EDTA Disodium Salt CAS 6381-92-6

Molecular Formula: C10H19N2NaO9

Formula Weight: 334.26

ZSpharmac: EDTA Disodium Salt Supplier

Product Name: EDTA Disodium Salt

CAS No: 6381-92-6

Purity: 99%

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Basic Info

Product Name:	EDTA Disodium Salt
Other Names:	Disodium Edetate Dihydrate
CAS:	6381-92-6
Place of Origin:	Shandong, China
Brand Name:	ZSpharmac
Type:	Cosmetic Raw Materials
Appearance:	White Crystal
EINECS No.:	613-386-6
Storage:	Room Temp
Provide:	EDTA Disodium Salt MSDS； EDTA Disodium Salt COA

What is EDTA Disodium Salt?

EDTA Disodium Salt, additionally called disodium ethylenediaminetetraacetic acid, is a great complexing representative in chemistry. It has six coordination atoms, and also the complicated created is called a chelate. EDTA is typically used in control titration. Normally, the content of metal ions is figured out. EDTA Disodium Salt is a food additive allowed by GB2760. It can prevent or delay food from fading, oxidation, rancidity, turbidity and flavor change, and it can protect food from color, stability, anti-oxidation and antisepsis. EDTA Disodium Salt can form a stable water-soluble complex with iron, copper, calcium, magnesium and other multivalent ions, and use its complexation to prevent discoloration, deterioration, turbidity and oxidative loss of vitamin C caused by metals. Play color protection, anti-oxidation effect. Disodium EDTA is widely used in soft drinks (0.03 g/kg); jam, vegetable puree (sauce), etc. (0.07 g/kg); compound seasoning, mayonnaise, salad dressing, etc. (0.075 g/kg); pickled vegetables , pickles, canned vegetables, canned nuts and seeds, canned eight-treasure porridge, preserved sweet potatoes, etc. (0.25/kg).

EDTA Disodium Salt Property

Melting point	250 °C (dec.)(lit.)
Boiling point	>100 °C
density	1.01 g/mL at 25 °C
refractive index	n20/D 1.363
Fp	>100℃
storage temp.	room temp
solubility	3 M NaOH: 100 mg/mL
pka	pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C)
form	crystalline
color	≤5 (0.5 M)(APHA)
Odor	Odorless
PH Range	4 – 5 at 10 g/l at 23 °C
PH	4.0-5.5 (25℃, 0.1M in H2O)
Water Solubility	soluble

Application of EDTA Disodium Salt

1. EDTA Disodium Salt can be used as a complexing agent (coordinating agent) to remove heavy metal ions (including Ca2+, etc.);

2. It can also be used as a masking agent;

3. EDTA Disodium Salt is also used as a buffer in some medicines.

4. In actual application, use its complexation to prevent discoloration, deterioration, turbidity and oxidative loss of vitamin C caused by metals. This product has a synergistic effect with phosphate.

5. EDTA Disodium Salt is used as a water treatment agent, which can prevent the adverse effects of calcium, magnesium, iron, manganese and other metal ions in the water.

6. Trace metals (iron, copper, etc.) in oil can promote the oxidation of oil. This product can complex with trace metal ions, which can improve the anti-oxidation of oil and prevent food from discoloring.

7. Disodium EDTA is mainly used as a chelating agent, which plays a stabilizing role in cosmetics, and a mineral chelating agent, which can synergize with anti-corrosion. And it has a certain synergistic effect on the anti-corrosion system and anti-oxidation system.

8. EDTA Disodium Salt is utilized as whitening and taking care of service and also dyeing auxiliaries in the handling of color photosensitive materials, fiber therapy agent, aesthetic additive, medicine, food, agricultural chemical fertilizer production, blood anticoagulant, water softener in cleaning agent, Stabilizer, synthetic rubber, polymerization initiator and heavy metal quantitative analysis representative, and so on.

Preparation and Calibration of EDTA Disodium Salt Standard Solution

1. Reagents Disodium ethylenediaminetetraacetic acid (EDTA), zinc oxide (baseline reagent), hydrochloric acid solution, 10% ammonia water, ammonia-ammonium chloride buffer solution, 0.5% chrome black T indicator (ethanol solution).

2. Preparation and calibration of 0.05M and 0.02M EDTA standard solutions: (1) Preparation of EDTA Disodium Salt: 1) 0.05M EDTA solution: Dissolve 20g of EDTA disodium in 1 L of distilled water and shake well. 2) 0.02M standard solution: Dissolve 8 g of disodium edetate in 1 L of high-purity water and shake well. (2) Calibration of EDTA Disodium Salt: 1) Calibration of 0.05MEDTA standard solution: Weigh 1g of reference zinc oxide (accurate to 0.2mg) burned at 800°C to constant weight, moisten with a little distilled water, add hydrochloric acid solution ( 1+1) until the sample is dissolved, transfer to a 250ml volumetric flask, dilute to the mark, and shake well. Take 20.00ml of the above solution, add 80ml of water, neutralize with 10% ammonia water until the pH is 7~8, add 5ml of ammonia-ammonium chloride buffer solution (PH=10), add 5 drops of 0.5% chrome black T indicator, and use 0.05M EDTA solution was titrated until the solution changed from purple to pure blue. 2) Calibration of 0.02M EDTA Disodium Salt: Weigh 0.4g (accurate to 0.2mg) of reference zinc oxide burned at 800°C to constant weight, moisten with a little distilled water, add hydrochloric acid solution (1+1) until the sample is dissolved, and transfer to 250ml In a volumetric flask, dilute to the mark and shake well. Take 20.00ml of the above solution, add 80ml of water, neutralize with 10% ammonia water until the pH is 7~8, add 5ml of ammonia-ammonium chloride buffer solution (PH=10), add 5 drops of 0.5% chrome black T indicator, and use 0.02M EDTA Disodium Salt was titrated until the solution changed from purple to pure blue. The molar concentration (M) of EDTA standard solution is calculated according to the following formula:

In the formula, G——the weight of zinc oxide, g; V——the volume of EDTA solution consumed during titration, ml; 0.08——take 20ml of 250ml for titration, which is equivalent to 0.08 times of G; 0.08138——per millimole of zinc oxide ( ZnO) weight.

Production Method of EDTA Disodium Salt

Sodium cyanide method
Slowly add the mixture of sodium cyanide and formaldehyde into the aqueous solution of ethylenediamine according to a certain ratio, and let air flow in under reduced pressure at 85°C to remove ammonia. After the reaction is completed, adjust the pH value to 4.5 with concentrated sulfuric acid, and then decolorize, filter, concentrate, crystallize and dry to obtain the finished product.
Chloroacetic acid method
First mix 100kg of chloroacetic acid, 100kg of ice and 135kg of 30% NaOH solution, add 18kg of 83% to 84% ethylenediamine under stirring, and keep warm at 15°C for 1h. Slowly add 30% NaOH solution in batches until the reactant is alkaline, and keep it at room temperature for 12h. Heat to 90°C, add activated carbon for decolorization. The filtrate was adjusted to pH 4.5 with hydrochloric acid, concentrated at 90°C, and filtered; the filtrate was cooled, crystallized, separated, washed, and dried at 70°C to obtain EDTA Disodium Salt.

About Products:
If you need EDTA Disodium Salt as a cosmetic raw material, please contact our service staff directly, we will provide you with high-quality products at the best price.
As an experienced EDTA Disodium Salt manufacturer and supplier, ZSpharmac will provide EDTA Disodium Salt raw materials to customers all over the world for a long time.
Over the years, the company has been adhering to the spirit of “integrity management, strict quality control, customer first”, and has won unanimous praise from domestic and foreign customers.

Company Profile and Corporate Culture

Company Profile：

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture：

OUR MISSION
Help China Chemicals to benefit the happiness of human life
OUR VISSION
Become the most trusted chemical supplier in the world
OUR BUSINESS PHILOSOPHY
Striver – oriented, enrich employees, customer first, deep service, seek development
OUR VALUES
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info

Business Type: Manufacturer
Product Range: Cosmetic raw materials
Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
Total Employees: 51~100
Capital (Million US $): 10000000RMB
Year Established: 2016

Production Capacity

No. of Production Lines : 8
No. of QC Staff : 5 -10 People
OEM Services Provided : yes
Factory Size (Sq.meters) : 3,000-5,000 square meters
Certificate: ISO9001 , CE , GMP , API , MSDS
Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.

Service

Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.

FAQ

Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.

HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?

You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

Is there a discount?

Different quantity has different discount.

Shipping

1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.