Ethyl 2-Oxopropanoate CAS 617-35-6

Molecular Formula: C5H8O3

Formula Weight: 116.12

ZSpharmac: Ethyl 2-Oxopropanoate Cosmetic Raw Material Suppliers

Product Name: Ethyl 2-Oxopropanoate

CAS No: 617-35-6

Purity: 99%

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Basic Info

Product Name:	Ethyl 2-Oxopropanoate
Other Names:	Ethyl Pyruvate
CAS:	617-35-6
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	Clear Pale Yellow Liquid
EINECS No.:	210-511-2
Storage:	Store at +2°C to +8°C.
Provide:	Ethyl 2-Oxopropanoate MSDS； Ethyl 2-Oxopropanoate COA

What is Ethyl 2-Oxopropanoate?

Ethyl pyruvate (English ethylpyruvate), the molecular formula is CH3COCOOC2H5, likewise known as ethyl 2-oxopropionate. It is a colorless and also transparent fluid at room temperature. It has a fresh, pleasant floral and fruity scent and can be used in flavors such as apples, citrus, and chocolate. in the preparation. It is an exceptionally crucial natural synthesis intermediate as well as is made use of in medication (artificial thiimido medications), chemicals (herbicides and thiimido fungicides produced by DuPont), food (can be made use of as chemicals, chemicals, etc), cosmetics It has a variety of uses in other markets.
Ethyl 2-Oxopropanoate has a great result on hindering the formation of tyrosinase in the skin, so it can prevent the development of epidermal melanin and lighten the skin. It can also be contributed to air fresheners as an effective active ingredient, which can efficiently get rid of ammonia and also methyl mercaptan airborne, and has a fresh and all-natural odor. Ethyl 2-Oxopropanoate has superior performance in creating heterocyclic substances and is an irreplaceable resources and also intermediate in chemical synthesis. It is widely made use of in the synthesis of fungicides and also herbicides. Oxazolone derivatives manufactured from ethyl pyruvate It is likewise a great fungicide, which can successfully inhibit and eliminate fungis at a focus of 5.0 × 10-4.
Pyruvate is the major basic material for the manufacturing of tryptophan, phenylalanine, protein sugar and also vitamin B. It is the raw material for the biosynthesis of L-dopa (dopa is made use of to deal with Parkinson’s disorder) as well as the beginning agent for ethylene polymers., is additionally a basic material for preparing grain protective representatives. A very efficient herbicide was synthesized from pyruvic acid. The herbicide has outstanding selectivity and also works in getting rid of weeds such as sedge as well as setaria, and is risk-free for crops. As a feed and food additive, it has great disinfectant and also conservation features. Currently, a percentage of it is utilized in the conservation of feed as well as fruit white wine in China. Ethyl pyruvate itself has a special scent as well as can be used in flavors and fragrances. It is likewise a crucial resources for synthetic materials as well as plastics. Pyruvate products can additionally be utilized as special solvents in digital products, and also foreign demand for this application is boosting rapidly.

Ethyl 2-Oxopropanoate Property

Melting point	-58 °C
Boiling point	144 °C (lit.)
density	1.045 g/mL at 25 °C (lit.)
vapor pressure	2.36hPa at 25℃
refractive index	n20/D 1.404(lit.)
Fp	114 °F
storage temp.	Store at +2°C to +8°C.
solubility	10g/l
form	Liquid
color	Clear pale yellow
Odor	at 10.00 % in dipropylene glycol. ether fruity sweet sharp rum vegetable caramel
Odor Type	ethereal
Water Solubility	Miscible with water, ethanol and ether.

Ethyl 2-Oxopropanoate Uses

Antibacterial Impact
Ethyl 2-Oxopropanoate has a great result on preventing the development of tyrosinase in the skin, so it can stop the formation of skin melanin and whiten the skin. It can likewise be included in air fresheners as a reliable energetic component, which can effectively eliminate ammonia and also methyl mercaptan airborne, and also has a fresh as well as natural scent. Ethyl pyruvate has exceptional performance in developing heterocyclic compounds and is an irreplaceable basic material as well as intermediate in chemical synthesis. It is widely utilized in the synthesis of fungicides as well as herbicides. Oxazolone derivatives synthesized from ethyl pyruvate It is additionally a good fungicide, which can effectively prevent as well as eliminate fungis at a focus of 5.0 × 10-4.

Industrial Applications
Ethyl 2-Oxopropanoate is the main raw material for the production of tryptophan, phenylalanine, healthy protein sugar and vitamin B. It is the raw material for the biosynthesis of L-dopa (dopa is used to treat Parkinson’s syndrome) and the origin of ethylene polymers. It is a starting agent and also a resources for preparing grain safety representatives. An extremely effective herbicide was synthesized from pyruvic acid. The herbicide has superb selectivity as well as is effective in getting rid of weeds such as sedge as well as setaria, and is safe for plants. As a feed and artificial additive, it has great disinfectant and preservation functions. Presently, a percentage of it is used in the conservation of feed and fruit white wine in China. Ethyl pyruvate itself has an unique fragrance and also can be made use of in flavors and scents. It is likewise an important basic material for synthetic materials as well as plastics. Pyruvate products can likewise be used as special solvents in digital materials, and also international need for this application is enhancing quickly.

Pharmaceutical/Cosmetic Applications
Ethyl 2-Oxopropanoate can be used to manufacture the pharmaceutical indoxolol as well as the pesticide thiabendazole. It is likewise an important pharmaceutical and chemical intermediate, extensively made use of in medication, chemicals, flavors and scents, preservative, air fresheners, fine chemicals and other markets. It can be made use of to manufacture medicines such as cardio dilators; it can additionally be used in cosmetics for lightening and nourishing the skin, which can promote skin injury recovery and also protect against as well as deal with skin diseases defined by cracking, peeling off and also scaly; it can be made use of as a component in air fresheners. A highly efficient energetic ingredient that can successfully get rid of ammonia and also methyl mercaptan airborne. It has a special scent, so it can be made use of in tastes and fragrances. It is additionally an important resources for synthetic materials as well as plastics.

Ethyl 2-Oxopropanoate Production Methods

Its preparation methods include the following. Gas-phase oxidation of ethyl lactate. Gas-phase oxidation of ethyl lactate is carried out in the presence of a driver. MoO3 as a driver shows greater selectivity than various other steel oxides. On top of that, the binary oxide driver has molybdenum oxides such as Fe2O3-MoO3 as well as TeO2-MoO3 has high selectivity for the synthesis of Ethyl 2-Oxopropanoate (temperature 300 ° C, selectivity goes beyond 90%). If SnO2-MoO3 is made use of as a driver, it can be accomplished at a reduced temperature level of 250 ° C. The SnO2-MoO3 stimulant can likewise be used as a catalyst for the liquid stage oxidation of lactate ester. The reaction temperature is 130 ° C as well as the reaction time is 3 hours. The conversion price of ethyl lactate is 38.4% and the selectivity is 98.9% to generate Ethyl 2-Oxopropanoate. Liquid-phase oxidation of ethyl lactate: Ethyl lactate is oxidized in the visibility of a percentage of bromine as a driver, and H2O2 is utilized as the oxidant for oxidation. For instance, 50% H2O2 is included dropwise to dichloromethane consisting of ethyl lactate and bromine that is stirred and also illuminated. In the remedy, the reaction temperature level is 25 ° C, and also the H2O2 dropwise enhancement time has to do with 1.5 h. After the dropwise addition, the response is proceeded for 3h. The service is reduced the effects of with NaHCO3 as well as cleaned with Na2SO3 service to destroy as well as get rid of the ethyl peroxide lactate, and afterwards focused as well as distilled under minimized pressure. Get Ethyl 2-Oxopropanoate. Acrylate oxidation: Acrylate is oxidized with H2O2 in the presence of Cr or V compound catalyst to generate pyruvate. As an example, isopropyl acrylate is mixed in the acetonitrile solvent in the presence of chromium triacetyl acetate as well as H2O2 is added. The response temperature level is 50 ° C and also acetone is obtained in 8 hours. Acid isopropyl ester, selectivity is 99.1%, conversion price is 87.9%. An additional instance is that methyl acrylate is reacted with triethylamine in the presence of chromium triacetoacetate or chromic acid for 20 hours at a temperature of 40 ° C, a selectivity of 72%, as well as a conversion price of 82% to obtain methyl pyruvate. Furthermore, pyruvic aldehyde and methanol respond in the gas phase in the presence of a nickel phosphate stimulant to acquire methyl pyruvate.

Protective Effect of Ethyl Pyruvate on Hepatocytes in Septic Mice

Research the safety result of ethyl pyruvate (EP) on liver cells in septic computer mice. Approaches: A computer mouse cecal ligation and puncture version was produced. Ringer’s ethyl pyruvate solution (REPRESENTATIVES) as well as Ringer’s lactate solution (RLS) were used to execute liquid resuscitation on the computer mice, as well as the antioxidant capacity and liver function changes of liver tissue were found. Results: The antioxidant capability of septic mice was lower than that of the sham operation team, P<0.01. The application of REPS resuscitation considerably boosted the antioxidant ability of liver tissue. The concentration of malondialdehyde in liver cells in the REPS team was less than that in the RLS team [( 48.18 ± 5.98) μmol · g ^ -1 protein vs (78.34 ± 11.16) μmol · g ^ -1 healthy protein], superoxide dismutase [( 5.19 ± 1.41) 10 ^ 3 U/g healthy protein vs (3.20 ± 1.08) 10 ^ 3 U/g healthy protein] and The total antioxidant ability [( 7.02 ± 1.79)10 ^ 3 U/g healthy protein vs (4.77 ± 1.35) 10 ^ 3 U/g protein] was more than that of the RLS team, P<0.01; The alanine aminotransferase of mice in the representatives group was less than that in the RLS team, [( 210.06 ± 23.36) U vs (458.86 ± 51.55) U], P<0.01. Verdict: Ethyl pyruvate has considerable antioxidant effects, enhances the antioxidant capacity of liver cells in septic computer mice, as well as improves liver function.

About Products:
If you need the cosmetic raw material Ethyl 2-Oxopropanoate, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Ethyl 2-Oxopropanoate manufacturer and supplier, ZSpharmac will provide Ethyl 2-Oxopropanoate raw materials to customers around the world for a long time.
Over the years, the company has adhered to the spirit of “integrity management, strict quality control, and customer first” and has won unanimous praise from customers at home and abroad.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.