity. TDDS conquers the drawbacks associated with oral and parenteral courses of administration. The existing study intended to create, examine, as well as optimize methotrexate (MTX)-filled transdermal patches with varying focus of ethylcellulose (EC) as well as hydroxypropylmethylcellulose (HPMC), for the topical management of psoriasis. Artificial insemination launch and in vitro permeation research studies were performed on the created patches. Numerous formulations (F1-F9) were created making use of various concentrations of HPMC as well as EC. The F1 formula with a 1:1 polymer focus proportion was utilized as a control solution. ATR-FTIR analysis was performed to study drug-polymer interactions as well as found that the medicine and polymer worked with each other. The physicochemical criteria, artificial insemination launch as well as in vitro diffusion residential properties of the developed patches were further explored. Different criteria such as surface pH, physical look, density, weight uniformity, percent dampness uptake, percent water loss, folding resistance, skin irritability, security, and drug web content uniformity were explored. From hydrophilic mixtures, a direct result of thickness on medicine launch was observed. Throughout all formulated patches, the F5 solution exhibited 82.71% medication launch in a sustained-release fashion and complied with an abnormal non-Fickian spread. The leaks in the structure information for the F5 formulation shows about 36. The collective medication infiltration portion is 55%. The skin showed high retention (15.1%) to the F5 formula. Stability research studies have shown that all prepared formulas have excellent stability over a duration of 180 days. Therefore, it was concluded from this research study that methotrexate transdermal spots with EC and also HPMC as polymers at different concentrations were well matched for TDDS and boosted individual compliance with topical administration of psoriasis.

About Products:
If you need Ethyl Cellulose, a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Ethyl Cellulose manufacturer and supplier, ZSpharmac will provide Ethyl Cellulose raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, and customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

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