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Eleutheroside CAS 7374-79-0

Molecular Formula: C28H36O13

Formula Weight: 580.58

ZSpharmac: Eleutheroside Supplier

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Product Name: Eleutheroside
CAS No: 7374-79-0
Purity: 99%

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Basic Info

Product Name:Eleutheroside
Other Names:ELEUTHEROSIDE E1
CAS:7374-79-0
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Powder
EINECS No.:N/A
Storage:2-8°C
Provide:Eleutheroside MSDS;
Eleutheroside COA

What is Eleutheroside?

Eleutheroside is a remove from the root as well as root bark of Araliaceae plants. It draws out and separates a selection of compounds from the origins as well as stems of Acanthopanax, and also its chemical structure is complex. The primary energetic components are eleutherosides A, B, B1, C, D, E, F, G and eleutheroside polysaccharides. Additionally, it additionally consists of sugar, sucrose, carotene, vitamins as well as other ingredients.

Eleutheroside Property

Melting point 182-183 °C
Boiling point 778.5±60.0 °C(Predicted)
density 1.399±0.06 g/cm3(Predicted)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder

 

Pharmacological Effects of Eleutheroside

1. Anticancer result
Eleutheroside has a certain inhibitory effect on pet experimental hair transplanted lumps, drug-induced lumps, cancer cells transition and spontaneous leukemia in computer mice.
2. The result on the cardiovascular system
Eleutheroside can improve the blood supply to the mind, inhibit platelet gathering, as well as is also antiarrhythmic.
3. Gonadotropic impact
Eleutheroside advertises precocious the age of puberty and weight gain in male as well as female mice.
4. Anti-fatigue result
Eleutheroside and its essences have obvious anti-fatigue effects, as well as are more powerful than ginseng.
5. “Adjust as is” function
Eleutherosides can alter the pathological process of the body’s tension action sharp period, avoid adrenal hyperplasia throughout this procedure, minimize cholesterol degrees, diminish thymus and also reduce gastric bleeding. Acanthopanax extract has the same “adaptogenous” results as ginseng.
6. Anti-bacterial impact
The alcohol essence of Acanthopanax can raise the phagocytosis percent and phagocytosis index of macrophages phagocytizing red cell. The alcohol essence as well as water essence of Acanthopanax senticosus have inhibitory result on Yeast infection albicans, and the alcohol essence likewise has certain anti-bacterial impact on Escherichia coli.
7. Raise the body’s resistance to dangerous factors
Eleutheroside can reduce the level of sensitivity of regular skin to ultraviolet radiation and boost the resistance of capillaries in hypoxic problems.
8. Effects on the genitourinary system
Eleutheroside and total glycosides isolated from leaves or Acanthopanax B or E can raise body weight, prostate as well as seminal blister weight and also registered nurse web content. It can additionally raise the egg manufacturing of chickens, and also raise the overall nitrogen and also protein in the oviduct.
9. Impacts on the respiratory system
Oral eleuthero alcoholic mixture service has substantial antitussive impact Acanthopanax origin is taken by mouth, and it has evident expectorant impact.
10. Sedative result.
The intraperitoneal shot of 10g/kg alcoholic remove liquid remedy can substantially prevent the boost of spontaneous activity in computer mice caused by sodium benzoate caffeine, and also can substantially extend the bedtime of mice brought on by amobarbital salt, and also shorten the latency period for sleeping. Intraperitoneal shot of water-soluble polysaccharide remove of alcoholic remove, 0.5 mL of 50% remedy per intraperitoneal shot, although it might not lengthen the death time of mice injected with picrotoxin, it might significantly lengthen the latency period of convulsions in computer mice.
11. Results on immune feature
Offering test subject acanthopanax ethanol essence remedy once daily can considerably improve the phagocytosis of chicken erythrocytes by test subject peritoneal inflammatory exudate cells induced by peptone soup medium; enhance the phagocytosis of charcoal bits by the reticuloendothelial system of mice. Acanthopanax has a significant precautionary result on the leukopenia brought on by benzene in mice as well as rabbits; it also has a safety impact on the leukopenia caused by shot of cyclophosphamide. Acanthopanax polysaccharide intraperitoneal shot can substantially improve the PFC of computer mouse spleen producing IgM; enhance the PFC of computer mouse spleen secreting IgG and the postponed type hypersensitivity (DTH) of computer mice caused by BSA. Acanthopanax can significantly enhance the work of CTL to eliminate target cells, as well as likewise has a strong mitogenic influence on computer mouse entire spleen cells and spleen cells after T cell elimination, as well as in addition can market ConA-stimulated computer system mouse spleen cells to secrete interleukins -2 (IL-2). Acanthopanax polysaccharide can in a similar way substantially boost the growth response of computer system mouse splenocytes to ConA and additionally LPS; it can considerably increase the information antibody secretion index of computer mice.

Determination Method of Eleutheroside

Decision of the content of eleutheroside by ultraviolet spectrophotometry:
Accurately consider 5 mg of the syringin referral compound and also dissolve it in 100 ml of methanol. Take 1.0, 2.0, 3.0, 4.0 and also 5.0 ml of the above option respectively to a 10ml volumetric flask, and include methanol to the equivalent volume. Methanol was made use of as an empty control. Absorbance was gauged at a wavelength of 266 nm. Draw a typical contour with absorbance as the ordinate and also concentration as the abscissa.
Accurately weigh Eleutheroside, put it in a Soxhlet extractor, add absolute ethanol to reflux for 16 hrs, gather the solvent into a small container, add silica gel and also stir extensively, evaporate to dryness on a water bathroom; transfer to a column, and after that wash with 100ml chloroform Elute, throw out the eluent; after that elute with chloroform-methanol (9:1), gather 3000ml eluent, recuperate the solvent, dissolve the residue with 1.0 ml methanol, take 50u factors on the silica gel G-CMC thin-layer chromatography plate, usage Establish with chloroform-methanol (8:2), cut out the dark blue fluorescent part under the ultraviolet light into a test tube, eliminated the blank part on the plate as a control, include 5.0 ml methanol exactly, liquify, mix and also centrifuge, and pipette the supernatant service and measure the absorbance at a wavelength of 266 nm. The logical results of syringin were calculated by the conventional curve.

Method for the Manufacture of Eleutheroside

The medicinal product is grated right into a crude powder with a pulverizer, put into a multifunctional standard Chinese medicine removal storage tank, add deionized water, mix and boil for extraction, and launch the fluid; put the extraction liquid right into a three-legged centrifuge, centrifuge to eliminate slag, and obtain a centrate. Concentrate under decreased stress to obtain an extract of 10-18 Baume (thermal test), spray-dry to obtain completely dry powder, pulverize the dry powder, go through a 60-80 mesh sieve, mix and pack to obtain a completed item. This procedure is suitable for the manufacturing of Acanthopanax senticosus essence containing about 1.2% eleutheroside, as well as the yield is 4% to 5%.
Removal and splitting up of overall polysaccharides: the quantity of water utilized is 12 times the quantity of medicinal materials; the preparation time is 6 hrs; the concentration of the water preparation before alcohol precipitation is 1.5.

刺五加多糖提取工艺

About Products:
If you need Eleutheroside, the cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced Eleutheroside manufacturer and supplier, ZSpharmac will provide Eleutheroside raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

 

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

 

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get Eleutheroside Quotation