Zhishang Chemical

Welcome to Zhishang Chemical      +86-176 5311 3209     Simon@sdzschem.com

Zhishang Chemical
Close this search box.

Erythrosin B CAS 16423-68-0

Molecular Formula: C20H9I4NaO5

Formula Weight: 859.89

ZSpharmac: Erythrosin B Supplier

Product Name: Erythrosin B
CAS No: 16423-68-0
Purity: 99%

Navigation Bar

Basic Info

Product Name:Erythrosin B
Other Names:Food Red No. 3
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:Deep Red to Brown Fine Powder
EINECS No.:240-474-8
Storage:Room Temp
Provide:Erythrosin B MSDS;
Erythrosin B COA

What is Erythrosin B?

Erythrosine B, additionally referred to as tetraiodofluorescein B, is a red or reddish-brown granule or powder, odorless, soluble in water, soluble in ethanol, propylene glycol as well as glycerin, insoluble in oil. It has excellent dyeing residential properties, particularly for protein dyeing. Compared to various other artificial red pigments of the same kind, it has far better heat resistance, alkali resistance, redox resistance and also coloring power, so it can be extensively used in fermented food, baked food, gelato, fish cake, pickled Products and various other non-acidic foods.

Erythrosin B Property

Melting point 142~144℃
density 0.98
vapor pressure 0Pa at 25℃
Fp 285℃
storage temp. room temp
solubility 100g/l
Colour Index 45430
pka4.1(at 25℃)
form Fine Powder
color Deep red to brown
PH6-7 (10g/l, H2O, 20℃)
PH Range0(yellow)-3.6(red)
Water Solubility Soluble in water


Erythrosin B Uses

  1. Erythrosine B is made use of for tinting food, medicine and also cosmetics.
  2. Erythrosine B is mostly made use of as a plastic lubricating substance, appropriate for polyethylene, polypropylene, polystyrene, abdominal material, polyvinyl chloride and various other thermoplastic and also thermosetting plastics.
  3. Erythrosine B is used as a food tinting agent. It can be used in red and also green silk and also dyed tinned cherries (for design) according to the guidelines of our country. The optimum usage is 0.10 g/kg; In bread designs and also eco-friendly plums, the optimum dosage is 0.05 g/kg.
  4. Erythrosine B is utilized as edible red pigment. Extensively used in fermented food, baked food, gelato, fish cake, pickled products as well as other non-acidic food, and also can additionally be made use of along with other food coloring. Except drinks and hard candies. The dosage is 5-100mg/ kg.
  5. Erythrosine B was utilized as an adsorption indicator for precipitation titration. Fluorescent indicator for acid-base titration, no fluorescence when pH is greater than 2.5, light eco-friendly fluorescence when pH is not less than 4.0. Photometric reagents. Organic spots.

Application of Erythrosine B

Application one,
CN201711490307.4 reports a method for measuring chitosan content by fading spectrophotometry using erythrosine B as a probe, which belongs to the field of macromolecular detection. The present invention utilizes chitosan to react with erythrosine B under weakly acidic conditions to form an associate, and its absorbance is significantly lower than that of erythrosine B measured at 530 nm by a spectrophotometer, and the reduction value of absorbance is the same as that of chitosan The concentration of sugar is directly proportional, and as the quantitative basis of chitosan, a fading spectrophotometric method for the determination of chitosan has been established. The determination of this method is affected by the molecular weight of chitosan, and it has cheap reagents and high sensitivity and reproducibility. Good advantages, suitable for promotion and use in practical applications.

Application two,
CN201110341025.4 protects a solid medium pollen, its preparation method and the application of the solid medium pollen in the ecological safety evaluation of transgenic crops such as transgenic cotton. The solid medium pollen is a red powdery pollen obtained by soaking collected pollen in erythrosin B solution, dyeing it, drying it and sieving it. The distance and direction of pollen diffusion of transgenic crops such as transgenic cotton can be detected by using the solid medium pollen, so that the ecological safety of transgenic crops such as transgenic cotton can be studied.

The Production Method of Erythrosine B

Prep Work of Erythrosine B.
Warmth resorcinol to melt, include phthalic anhydride and also mix to thaw, warmth to 185 ° C and react for half a hr to generate dark yellow resorcinolphthalein, which remains in fluid state right now. Include powdered anhydrous zinc chloride under mixing, stir till totally liquified, and also gradually raise the temperature to 210-215 ° C, warmth till the reactant is entirely strengthened, after that trendy as well as shatter to obtain a crude melt; mix the unrefined thaw with dilute hydrochloric acid Home heating as well as azeotroping, leaching zinc chloride and also residual resorcinol, filtering system, cleaning with water, as well as drying, after that drawing out unreacted resorcinolphthalein with ethanol, and also drying out the drawn out product to get fluorescein.
Dissolve fluorescein in sodium hydroxide remedy, include iodine to respond, add hydrochloric acid to the reactant, speed up crystals, then transform it right into sodium salt remedy, and also concentrate to obtain the product. Preparation of erythrosin aluminum lake.
Aluminum hydroxide is prepared from light weight aluminum salts such as aluminum chloride as well as light weight aluminum sulfate and also antacid such as sodium carbonate, and afterwards contributed to Erythrosine B liquid service to precipitate to acquire the item.

Study on Meclofenoxate Hydrochloride and Erythrosin B

Accurately draw an appropriate amount of solution containing meclofenoxate hydrochloride and place it in a 10 mL colorimetric tube, add 3.00 mL0.5 mmol/L erythrosine B solution and 2.0 mL pH2.6 Clark-Lubs buffer solution accurately in turn, add distilled water Make up to volume and shake well. Prepare reagent blank solution at the same time, and measure the absorbance A of the solution at 554 nm with the reagent blank solution as a reference.

The maximum absorption wavelength of erythrosine B is 520nm, and the maximum absorption wavelength of the ionic association formed between erythrosine B and meclofenoxate hydrochloride is at 554 nm. Select 554m as the measurement wavelength.

The influence of pH value on the system was investigated, and it was found that when the pH was between 2.2 and 3.0, the absorbance at 554nm was the largest and stable, and when the pH was greater than 3.0 or less than 2.2, the absorbance decreased. Therefore, the pH26 Clark-Lubs buffer solution was selected in the subsequent tests, and it was determined through experiments that the most suitable solution was 2.0 mL. For 50ug meclofenoxate hydrochloride, the absorbance of the erythrosine B solution in the range of 2.50-4.00mL is the largest: the amount is too small to react completely, and the amount is too large to be unfavorable for the reaction and the absorbance is weakened. Therefore, 3.0 mL of 0.5 mmol/L erythrosin B solution was used. The absorbance of the system is stable at room temperature of 20-30°C.

For 50ug meclofenoxate hydrochloride under the experimental conditions, the allowable addition amount (in mg, relative deviation less than 5%) of co-existing components is respectively glucose (4), D fruit field, maltose (5), sucrose (7), Lactose (10), Starch (20). This shows that these components that may exist in the meclofenoxate preparation have no influence on the determination of meclofenoxate. Take 10 bottles of Su Rui Suo (Meclofenoxate Hydrochloride for Injection) in the market or take 10 capsules of Jiannaosu (Meclofenoxate Hydrochloride) in the market, and drain the contents. Mix well, and after accurate weighing, accurately weigh one-tenth of the total mass, add a small amount of water to dissolve, and dilute to 1 L (concentration: 100 mg/L) with water to obtain a sample treatment solution. The test results were consistent with those obtained by the Chinese Pharmacopoeia method.

About Products:
If you need Erythrosin B, the cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Erythrosin B manufacturer and supplier, ZSpharmac will provide Erythrosin B raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Erythrosin B Quotation