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DL-Serine CAS 302-84-1

Molecular Formula: C3H7NO3

Formula Weight: 105.09

ZSpharmac: DL-Serine Supplier

Product Name: DL-Serine
CAS No: 302-84-1
Purity: 99%

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Basic Info

Product Name:DL-Serine
Place of Origin:Shandong, China
Brand Name:ZSpharmac
Type:Cosmetic Raw Materials
Appearance:White Crystalline Powder
EINECS No.:206-130-6
Storage:Store Below +30°C.
Provide:DL-Serine MSDS;
DL-Serine COA

What is DL-Serine?

DL-Serine is an amino acid that is a racemic mixture of D-serine and L-serine. Serine is a non-essential amino acid, meaning it is synthesized naturally in the body and does not need to be taken directly from food. DL-Serine is chemically classified as an aliphatic amino acid, and its molecular structure contains an α-amino (NH2) and an α-carboxylic acid (COOH) groups, as well as a unique β-hydroxyl (-OH) side chain . Its molecular formula is C3H7NO3 and its molecular weight is 105.09.

DL-Serine Property

Melting point 240 °C (dec.) (lit.)
Boiling point 197.09°C (rough estimate)
density 1.53
refractive index 1.4368 (estimate)
storage temp. Store below +30°C.
solubility H2O: soluble
form Crystalline Powder
pka2.19(at 25℃)
color White
Water Solubility 50.23 g/L (25 ºC)


DL-Serine Uses

1. Medicine and Biopharmaceuticals
Neuroscience research: The L-isomer of DL-Serine (L-Serine) is an important neurotransmitter and regulator of excitatory neurotransmission in the brain, participating in glutamate receptor-mediated signal transduction. Therefore, DL-Serine is often used as a research material for neuroprotective agents, especially when studying treatment options related to brain diseases such as Alzheimer’s disease, multiple sclerosis and schizophrenia.

Cell Culture: In cell culture media, DL-Serine acts as an amino acid supplement to support cell growth and protein synthesis, especially for specific cell lines that require precise nutritional balance.

2. Cosmetics and personal care products
Skin Care: DL-Serine is used in some skin care products due to its moisturizing and skin-friendly properties to help improve skin hydration and promote skin health.

3. Agriculture and plant protection
Antiviral agent: DL-Serine has shown inhibitory effects on certain plant viruses such as tobacco mosaic virus (TMV), suggesting that it may be developed as an environmentally friendly plant protection agent for viral disease control in crops.

4. Food and feed additives
Nutritional supplements: Although DL-Serine is not as commonly found in food supplements as L-Serine, under certain conditions it can be used as a nutritional supplement, especially in specific feed formulations that require a balanced amino acid profile.

5. Chemistry and Materials Science
Organic synthesis intermediates: DL-Serine is used as a starting material or intermediate in organic synthesis and can be used to prepare complex organic molecules, such as drug molecules, bioactive peptides and polymer precursors.

6. Research and education
Biochemical reagents: In biochemistry and molecular biology research, DL-Serine can be used as an experimental reagent to study protein structure, enzyme activity determination, and biosynthetic pathway exploration.

Prominent Applications of DL-Serine in Cosmetics

1. Moisturizing effect
DL-Serine, as an amino acid, attracts and retains moisture, promoting skin hydration. It interacts with the skin’s natural moisturizing factor (NMF) to help maintain the skin’s moisture balance and reduce water loss, thereby keeping the skin soft and smooth. This moisturizing property makes DL-Serine a beneficial ingredient in moisturizing products such as moisturizers, lotions, serums and masks.

2. Skin barrier repair and protection
Amino acids are the building blocks of skin proteins, such as collagen and elastin, and are essential for maintaining skin structure and function. As one of the sources of amino acids, DL-Serine can assist in the repair and strengthening of the skin barrier, helping to protect the skin from damage from the external environment (such as pollutants and climate change). It is especially suitable for the care of dry, damaged or sensitive skin. in the product.

3. Mildness and low irritation
Since DL-Serine is one of the naturally occurring amino acids in the human body, it is generally considered gentler and less irritating to the skin. Therefore, it is suitable for developing cosmetic formulas specifically for sensitive skin, reducing the possibility of irritation and discomfort, improving product application range and user satisfaction.

4. Supplementary nutrition supply
In cosmetic formulations, DL-Serine can be used as an ingredient in skin nutritional supplements to help provide amino acids that support the normal metabolism and repair process of skin cells and promote healthy skin appearance.

5. Formula Compatibility
Due to its chemical properties, DL-Serine is easy to compound with other cosmetic raw materials and can be stably integrated into a variety of cosmetic systems without easily affecting the texture or stability of the product, increasing its flexibility in cosmetic formula design.


National Center for Biotechnology Information. PubChem Compound Summary for CID 617, DL-Serine. https://pubchem.ncbi.nlm.nih.gov/compound/DL-Serine. Accessed May 17, 2024.

As a company specializing in the production and supply of DL-Serine raw materials, we are committed to providing customers with high-quality products and preferential prices. We have rich experience and technology to ensure product quality and stable supply. No matter where you are, we can provide you with the DL-Serine raw materials you need to support your production and research and development.

We always adhere to the principle of honest operation, strictly control product quality, and serve every customer with a customer-first attitude. Over the years, we have established good cooperative relationships with customers at home and abroad and won their trust and praise.

If you have needs or are interested in our products, please contact our service staff directly, we will wholeheartedly provide you with the best quality services and products. Looking forward to cooperating with you and developing together!

Company Profile and Corporate Culture

Company Profile:

ZhiShang Chemical is owned by ZhiShang Group is a professional new-type chemicals enterprise combined into research and development, production and sales .

The company’s competitive product is pharmaceutical raw materials and intermediates (especially carbohydrate derivatives Series), In recent years, the company has made a major breakthrough in food and feed additives, plant extraction, industrial chemicals industry .

The company insists on the spirit of “sincere management, strict quality control, customer as god” , get consistent high praise from customers at home and abroad.

Corporate Culture:

Help China Chemicals to benefit the happiness of human life
Become the most trusted chemical supplier in the world
Striver – oriented, enrich employees, customer first, deep service, seek development
Be prepared for danger in times of peace, forge ahead actively, unity and cooperation, and be brave to fight

About Us

The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.

“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Company Info
  • Business Type: Manufacturer
  • Product Range: Cosmetic raw materials
  • Products/Service:Cosmetic raw materials (flavors and fragrances,antioxidant products, moisturizing and hydrating, whitening agents, cosmetic additives)
  • Total Employees: 51~100
  • Capital (Million US $): 10000000RMB
  • Year Established: 2016
Production Capacity
  • No. of Production Lines : 8
  • No. of QC Staff : 5 -10 People
  • OEM Services Provided : yes
  • Factory Size (Sq.meters) : 3,000-5,000 square meters
  • Certificate: ISO9001 , CE , GMP , API , MSDS
  • Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.


Pre-Sales Service

* Prompt reply and 24 hours online, professional team to provide best price and high quality product.

* Sample testing support.

* Every batch of products will be tested to ensureits quality.

*The packing also can be according the customers` requirment.

*Any inquiries will be replied within 24 hours.

*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.


After-Sales Service

*The fact of logistics information monitoring.

* Any questions about the product can be consulted at any time.

*Product has any problem can return.


Do you accept sample order?

We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.



You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

What’s your MOQ?

Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Do you supply product report?

Yes. We’ll give you product analysis report before shipping.

  Is there a discount?

Different quantity has different discount.


1. ≤50kg, Express delivery recommended, usually called as DDU service;

2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;

3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;

4. For high value products, please select air shipping and express delivery for safe.

Get DL-Serine Quotation