Oligopeptide-1 ≠ Human Oligopeptide-1
On January 10, 2019, the State Drug Administration clearly mentioned that oligopeptide-1 as well as Epidermal Growth Element (Skin Growth Aspect, EGF) are not the same material.
Oligopeptide-1 is included in my country’s “Brochure of Names of Aesthetic Raw Materials Made Use Of” (2015 edition), and also is typically made use of as a skin conditioning representative. Nonetheless, human oligopeptide-1 is not included in this brochure, and also is generally used much more in the clinical area. Currently, EGF is primarily used as a medical outside preparation for the therapy of skin burns and also scald injuries (superficial II level to deep II level burns and also scald wounds), residual wounds, contributor website injuries and also persistent ulcer injuries, or for the treatment of microneedle, laser wait on postoperative fixing. These wounded skins are utilized under the guidance of a physician’s diagnosis and there is no problem.
It is not recommended for normal skin, since the skin is hard to take in. We understand that molecules smaller sized than 500-800 Daltons can be easily taken in by the skin. The molecular weight of this EGF is 6200, so the skin can not absorb it.
Due to its huge molecular weight, Epidermal Development Variable is hard to be absorbed under typical skin obstacle conditions. When the skin obstacle feature wants, various other potential safety issues might arise. Due to efficiency and also safety and security factors to consider, Epidermal Development Element should not be utilized as a cosmetic basic material.
Consequently, unlike oligopeptide-1, Epidermal Growth Variable can not be made use of as a cosmetic basic material. It is prohibited to include human oligopeptide-1 or Epidermal Growth Factor to the formula or claim to consist of human oligopeptide-1 or Skin Development Element.